Trasylol
 Trasylol

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|Trasylol Trasylol

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Trasylol


Generic Name: Aprotinin (app-row-TIE-nin)
Brand Name: Trasylol

Trasylol may cause severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; fast heartbeat, pale skin, a drop in blood pressure, and loss of consciousness possibly leading to lack of heartbeat or breathing). The risk is increased if you have previously received Trasylol .


Trasylol is used for:

Reducing blood loss and the need for blood transfusions in patients undergoing certain types of heart surgery.

Trasylol is a protease inhibitor. It works by reducing the inflammatory response associated with cardiopulmonary bypass surgery.

Do NOT use Trasylol if:

  • you are allergic to any ingredient in Trasylol

Contact your doctor or health care provider right away if any of these apply to you.

Before using Trasylol :

Some medical conditions may interact with Trasylol . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney problems
  • if you have previously had heart surgery or have used Trasylol before

Some MEDICINES MAY INTERACT with Trasylol . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Angiotensin-converting enzyme (ACE) inhibitors (eg, captopril) or fibrinolytics (eg, streptokinase) because the effectiveness of these medicines may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Trasylol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Trasylol :

Use Trasylol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Trasylol is administered as an intravenous (IV; into a vein) injection only in a medical setting.
  • Trasylol comes with an additional patient leaflet. Read it carefully and reread it each time you get Trasylol refilled.
  • If you miss a dose of Trasylol , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Trasylol .

Important safety information:

  • LAB TESTS may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Trasylol is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Trasylol during pregnancy. It is unknown if Trasylol is excreted in breast milk. If you are or will be breast-feeding while you are using Trasylol , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Trasylol :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; difficulty urinating; infection (fever, chills, sore throat); lightheadedness; sleeplessness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); asthma; chest pain; confusion; decreased urination; fast or irregular heartbeat; lung disorder; nausea; numbness of an arm or leg; one-sided weakness; severe stomach pain; sudden severe headache, dizziness, fainting, or vomiting; sudden weight gain; swelling of the hands, legs, or feet; vision or speech changes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800 -222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Trasylol :

Trasylol is usually handled and stored by a health care provider. Keep Trasylol out of the reach of children and away from pets.

General information:

  • If you have any questions about Trasylol , please talk with your doctor, pharmacist, or other health care provider.
  • Trasylol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Trasylol . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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