Tigan Solution

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Tigan Solution


Generic Name: Trimethobenzamide Injection Solution (try-meth-oh-BEN-za-mide)
Brand Name: Tigan

Tigan Solution is used for:

Treating nausea and vomiting.

Tigan Solution is an antiemetic. It works by blocking one of the chemical messengers that stimulates nausea and vomiting.

Do NOT use Tigan Solution if:

  • you are allergic to any ingredient in Tigan Solution
  • you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tigan Solution:

Some medical conditions may interact with Tigan Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a brain disease, dehydration, electrolyte disturbance, fever, stomach or intestinal/bowel irritation, or Reye syndrome

Some MEDICINES MAY INTERACT with Tigan Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Ethanol (alcohol-containing beverages or medicines) because side effects, such as increased drowsiness, may occur
  • Sodium oxybate (GHB) because side effects such as drowsiness and increased sleep duration may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tigan Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tigan Solution:

Use Tigan Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Tigan Solution is usually administered as an injection at your doctor"s office, hospital, or clinic. If you are using Tigan Solution at home, carefully follow the injection procedures taught to you by your health care provider.
  • If Tigan Solution contains particles, is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Keep this product, as well as syringes and needles, out of the reach of children. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of Tigan Solution and you are taking it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Tigan Solution.

Important safety information:

  • Tigan Solution may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tigan Solution. Using Tigan Solution alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Tigan Solution. Tigan Solution will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • If your symptoms do not improve within a few days or if they become worse, check with your doctor.
  • Do not use Tigan Solution for future conditions without checking with your doctor.
  • Use Tigan Solution with caution in ELDERLY patients because they may be more sensitive to the effects of Tigan Solution.
  • Do not give CHILDREN Tigan Solution to treat vomiting when the cause of vomiting is unknown. Tigan Solution may contribute to the development of Reye syndrome, a rare but serious illness.
  • PREGNANCY and BREAST-FEEDING: It is unknown if Tigan Solution is excreted in breast milk. If you are or will be breast-feeding while you are using Tigan Solution, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Tigan Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; depression; diarrhea; disorientation; dizziness; drowsiness; headache; muscle cramps; pain, redness, or swelling at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; fever; loss of balance; seizures; shuffling walk; sore throat; uncontrolled movements of the arms or legs; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Tigan Solution:

Store Tigan Solution at room temperature (77 degrees F; 25 degrees C), away from heat, moisture, and light. Do not store in the bathroom. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Keep Tigan Solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Tigan Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Tigan Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tigan Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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