Tinidazole

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Tinidazole


Generic Name: Tinidazole (tie-NIH-dah-zole)
Brand Name: Tindamax

Similar medicines have caused cancer in lab animals. Although there have been no reports of cancer with Tinidazole , unnecessary use should be avoided.


Tinidazole is used for:

Treating infections caused by certain parasites.

Tinidazole is an antiprotozoal. Exactly how Tinidazole works is unknown.

Do NOT use Tinidazole if:

  • you are allergic to any ingredient in Tinidazole or to other nitroimidazole medicines (metronidazole)
  • you have the blood disease porphyria
  • you are in your first 3 months of pregnancy
  • you are taking busulfan, cisapride, or an H1 antagonist (eg, astemizole, terfenadine)
  • you have taken disulfiram within the past 2 weeks

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tinidazole :

Some medical conditions may interact with Tinidazole . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have nerve, brain, or blood problems; a yeast infection; or a history of seizures or liver problems
  • if you are undergoing dialysis

Some MEDICINES MAY INTERACT with Tinidazole . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), phenytoin, or rifampin because the effectiveness of Tinidazole may be decreased
  • Anticoagulants (eg, warfarin), busulfan, cisapride, cyclosporine, fluorouracil, H1 antagonists (eg, astemizole, terfenadine), lithium, macrolide immunosuppressants (eg, tacrolimus), or sulfonylureas (eg, glipizide) because the actions and side effects of these medicines may be increased
  • Disulfiram because side effects, such as mental or mood changes, may occur
  • Oral contraceptives (birth control pills) because their effectiveness may be decreased by Tinidazole

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tinidazole may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tinidazole :

Use Tinidazole as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Tinidazole with food.
  • If you take cholestyramine, do not take it at the same time you take Tinidazole . Talk with your doctor about how you should take cholestyramine with Tinidazole .
  • If more than one dose of Tinidazole is required, continue using Tinidazole for the full course of treatment in order to clear up your infection completely, even if you feel better in a few days. Do not miss any doses.
  • If you miss a dose of Tinidazole , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tinidazole .

Important safety information:

  • Tinidazole may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tinidazole . Using Tinidazole alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Avoid drinking alcohol or taking products that contain alcohol while taking Tinidazole and for 3 days after the last dose.
  • Tinidazole may discolor or darken the urine. This is normal and not a cause for concern.
  • Tinidazole may decrease the effectiveness of your birth control pill. To prevent pregnancy, be sure to use an additional form of birth control (eg, condoms) while using Tinidazole .
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Tinidazole .
  • Tinidazole may affect certain lab test results. Make sure your doctor and lab personnel know you are using Tinidazole .
  • LAB TESTS, including blood cell counts, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Tinidazole with extreme caution in CHILDREN younger than 3 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Tinidazole may cause harm to the fetus. Tinidazole should not be used during the first trimester of pregnancy. If you think you may be pregnant, discuss with your doctor the benefits and risks of using Tinidazole during pregnancy. Tinidazole is excreted in breast milk. Do not breast-feed while taking Tinidazole and for 3 days after you have taken the last dose.

Possible side effects of Tinidazole :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; general body discomfort; headache; loss of appetite; metallic/bitter taste in mouth; nausea; stomach pain; tiredness; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal skin sensations (prickling, tingling); depression; fever, chills, or persistent sore throat; hoarseness; irregular heartbeat; numbness or loss of feeling in the hands or feet; pounding in the chest; seizures; shortness of breath; unusual bruising or bleeding ; vaginal irritation or discharge.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Tinidazole :

Store Tinidazole at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tinidazole out of the reach of children and away from pets.

General information:

  • If you have any questions about Tinidazole , please talk with your doctor, pharmacist, or other health care provider.
  • Tinidazole is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tinidazole . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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