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|Thorazine Suppositories

Thorazine Suppositories

Thorazine Suppositories is used for:

Treating the manic phase of manic-depressive disorder, schizophrenia, anxiety and restlessness before surgery, tetanus, porphyria, severe behavioral and conduct disorders in children, nausea and vomiting, and severe hiccups. It may be used for other conditions as determined by your doctor.

Thorazine Suppositories is a phenothiazine. It works by blocking one of the chemical messengers (dopamine) in the brain. This helps to treat certain mental disorders or prevents or reduces nausea and vomiting due to medicines, chemicals, and some diseases.

Do NOT use Thorazine Suppositories if:

• you are allergic to any ingredient in Thorazine Suppositories
• you are in a state of impaired consciousness, unresponsiveness, or coma
• you are taking antihistamines (eg, astemizole, terfenadine), antiarrhythmic agents (eg, quinidine, flecainide), cisapride, dofetilide, fluoroquinolones (eg, ciprofloxacin), pimozide, streptogramins (eg, quinupristin), or ziprasidone

Contact your doctor or health care provider right away if any of these apply to you.

Before using Thorazine Suppositories:

Some medical conditions may interact with Thorazine Suppositories. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have or have ever had alcoholism or if you consume more than 3 alcoholic drinks per day
• if you have increased pressure in the eyes, glaucoma, or are at risk for glaucoma
• if you have a blood diseases, enlargement of the prostate gland, epilepsy or seizures, heart problems, low blood pressure, liver problems, chronic breathing or lung problems, Parkinson disease, or Reye syndrome

Some MEDICINES MAY INTERACT with Thorazine Suppositories. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticholinergics (eg, diphenhydramine, oxybutynin, scopolamine) or anticoagulants (eg, warfarin) because the effectiveness of Thorazine Suppositories may be decreased
• Antihistamines (eg, astemizole, terfenadine), antiarrhythmic agents (eg, quinidine, flecainide), beta-blockers (eg, propranolol), cisapride, dofetilide, droperidol, fluoroquinolones (eg, ciprofloxacin), haloperidol, ketolides (eg, telithromycin), macrolide antibiotics (eg, erythromycin), pimozide, streptogramins (eg, quinupristin), or ziprasidone because side effects such as racing heartbeat, dizziness, fainting, and life-threatening irregular heartbeat leading to unconsciousness may increase by Thorazine Suppositories
• Epinephrine, hydantoins (eg, phenytoin), meperidine, thiazide diuretics (eg, hydrochlorothiazide), or tricyclic antidepressants (eg, amitriptyline) because side effects may be increased by Thorazine Suppositories
• Guanethidine, levodopa, or pergolide because effectiveness may be decreased by Thorazine Suppositories

This may not be a complete list of all interactions that may occur. Ask your health care provider if Thorazine Suppositories may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Thorazine Suppositories:

Use Thorazine Suppositories as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• If the suppository is too soft to use, put it in the refrigerator for about 15 minutes or run cold water over it. Then remove the wrapper and moisten the suppository with cool water. Lie down on your side. Use your finger to push the pointed end of the suppository well up into the rectum.
• Wash your hands thoroughly after using Thorazine Suppositories.
• If you miss a dose of Thorazine Suppositories, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Thorazine Suppositories.

Important safety information:

• Thorazine Suppositories may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Thorazine Suppositories. Using Thorazine Suppositories alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Thorazine Suppositories. Thorazine Suppositories will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
• Alcohol, hot weather, exercise, and fever can increase the risk of dizziness, light-headedness, or fainting. To prevent these effects, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, light-headedness, or weakness.
• Do not become overheated in hot weather or during exercise or other activities because heatstroke may occur.
• Thorazine Suppositories may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Thorazine Suppositories. Use a sunscreen or protective clothing if you must be outside for a prolonged period.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Thorazine Suppositories.
• Involuntary and uncontrollable movements may develop with use of Thorazine Suppositories. Occurrence is highest among the elderly, especially women. The risk of developing these involuntary movements and the likelihood they will become permanent are increased with long-term use and with high doses. However, it is possible to develop these symptoms after short-term treatment at low doses. Contact your doctor at once if any of the following occur: involuntary movements of tongue, face, mouth, or jaw (eg, sticking out of the tongue, puffing of cheeks, puckering of mouth, chewing movements), or involuntary movements of the arms and legs.
• Neuroleptic malignant syndrome (NMS) is a serious side effect associated with Thorazine Suppositories. Symptoms include increased body heat; muscle rigidness; altered mental abilities, including lack of response to your surroundings; irregular or fast heartbeat; or sweating. Contact your doctor at once if any of these symptoms occur.
• Thorazine Suppositories may cause false-positive phenylketonuria (PKU) test results.
• LAB TESTS may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• Use Thorazine Suppositories with caution in the ELDERLY because they may be more sensitive to its effects, especially dizziness, light-headedness (especially upon standing), rapid heartbeat, breathing problems, urinary retention, and constipation.
• Thorazine Suppositories is not recommended for use in CHILDREN younger than 6 months of age. Safety and effectiveness in this age group have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Thorazine Suppositories during pregnancy. Thorazine Suppositories is excreted in breast milk. Do not breast-feed while taking Thorazine Suppositories.

If you suddenly stop taking Thorazine Suppositories, you may experience WITHDRAWAL symptoms, including nausea, vomiting, dizziness, and tremors.

Possible side effects of Thorazine Suppositories:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Agitation; blurred vision; constipation; dizziness; drowsiness; dry mouth; enlarged pupils; excessive hunger, thirst, or urination; fever; jitteriness; nausea; neck spasms; sensitivity to light; sexual problems; sleeplessness; stomach pain; stuffy nose; urination problems.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in breasts; changes in menstrual period; difficulty swallowing; drooling; fast or irregular heartbeat; inability to move eyes; increased body heat; infection (fever, chills, sore throat); involuntary movements of the arms and legs; involuntary movements of tongue, face, mouth, or jaw (eg, sticking out of tongue, puffing of cheeks, puckering of mouth, lip-smacking, chewing movements); mask-like face; mental changes, including lack of response to your surroundings; muscle restlessness; muscle spasms; prolonged or painful erection; restlessness; seizures; shuffling walk; stiff or rigid muscles; sweating; tension in legs; unusual eye movements; weakness of arms or legs; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include deep sleep or loss of consciousness; muscle spasms; restlessness; seizures; tremors; twitching.

Store Thorazine Suppositories at room temperature between 59 and 86 degrees F (15 and 30 degrees C), away from heat, moisture, and light. Do not store in the bathroom. Keep Thorazine Suppositories out of the reach of children and away from pets.

General information:

• If you have any questions about Thorazine Suppositories, please talk with your doctor, pharmacist, or other health care provider.
• Thorazine Suppositories is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Thorazine Suppositories. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.