Tiludronate

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Tiludronate


Generic Name: Tiludronate (tye-LOO-droe-nate)
Brand Name: Skelid

Tiludronate is used for:

Treating adults with Paget disease. It may also be used for other conditions as determined by your doctor.

Tiludronate is a bisphosphonate. It works by slowing the resorption of bone and allowing new bone to be formed.

Do NOT use Tiludronate if:

  • you are allergic to any ingredient in Tiludronate
  • you have severe kidney problems or esophagus problems, including difficulty swallowing or a narrow or blocked esophagus
  • you are unable to stand or sit for at least 30 minutes

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tiludronate :

Some medical conditions may interact with Tiludronate . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have pain or burning upon swallowing, a stomach or intestinal disease, heartburn, chest pain, kidney problems, or low blood calcium levels

Some MEDICINES MAY INTERACT with Tiludronate . However, no specific interactions with Tiludronate are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tiludronate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tiludronate :

Use Tiludronate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Tiludronate is effective only if taken on an empty stomach. Do not take Tiludronate within 2 hours of eating or drinking.
  • Take Tiludronate with 6 to 8 ounces of plain water.
  • If you are also taking calcium or iron supplements, vitamins, antacids containing calcium, aspirin, or indomethacin, they may interfere with the absorption of Tiludronate . Do not take Tiludronate within 2 hours of these medicines.
  • If you are also taking aluminum or magnesium-containing products (eg, antacids), take them at least 2 hours after taking Tiludronate .
  • Continue to use Tiludronate even if you feel well. Do not miss any doses.
  • If you miss a dose of Tiludronate , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses on the same day.

Ask your health care provider any questions you may have about how to use Tiludronate .

Important safety information:

  • Tiludronate may cause drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tiludronate . Using Tiludronate alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Do not exceed the recommended dose or use Tiludronate for longer than prescribed without checking with your doctor.
  • Do not drink alcohol, smoke, or use other tobacco products while taking Tiludronate .
  • It is important to have enough calcium and vitamin D in your diet. Ask your doctor or pharmacist if you have questions about your diet or about taking dietary supplements such as calcium or vitamin D.
  • Talk to your doctor about weight-bearing exercises to increase the calcium density of bones.
  • LAB TESTS, including calcium levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Tiludronate with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Tiludronate during pregnancy. It is unknown if Tiludronate is excreted in breast milk. If you are or will be breast-feeding while you are using Tiludronate , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Tiludronate :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal skin sensations; diarrhea; gas; nausea; stomach upset; stuffy nose; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; chest pain; difficulty swallowing; pain upon swallowing; new, worsening, or severe heartburn; red swollen, blistered, or peeling skin; stomach pain; swelling of the hands or feet; throat pain or irritation; vision changes; vomit that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Do not lie down. Symptoms may include heartburn; pain upon swallowing; stomach upset or pain; ulcers.

Proper storage of Tiludronate :

Store Tiludronate at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tiludronate out of the reach of children and away from pets.

General information:

  • If you have any questions about Tiludronate , please talk with your doctor, pharmacist, or other health care provider.
  • Tiludronate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tiludronate . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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