Tobrex Ointment

|Tobrex Ointment

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Tobrex Ointment

Generic Name: Tobramycin Eye Ointment (toe-bra-MYE-sin)
Brand Name: Tobrex

Tobrex Ointment is used for:

Treating eye infections.

Tobrex Ointment is an antibiotic. It works by killing or slowing the growth of certain types of bacteria.

Do NOT use Tobrex Ointment if:

  • you are allergic to any ingredient in Tobrex Ointment or to similar medicines

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tobrex Ointment:

Some medical conditions may interact with Tobrex Ointment. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Tobrex Ointment. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Cephalosporins by injection (eg, ceftazidime) because they may decrease Tobrex Ointment"s effectiveness
  • Cyclosporine, fludarabine, loop diuretics (eg, furosemide), methoxyflurane, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin), nitrosoureas (eg, streptozocin), polypeptide antibiotics (eg, polymyxin B), or vancomycin injection because they may increase the risk of Tobrex Ointment"s side effects, including increased risk of kidney or hearing problems
  • Cephalosporins by injection (eg, ceftazidime), nondepolarizing muscle relaxants (eg, pancuronium), or succinylcholine because the risk of their side effects may be increased by Tobrex Ointment

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tobrex Ointment may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tobrex Ointment:

Use Tobrex Ointment as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Remove contact lenses before you use Tobrex Ointment.
  • Do not wear contact lenses while you are using Tobrex Ointment. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.
  • Tobrex Ointment may be used around the eye or in the eye. To use Tobrex Ointment in the eye, first, wash your hands. Using your index finger, pull the lower eyelid away from your eye to form a pouch. Squeeze a thin strip of ointment into the pouch. After using Tobrex Ointment, gently close your eyes for 1 to 2 minutes. Wash your hands to remove any medicine that may be on them. Wipe the applicator tip with a clean, dry tissue.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
  • To clear up your infection completely, take/use Tobrex Ointment for the full course of treatment. Keep taking/using it even if you feel better in a few days.
  • Tobrex Ointment works best if it is used at the same time each day.
  • Do not miss any doses. If you miss a dose of Tobrex Ointment, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Tobrex Ointment.

Important safety information:

  • Tobrex Ointment may cause blurred vision. Use Tobrex Ointment with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly.
  • If your symptoms do not get better within a few days or if they get worse, check with your doctor.
  • Be sure to use Tobrex Ointment for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Tobrex Ointment may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Tobrex Ointment should not be used in CHILDREN younger than 2 months old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tobrex Ointment while you are pregnant. It is not known if Tobrex Ointment is found in breast milk. Do not breast-feed while using Tobrex Ointment.

Possible side effects of Tobrex Ointment:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; burning or stinging in the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; continued redness, burning, or itching of the eye or eyelid; eye pain.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include blurred vision; eye pain; eye watering; swelling and itching of the eyelid.

Proper storage of Tobrex Ointment:

Store Tobrex Ointment at room temperature, between 46 and 80 degrees F (8 and 27 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tobrex Ointment out of the reach of children and away from pets.

General information:

  • If you have any questions about Tobrex Ointment, please talk with your doctor, pharmacist, or other health care provider.
  • Tobrex Ointment is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tobrex Ointment. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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