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Generic Name: Bromfenac (BROME-fen-ak)
Brand Name: Xibrom

Xibrom is used for:

Treating eye pain and swelling in patients who have recently had surgery to remove cataracts. It may also be used for other conditions as determined by your doctor.

Xibrom is a nonsteroidal anti-inflammatory drug (NSAID) eye drop. It works by blocking the production of prostaglandin, a substance that causes inflammation (redness, swelling, irritation).

Do NOT use Xibrom if:

  • you are allergic to any ingredient in Xibrom
  • you are in late pregnancy

Contact your doctor or health care provider right away if any of these apply to you.

Before using Xibrom :

Some medical conditions may interact with Xibrom . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to aspirin or any medicine containing aspirin, an NSAID (eg, ibuprofen), or a phenylacetic acid derivative
  • if you have asthma, diabetes, bleeding problems, or rheumatoid arthritis
  • if you have other eye problems (eg, dry eye syndrome, cornea problems), have had complicated eye surgery, or have had repeated eye surgeries within a short period of time

Some MEDICINES MAY INTERACT with Xibrom . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin) or heparin because the risk of bleeding may be increased
  • Corticosteroids (eg, prednisolone) because healing may be slowed or delayed

This may not be a complete list of all interactions that may occur. Ask your health care provider if Xibrom may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Xibrom :

Use Xibrom as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • To use Xibrom , wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
  • Do not wear contact lenses while you are using Xibrom . Sterilize contact lenses according to manufacturer"s directions and check with your doctor before using them.
  • If you miss a dose of Xibrom , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Xibrom .

Important safety information:

  • Do not exceed the recommended dose or take Xibrom for longer than prescribed without checking with your doctor.
  • If your symptoms do not improve within 14 days or if they become worse, check with your doctor.
  • Xibrom contains sulfites, which can cause allergic reactions in certain individuals (eg, asthma patients). If you have previously had allergic reactions to sulfites, contact your doctor or pharmacist before using Xibrom .
  • Use Xibrom with caution in CHILDREN younger than 18 years of age. Safety and efficacy in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Xibrom may cause harm to the fetus. If you become pregnant, discuss with your doctor the benefits and risks of using Xibrom during pregnancy. Avoid use of Xibrom during late pregnancy. It is unknown if Xibrom is excreted in breast milk. If you are or will be breast-feeding while you are using Xibrom , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Xibrom :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Eye burning, irritation, itching, pain, redness, stinging, or swelling; headache; unusual feeling in the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe eye burning, irritation, itching, redness, stinging, or swelling; unusual bleeding of the eye; vision changes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Xibrom :

Store Xibrom between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Xibrom out of the reach of children and away from pets.

General information:

  • If you have any questions about Xibrom , please talk with your doctor, pharmacist, or other health care provider.
  • Xibrom is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Xibrom . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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