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Trovan, |Trovan Trovan

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Trovan

Generic Name: trovafloxacin (troe va FLOCKS ah sin)
Brand Names: Trovan

What is trovafloxacin?

Trovafloxacin has been withdrawn from the U.S. market.

Trovafloxacin is an antibiotic in the class of drugs called fluoroquinolones. It fights bacteria in the body.

Trovafloxacin is used to treat serious infections including pneumonia, complicated abdominal infections, gynecologic and pelvic infections, and skin infections.

Trovafloxacin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about trovafloxacin?

Trovafloxacin has been withdrawn from the U.S. market.

Rarely, trovafloxacin has been associated with the development of serious liver injury that has resulted in liver transplant and/or death. Stop taking trovafloxacin and consult your doctor immediately if you develop fatigue, decreased appetite, yellowing of the skin or eyes, severe stomach pain with nausea and vomiting, or dark urine. These may be early signs of liver damage. Avoid prolonged exposure to sunlight. Trovafloxacin can increase the sensitivity of the skin to sunlight. A severe sunburn may result, even with minimal sun exposure. If exposure to the sun is unavoidable, wear protective clothing and use sunscreen. Call your doctor if you experience severe burning, redness, itching, rash, or swelling after exposure to the sun. Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 2 hours before and 2 hours after a dose of trovafloxacin. These medicines decrease the effectiveness of trovafloxacin. Use caution when driving, operating machinery, or performing other hazardous activities. Trovafloxacin may cause dizziness. If you experience dizziness, avoid these activities.

What should I discuss with my healthcare provider before taking trovafloxacin?

Do not take trovafloxacin without first talking to your doctor if you have liver disease. You may not be able to take trovafloxacin, or you may require a dosage adjustment or special monitoring during your treatment. Trovafloxacin is in the FDA pregnancy category C. This means that it is not known whether trovafloxacin will be harmful to an unborn baby. Do not take trovafloxacin without first talking to your doctor if you are pregnant or could become pregnant during treatment. Trovafloxacin passes into breast milk and may harm a nursing infant by affecting bone development. Do not take trovafloxacin without first talking to your doctor if you are breast-feeding a baby. The safety and effectiveness of trovafloxacin in patients younger than 18 years of age has not been established. Children generally should not take trovafloxacin.

How should I take trovafloxacin?

Take trovafloxacin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water (8 ounces).

Trovafloxacin can be taken with or without food.

Take all of the trovafloxacin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 2 hours before and 2 hours after a dose of trovafloxacin. These medicines decrease the effectiveness of trovafloxacin. Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a trovafloxacin overdose include seizures, poor coordination, tremors, drooping eyelids, and slow breathing.

What should I avoid while taking trovafloxacin?

Avoid prolonged exposure to sunlight. Trovafloxacin can increase the sensitivity of the skin to sunlight. A severe sunburn may result, even with minimal sun exposure. If exposure to the sun is unavoidable, wear protective clothing and use sunscreen. Call your doctor if you experience severe burning, redness, itching, rash, or swelling after exposure to the sun. Use caution when driving, operating machinery, or performing other hazardous activities. Trovafloxacin may cause dizziness. If you experience dizziness, avoid these activities.

Trovafloxacin side effects

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
muscle or joint pain or inflammation.

If you experience any of the following less serious side effects, continue taking trovafloxacin and talk to your doctor:

dizziness or lightheadedness;
nausea, vomiting, or diarrhea;
abdominal pain;
headache;
itching or a rash; or
increased sensitivity of the skin to sunlight.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect trovafloxacin?

Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc, for a minimum of 2 hours before or 2 hours after a dose of trovafloxacin. These medicines decrease the effectiveness of trovafloxacin.

Also, morphine given intravenously (IV) may decrease the absorption of trovafloxacin. Generally, these two medicines should not be given at the same time.

Drugs other than those listed here may also interact with trovafloxacin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

Your pharmacist has additional information about trovafloxacin written for health professionals that you may read.

What does my medication look like?

Trovafloxacin has been withdrawn from the U.S. market.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 2.04. Revision Date: 2/22/07 3:00:07 PM.

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