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Tolterodine tartrate

Generic name: Tolterodine tartrate
Brand names: Detrol LA, Detrol

Why is Tolterodine tartrate prescribed?

Tolterodine tartrate combats symptoms of overactive bladder, including frequent urination, urgency (increased need to urinate), and urge incontinence (inability to control urination). The drug works by blocking the nerve impulses that prompt the bladder to contract.

Most important fact about Tolterodine tartrate

In a limited number of people, Tolterodine tartrate causes blurred vision. Take care when driving or operating machinery until you know how the drug affects you.

How should you take Tolterodine tartrate?

Tolterodine tartrate can be taken with or without food. Swallow Tolterodine tartrate LA capsules whole.

--If you miss a dose...

Take the forgotten dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

--Storage instructions...

Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Tolterodine tartrate.

More common side effects may include:
Abdominal pain, blurred vision, constipation, diarrhea, dizziness, drowsiness, dry eyes, dry mouth, fatigue, flu-like symptoms, headache, indigestion, vertigo

Why should Tolterodine tartrate not be prescribed?

If you suffer from urinary retention (inability to urinate normally), gastric retention (a blockage in the digestive system), or uncontrolled narrow-angle glaucoma (high pressure in the eyes), you should not take Tolterodine tartrate. You should also avoid Tolterodine tartrate if it gives you an allergic reaction.

Special warnings about Tolterodine tartrate

Use Tolterodine tartrate with caution if you have a bladder obstruction or digestive disorder that could lead to a complete blockage. Use caution, too, if you are being successfully treated for glaucoma, or have a liver or kidney problem.

Possible food and drug interactions when taking Tolterodine tartrate

If you take Tolterodine tartrate with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Tolterodine tartrate with any of the following:

Clarithromycin (Biaxin)
Cyclosporine (Neoral, Sandimmune)
Erythromycin antibiotics such as Ery-Tab, Eryc, and PCE
Ketoconazole (Nizoral)
Itraconazole (Sporanox)
Miconazole
Vinblastine

Special information if you are pregnant or breastfeeding

The use of Tolterodine tartrate during pregnancy has not been adequately studied. If you are pregnant or plan to become pregnant while taking Tolterodine tartrate, tell your doctor immediately.

Researchers are not sure whether Tolterodine tartrate appears in breast milk. Use of the drug is not recommended while breastfeeding.

Recommended dosage

ADULTS

Tolterodine tartrate

The usual starting dosage is 2 milligrams twice a day. Your doctor may decrease the dose to 1 milligram twice a day if the higher dose causes problems. The 1-milligram dose is also recommended if you have liver problems or must take any of the drugs listed in the "Possible food and drug interactions" section above.

Tolterodine tartrate LA

The usual starting dosage is 4 milligrams taken once a day. Your doctor may cut the dose in half if it causes problems. A dose of 2 milligrams once daily is recommended for people with liver problems and those taking drugs that might interact.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect symptoms of an overdose with Tolterodine tartrate, seek medical attention immediately.

Symptoms of Tolterodine tartrate overdose may include:
Blurred vision, constipation, drowsiness, dry eyes, dry mouth

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