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|Tikosyn

Tikosyn

Tikosyn is used for:

Maintaining normal heart rhythm in patients with certain irregular heart rhythms. It may also be used for other conditions as determined by your doctor.

Tikosyn is an antiarrhythmic. It works by blocking certain heart currents, which allows the heart to regain a normal rhythm.

Do NOT use Tikosyn if:

• you are allergic to any ingredient in Tikosyn
• you have severe kidney disease or an irregular heartbeat due to QT prolongation
• you are taking cimetidine, hydrochlorothiazide, itraconazole, ketoconazole, megestrol acetate, prochlorperazine, trimethoprim, or verapamil

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tikosyn :

Some medical conditions may interact with Tikosyn . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart conduction or rhythm problems, kidney disease, severe liver disease, or low magnesium or potassium levels in your blood

Some MEDICINES MAY INTERACT with Tikosyn . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Bepridil, cimetidine, cisapride, class I or III antiarrhythmics (eg, amiodarone, sotalol), diuretics (eg, furosemide), hydrochlorothiazide, itraconazole, ketoconazole, ketolides (eg, telithromycin), macrolides (eg, erythromycin), megestrol acetate, phenothiazines (eg, thioridazine), prochlorperazine, progestins (eg, medroxyprogesterone), quinolones (eg, sparfloxacin, grepafloxacin), tricyclic antidepressants (eg, amitriptyline), trimethoprim, or verapamil because they increase the risk of life-threatening irregular heart rhythms

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tikosyn may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tikosyn :

Use Tikosyn as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Tikosyn may be taken with or without food.
• Tikosyn comes with an additional patient leaflet. Read it carefully and reread it each time you get Tikosyn refilled.
• Take Tikosyn at the same time each day.
• Continue to use Tikosyn even if you feel well. Do not miss any doses.
• If you miss a dose of Tikosyn , skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tikosyn .

Important safety information:

• Tikosyn may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tikosyn . Using Tikosyn alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Tikosyn .
• Do not use a salt substitute or a potassium supplement without checking with your doctor.
• LAB TESTS, including electrocardiograms (ECG), kidney function, and potassium and magnesium blood tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• Use Tikosyn with caution in the ELDERLY because they may be more sensitive to its effects.
• Tikosyn is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Tikosyn during pregnancy. It is unknown if Tikosyn is excreted in breast milk. Do not breast-feed while taking Tikosyn .

Possible side effects of Tikosyn :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; nausea; respiratory tract infection.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark urine; difficulty breathing; fast, slow, or irregular heartbeat; fainting; heart attack; pale stool; paralysis; pounding in the chest; stopping of the heart; sudden death; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Store Tikosyn at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tikosyn out of the reach of children and away from pets.

General information:

• If you have any questions about Tikosyn , please talk with your doctor, pharmacist, or other health care provider.
• Tikosyn is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tikosyn . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.