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|Trandolapril

Trandolapril

Trandolapril is used for:

Treatment of high blood pressure. It is also used to prevent hospitalization and improve survival after a heart attack in certain patients. It may be used alone or with other medicines. It may also be used for certain conditions as determined by your doctor.

Trandolapril is an angiotensin-converting enzyme (ACE) inhibitor. It works by decreasing a chemical that tightens blood vessels. This causes blood vessels to relax (dilate), which lowers blood pressure and decreases the workload on the heart.

Do NOT use Trandolapril if:

• you are allergic to any ingredient in Trandolapril or to any other ACE inhibitor (eg, enalapril)
• you have ever had an allergic reaction (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue) to any other ACE inhibitor (eg, captopril, lisinopril)
• you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Trandolapril :

Some medical conditions may interact with Trandolapril . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines or other substances
• if you have bone marrow depression, heart problems, high blood potassium levels, low blood sodium levels, kidney disease or transplant, an autoimmune disease, lupus, or thickening of the skin, or if you are having an allergic reaction
• if you are on a sodium-restricted diet
• if you have low blood volume, diarrhea, vomiting, or are undergoing dialysis

Some MEDICINES MAY INTERACT with Trandolapril . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Indomethacin, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, naproxen), or salicylates (eg, aspirin) because the effectiveness of Trandolapril may be decreased
• Indomethacin, loop diuretics (eg, furosemide), NSAIDs (eg, ibuprofen, naproxen), or thiazide-type diuretics (eg, hydrochlorothiazide) because the actions and side effects of Trandolapril may be increased
• Indomethacin, lithium, loop diuretics (eg, furosemide), NSAIDs (eg, ibuprofen, naproxen), potassium preparations (eg, potassium chloride), potassium-sparing diuretics (eg, spironolactone), sulfonylureas (eg, glipizide), thiazide-type diuretics (eg, hydrochlorothiazide), or trimethoprim because the actions and side effects of these medicines may be increased
• Loop diuretics (eg, furosemide) or thiopurines (eg, azathioprine) because the effectiveness of these medicines may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Trandolapril may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Trandolapril :

Use Trandolapril as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Trandolapril may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Taking Trandolapril at the same time each day will help you remember to take it.
• Do not take antacids within 1 hour before or 2 hours after taking Trandolapril .
• Do not take dextran sulfate within 2 hours of Trandolapril .
• Drink plenty of fluids while taking Trandolapril unless otherwise directed by your doctor. Not drinking enough fluids, or excessive sweating, diarrhea, or vomiting can lead to lightheadedness or fainting.
• If you miss a dose of Trandolapril , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Trandolapril .

Important safety information:

• Trandolapril may cause dizziness or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Trandolapril . Using Trandolapril alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Dizziness or lightheadedness may occur if you stand up too fast from a lying or sitting position. If this occurs, get up slowly and avoid sudden changes in posture. If lightheadedness occurs, especially during the first few days of treatment, contact your health care provider.
• Patients being treated for high blood pressure often feel tired or run down for a few weeks after starting blood pressure medicines. Continue taking your medicine even though you may not feel quite "normal." Contact your health care provider about any new symptoms.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Trandolapril .
• Do not use a salt substitute or a potassium supplement without checking with your doctor.
• Black patients are at higher risk for certain side effects, and may not respond as well to Trandolapril as patients of other races.
• LAB TESTS may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
• Trandolapril is not recommended for use in CHILDREN younger than 6 months of age. Safety and effectiveness in this age group have not been confirmed.
• PREGNANCY and BREAST-FEEDING: When Trandolapril is used after the third month of pregnancy, it can cause injury or even death to the developing fetus. Stop taking Trandolapril as soon as possible if you become pregnant. Trandolapril is excreted in breast milk. Do not breast-feed while taking Trandolapril .

Possible side effects of Trandolapril :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; fatigue; headache; indigestion; lightheadedness when sitting up or standing; muscle aches; nausea; persistent, dry cough; tiredness; vomiting; weakness.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fainting; fever; hoarseness; irregular or slow heartbeat; shortness of breath; sore throat; unusual stomach pain; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include dizziness; lightheadedness, especially upon standing; weakness.

Store Trandolapril at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Trandolapril out of the reach of children and away from pets.

General information:

• If you have any questions about Trandolapril , please talk with your doctor, pharmacist, or other health care provider.
• Trandolapril is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Trandolapril . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.