ZORprin Controlled-Release Tablets

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ZORprin Controlled-Release Tablets


Generic Name: Aspirin Controlled-Release Tablets 800 mg and Delayed-Release Tablets (AS-pir-in)
Brand Name: Examples include Bayer Low Adult Strength and ZORprin

ZORprin Controlled-Release Tablets is used for:

Treating pain including, headache, muscle aches, sprains, tooth extraction and toothache, menstrual cramps, arthritis and rheumatism, and pain and fever of the common cold. However, since ZORprin Controlled-Release Tablets is enteric coated and has delayed absorption compared with other brands of ZORprin Controlled-Release Tablets, it will not provide fast relief of headaches, fever, or other symptoms needing immediate relief. It may be used to reduce the risk of death and lessen the damaging effects of an acute heart attack. ZORprin Controlled-Release Tablets is also used to reduce the risk of heart attacks and strokes in certain men and women who have already had a heart attack or ischemic stroke. It may also be used to treat certain conditions as determined by your doctor which may not be listed in the professional package insert.

ZORprin Controlled-Release Tablets is a nonsteroidal anti-inflammatory drug (NSAID). It works by inhibiting several different chemical processes within the body that cause pain, inflammation, and fever. It also reduces the tendency for blood to clot.

Do NOT use ZORprin Controlled-Release Tablets if:

  • you are allergic to any ingredient in ZORprin Controlled-Release Tablets
  • you are a child or teenager with influenza (flu) or chicken pox
  • you have bleeding problems such as hemophilia, von Willebrand disease, or low blood platelets
  • you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness), to aspirin, tartrazine, or an NSAID (eg, ibuprofen, naproxen, celecoxib)
  • you are taking anticoagulants (eg, heparin, warfarin) or methotrexate

Contact your doctor or health care provider right away if any of these apply to you.

Before using ZORprin Controlled-Release Tablets:

Some medical conditions may interact with ZORprin Controlled-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines or other substances
  • if you have alcoholism or if you consume 3 or more alcohol-containing drinks every day
  • if you have asthma, bleeding or clotting problems, growths in the nose (nasal polyps), kidney or liver problems, stomach or peptic ulcers (bleeding ulcers), heartburn, upset stomach, stomach pain, influenza (flu) or chicken pox, or vitamin K deficiency
  • if you are a child with a stroke, a weakened blood vessel (cerebral aneurysm) or bleeding in the brain, or Kawasaki syndrome (a rare inflammation causing heart problems in children)

Some MEDICINES MAY INTERACT with ZORprin Controlled-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Carbonic anhydrase inhibitors (eg, acetazolamide) because the effectiveness of ZORprin Controlled-Release Tablets may be decreased
  • Anticoagulants (eg, heparin, warfarin) or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, celecoxib) because side effects, including risk of bleeding, may be increased by ZORprin Controlled-Release Tablets
  • Insulin and oral antidiabetics (eg, glyburide, nateglinide) because side effects, including abnormally low blood sugar level (eg, hunger, shakiness or weakness, dizziness, headache, sweating), may be increased by ZORprin Controlled-Release Tablets
  • Methotrexate or valproic acid because their actions and side effects may be increased by ZORprin Controlled-Release Tablets
  • Angiotensin-converting enzyme inhibitors (eg, enalapril), probenecid, or sulfinpyrazone because their effectiveness may be decreased by ZORprin Controlled-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if ZORprin Controlled-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use ZORprin Controlled-Release Tablets:

Use ZORprin Controlled-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • ZORprin Controlled-Release Tablets may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Swallow ZORprin Controlled-Release Tablets whole. Do not break, crush, or chew before swallowing unless directed by your health care provider.
  • Take ZORprin Controlled-Release Tablets with a full glass of water.
  • Use ZORprin Controlled-Release Tablets exactly as directed on the package, unless instructed differently by your doctor. If you are taking ZORprin Controlled-Release Tablets without a prescription, follow any warnings and precautions on the label.
  • If you miss a dose of ZORprin Controlled-Release Tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use ZORprin Controlled-Release Tablets.

Important safety information:

  • ZORprin Controlled-Release Tablets contains aspirin. Before you begin taking any new prescription or over-the-counter medicine, read the ingredients to see if it also contains aspirin or an aspirin-like medicine. If it does or if you are uncertain, contact your doctor or pharmacist.
  • If you consume 3 or more alcohol-containing drinks every day, ask your doctor whether you should take ZORprin Controlled-Release Tablets or other pain relievers/fever reducers. ZORprin Controlled-Release Tablets may cause stomach bleeding. Alcohol use combined with ZORprin Controlled-Release Tablets may increase your risk for stomach bleeding.
  • ZORprin Controlled-Release Tablets may reduce the number of blood cells that are needed for clotting. To prevent bleeding, avoid situations where bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark tarry stools to your doctor.
  • ZORprin Controlled-Release Tablets contains aspirin, which has been linked to Reye syndrome. Do not give ZORprin Controlled-Release Tablets to children or teenagers during or after chicken pox, flu, or other viral infections without checking with your doctor, nurse, or pharmacist for more information.
  • If ZORprin Controlled-Release Tablets has a strong vinegar-like smell upon opening, do not use. It means the medicine is breaking down. Throw the bottle away safely and out of the reach of children; contact your pharmacist and replace.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using ZORprin Controlled-Release Tablets.
  • Do not take ZORprin Controlled-Release Tablets for at least 7 days after any surgery unless directed by your health care provider.
  • Do not take ZORprin Controlled-Release Tablets for more than 10 days for pain or for more than 3 days for fever unless directed to do so by your health care provider.
  • Diabetes patients-ZORprin Controlled-Release Tablets may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
  • Use ZORprin Controlled-Release Tablets with caution in the ELDERLY because they may be more sensitive to its effects, especially those with a blood coagulation disorder.
  • Safety in CHILDREN and instructions for use differs according to brand used. Talk to you doctor or pharmacist if you have any questions about the brand you are using.
  • PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using ZORprin Controlled-Release Tablets during pregnancy. ZORprin Controlled-Release Tablets is not recommended during the last 3 months (third trimester) of pregnancy due to the potential for fetal harm or complications during delivery. ZORprin Controlled-Release Tablets is excreted in breast milk. If you are or will be breast-feeding while you are using ZORprin Controlled-Release Tablets, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of ZORprin Controlled-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Heartburn; nausea; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; confusion; diarrhea; dizziness; drowsiness; hearing loss; ringing in the ears; severe stomach pain; vomiting.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include agitation; fever; hearing loss; lethargy; lightheadedness, especially upon standing; nausea; rapid breathing; rapid or irregular heartbeat; ringing in the ears; seizures; shortness of breath; stomach pain; vomiting.

Proper storage of ZORprin Controlled-Release Tablets:

Store ZORprin Controlled-Release Tablets at room temperature between 68 and 77 degrees F (20 and 25 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep ZORprin Controlled-Release Tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about ZORprin Controlled-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
  • ZORprin Controlled-Release Tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about ZORprin Controlled-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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