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|Trimethoprim

Trimethoprim

Trimethoprim is used for:

Treating infections caused by certain bacteria.

Trimethoprim is an antibiotic. It works by killing sensitive bacteria.

Do NOT use Trimethoprim if:

• you are allergic to any ingredient in Trimethoprim or to similar medicines
• you are taking dofetilide
• you have anemia caused by low levels of folate in the blood

Contact your doctor or health care provider right away if any of these apply to you.

Before using Trimethoprim :

Some medical conditions may interact with Trimethoprim . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have liver or kidney problems or blood problems (eg, anemia, porphyria)
• if you have or are at risk for low levels of folate in the blood (eg, you have alcoholism, are elderly, you do not absorb nutrients from food properly, you are in a poor nutritional state, you are taking medicine for seizures)

Some MEDICINES MAY INTERACT with Trimethoprim . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Dofetilide because risk of severe heart problems may be increased by Trimethoprim
• Methotrexate, phenytoin, or sulfones (eg, dapsone) because actions and side effects may be increased by Trimethoprim
• Cyclosporine because effectiveness may be decreased and risk of liver side effects may be increased by Trimethoprim

This may not be a complete list of all interactions that may occur. Ask your health care provider if Trimethoprim may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Trimethoprim :

Use Trimethoprim as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Trimethoprim may be taken with or without food.
• Trimethoprim works best if taken at the same time every day.
• To clear up your infection completely, continue using Trimethoprim for the full course of treatment even if you feel better in a few days.
• If you miss a dose of Trimethoprim , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Trimethoprim .

Important safety information:

• Trimethoprim may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Trimethoprim . Use a sunscreen or protective clothing if you must be outside for a prolonged period.
• If severe diarrhea, stomach pain/cramps, or bloody stools occur, contact your doctor immediately. This could be a symptom of a serious side effect requiring immediate medical attention. Do not treat diarrhea without consulting your doctor.
• It is important to use Trimethoprim for the full course of treatment. Failure to do so may decrease the effectiveness of Trimethoprim and increase the risk that the bacteria will no longer be sensitive to Trimethoprim and will not be able to be treated by this or certain other antibiotics in the future.
• Trimethoprim is effective only against bacteria. It is not effective for treating viral infections (eg, the common cold).
• Long-term or repeated use of Trimethoprim may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.
• Trimethoprim may interfere with certain lab test results. Make sure your doctor and laboratory personnel know you are using Trimethoprim .
• LAB TESTS, including complete blood cell counts, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
• Use Trimethoprim with caution in ELDERLY patients because they may be more sensitive to the effects of Trimethoprim .
• Use Trimethoprim with extreme caution in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed.
• Use Trimethoprim with extreme caution in CHILDREN younger than 10 years of age who have diarrhea or a stomach or bowel infection.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Trimethoprim during pregnancy. Trimethoprim is excreted in breast milk. If you are or will be breastfeeding while you are using Trimethoprim , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Trimethoprim :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; skin sensitivity to sunlight; stomach upset; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blistered, peeling, red, or swollen skin; bloody or black, tarry stools; chest pain; chills, fever, or sore throat; decreased urination; joint or muscle pain; irregular heartbeat; painful or stiff neck; purple patches under the skin; seizures; severe diarrhea; shortness of breath; stomach cramps/pain; unusual bruising or bleeding; unusual tiredness or weakness; unusually pale skin; vaginal irritation or discharge; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include confusion; depression; dizziness; drowsiness; fever, chills, or sore throat; loss of consciousness; severe nausea or vomiting; severe or prolonged headache; unusual bruising or bleeding.

Store Trimethoprim at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Keep in a tight, light-resistant container. Do not store in the bathroom. Keep Trimethoprim out of the reach of children and away from pets.

General information:

• If you have any questions about Trimethoprim , please talk with your doctor, pharmacist, or other health care provider.
• Trimethoprim is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Trimethoprim . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.