Tobramycin/Dexamethasone Ointment

|Tobramycin/Dexamethasone Ointment

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Tobramycin/Dexamethasone Ointment

Generic Name: Tobramycin/Dexamethasone Eye Ointment (toe-bra-MYE-sin/dex-a-METH-a-sone)
Brand Name: TobraDex

Tobramycin/Dexamethasone Ointment is used for:

Treating eye inflammation and bacterial infection.

Tobramycin/Dexamethasone Ointment is an antibiotic (tobramycin) and steroid (dexamethasone) combination eye ointment. The antibiotic works by killing bacteria and the steroid reduces redness, irritation, and swelling.

Do NOT use Tobramycin/Dexamethasone Ointment if:

  • you are allergic to any ingredient in Tobramycin/Dexamethasone Ointment
  • you have herpes simplex, vaccine, varicella, or any other viral, mycobacterial, or fungal eye infection

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tobramycin/Dexamethasone Ointment:

Some medical conditions may interact with Tobramycin/Dexamethasone Ointment. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have thinning of the cornea or the white part of the eye
  • if you have diabetes

Some MEDICINES MAY INTERACT with Tobramycin/Dexamethasone Ointment. Because little, if any, of Tobramycin/Dexamethasone Ointment is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Tobramycin/Dexamethasone Ointment may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tobramycin/Dexamethasone Ointment:

Use Tobramycin/Dexamethasone Ointment as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Tobramycin/Dexamethasone Ointment is only for the eye. Do not get it in your nose or mouth.
  • To use Tobramycin/Dexamethasone Ointment in the eye, first, wash your hands. Using your index finger, pull the lower eyelid away from your eye to form a pouch. Squeeze a thin strip of ointment into the pouch. After using Tobramycin/Dexamethasone Ointment, gently close your eyes for 1 to 2 minutes. Wash your hands to remove any medicine that may be on them. Wipe the applicator tip with a clean, dry tissue.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
  • Do not wear contact lenses while you are using Tobramycin/Dexamethasone Ointment. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.
  • Using Tobramycin/Dexamethasone Ointment at the same time each day will help you to remember to use it.
  • To clear up your infection completely, use Tobramycin/Dexamethasone Ointment for the full course of treatment. Keep using it even if you feel better in a few days.
  • If you miss a dose of Tobramycin/Dexamethasone Ointment, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Tobramycin/Dexamethasone Ointment.

Important safety information:

  • Tobramycin/Dexamethasone Ointment may cause blurred vision. Use Tobramycin/Dexamethasone Ointment with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly.
  • If your symptoms do not improve within a few days or if they get worse, check with your doctor.
  • Be sure to use Tobramycin/Dexamethasone Ointment for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Tobramycin/Dexamethasone Ointment may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Do not use Tobramycin/Dexamethasone Ointment for future eye problems unless directed by your doctor.
  • Lab tests, including eye exams, may be performed while you use Tobramycin/Dexamethasone Ointment. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Tobramycin/Dexamethasone Ointment should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tobramycin/Dexamethasone Ointment while you are pregnant. It is not known if Tobramycin/Dexamethasone Ointment is found in breast milk. Do not breast-feed while taking Tobramycin/Dexamethasone Ointment.

Possible side effects of Tobramycin/Dexamethasone Ointment:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning or stinging when you first put the medicine in your eye; delayed wound healing.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; itching and swelling of the eyelid; redness or swelling of the eye; second infection; severe eye pain; vision loss.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include flushing; increased tearing; lid itching; redness; swelling; spots or lesions on the surface of the cornea.

Proper storage of Tobramycin/Dexamethasone Ointment:

Store Tobramycin/Dexamethasone Ointment between 46 and 80 degrees F (8 and 27 degrees C). Store upright in the original container and away from heat, moisture, and light. Do not store in the bathroom. Keep Tobramycin/Dexamethasone Ointment out of the reach of children and away from pets.

General information:

  • If you have any questions about Tobramycin/Dexamethasone Ointment, please talk with your doctor, pharmacist, or other health care provider.
  • Tobramycin/Dexamethasone Ointment is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tobramycin/Dexamethasone Ointment. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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