Zylet Drops

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|Zylet Drops

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Zylet Drops


Generic Name: Loteprednol/Tobramycin Eye Drops (loe-te-PRED-nol/toe-bra-MYE-sin)
Brand Name: Zylet

Zylet Drops is used for:

Treating certain types of eye inflammation in which an infection or risk of infection is present.

Zylet Drops is a combination of a corticosteroid and antibiotic. It reduces inflammation and treats or protects against infection due to certain bacteria.

Do NOT use Zylet Drops if:

  • you are allergic to any ingredient in Zylet Drops or to similar medicines, including corticosteroids or aminoglycoside antibiotics.
  • you have a viral disease in the eye, including herpes simplex keratitis (dendritic keratitis), vaccinia, or varicella
  • you have a mycobacterial or fungal infection of the eye

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zylet Drops:

Some medical conditions may interact with Zylet Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have glaucoma, thinning of certain parts of the eye (the cornea or the sclera), or a history of herpes simplex infection, or have recently had cataract surgery
  • if you have diabetes or wear contact lenses

Some MEDICINES MAY INTERACT with Zylet Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Certain diuretic medicines (eg, furosemide), cyclosporine, nonsteroidal anti-inflammatory medicines (NSAIDs), or other medicines containing aminoglycoside antibiotics (eg, tobramycin, gentamicin) because the risk of their side effects may be increased by Zylet Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Zylet Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zylet Drops:

Use Zylet Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Zylet Drops is to be used as eye drops. It is not to be injected into the eye.
  • Shake well before each use.
  • To use Zylet Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
  • To clear up your infection completely, take/use Zylet Drops for the full course of treatment. Keep taking/using it even if you feel better in a few days.
  • Zylet Drops is usually used for a maximum of 2 weeks. If it is used for longer than 10 days, eye exams may be required.
  • If you miss a dose of Zylet Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Zylet Drops.

Important safety information:

  • Zylet Drops may cause blurred vision. Use Zylet Drops with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly.
  • If your symptoms do not get better after 2 days or if they get worse, contact your health care provider.
  • Soft contact lenses may absorb a chemical in Zylet Drops. Do not wear contact lenses while you are using Zylet Drops.
  • Tell your doctor or dentist that you take Zylet Drops before you receive any medical or dental care, emergency care, or surgery.
  • Zylet Drops only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Be sure to use Zylet Drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Zylet Drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Lab tests, including eye examinations, may be performed while you use Zylet Drops. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Zylet Drops should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zylet Drops while you are pregnant. It is not known if Zylet Drops is found in breast milk. If you are or will be breast-feeding while you use Zylet Drops, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Zylet Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning or stinging upon using Zylet Drops; mild itching, discomfort, or redness of the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; sensitivity to light; severe or worsening pain, redness, swelling, or discharge from the eye or eyelid; unusual tearing.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Zylet Drops:

Store upright, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Do not freeze. Keep Zylet Drops out of the reach of children and away from pets.

General information:

  • If you have any questions about Zylet Drops, please talk with your doctor, pharmacist, or other health care provider.
  • Zylet Drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about this medicine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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