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Vectibix, |Vectibix

Vectibix

Generic Name: panitumumab (pan i TUE moo mab)
Brand Names: Vectibix

What is panitumumab?

Panitumumab is a cancer medication. It interferes with the growth of cancer cells and slows their growth and spread in your body.

Panitumumab is used to treat metastatic colorectal cancer that has progressed after treatment with other chemotherapy.

Panitumumab may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about panitumumab?

Before receiving this medication, tell your doctor if you have any allergies or breathing problems. You may not be able to receive panitumumab, or you may need a dosage adjustment or special tests during treatment.

Some people receiving a panitumumab injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, itchy, short of breath, or if you have a fever or chills during the injection.

The side effects of panitumumab may not appear when you first start using the medication. Severe skin or eye reactions may occur up to 2 weeks after the start of your treatment. These effects may not clear up for weeks or even months after you stop receiving panitumumab.

This medication may affect a woman"s fertility (ability to have children). You may also have irregular menstrual periods while receiving panitumumab.

What should I discuss with my health care provider before receiving panitumumab?

Before receiving this medication, tell your doctor if you have any allergies or breathing problems. You may not be able to receive panitumumab, or you may need a dosage adjustment or special tests during treatment.

This medication may affect a woman"s fertility (ability to have children). You may also have irregular menstrual periods while receiving panitumumab.

How is panitumumab given?

Panitumumab is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take up to 90 minutes to complete.

Before you receive this medication, you may need to undergo a biopsy to make sure panitumumab is the right medication to treat your cancer.

Panitumumab is usually given once every 2 weeks. Follow your doctor"s instructions.

What happens if I miss a dose?

Contact your doctor if you miss an appointment for your panitumumab injection.

What happens if I overdose?

Seek emergency medical attention if you think you have received too much of this medicine. Symptoms of a panitumumab overdose are unknown.

What should I avoid while taking panitumumab?

Panitumumab side effects

Some people receiving a panitumumab injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, itchy, short of breath, or if you have a fever or chills during the injection.

Some of the side effects of panitumumab may not appear when you first start using the medication. Severe skin or eye reactions may occur up to 2 weeks after the start of your treatment. These effects may not clear up for weeks or even months after you stop receiving panitumumab.

• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

• swelling around your fingernails or toenails;

• acne, dryness, cracking, bleeding, oozing, pus, or any other sign of skin infection;

• cough or wheezing, running out of breath easily;

• white patches or sores inside your mouth or on your lips;

• drowsiness, restless feeling, confusion, muscle stiffness, fast or uneven heart rate, chest pain;

• redness, swelling, or irritation of your eyes or eyelids; or

• increased tearing of your eyes.

Less serious side effects are more likely to occur, such as:

• nausea, stomach pain;

• diarrhea or constipation; or

• tired feeling.

What other drugs will affect panitumumab?

There may be other drugs not listed that can affect panitumumab. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

• Your doctor has information about panitumumab written for health professionals that you may read.

What does my medication look like?

Panitumumab is available with a prescription under the brand name Vectibix Other brand or generic forms may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.