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|Teslac

TESTOLACTONE (Systemic)†

Some commonly used brand names are:

In the U.S.—

• Teslac

† Not commercially available in Canada.

Category

• Antineoplastic

Description

Testolactone (tess-toe-LAK-tone) belongs to the general group of medicines called antineoplastics. It is used to treat some cases of breast cancer in females.

Testolactone is available only with your doctor"s prescription, in the following dosage form:

• Oral
• Tablets (U.S.)

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For testolactone, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to testolactone.

Pregnancy—Studies have not been done in humans. However, studies in rats at doses 2.5 to 7.5 times the human dose have shown that testolactone causes an increase in the number of fetus and infant deaths and abnormal growth.

Breast-feeding—It is not known whether testolactone passes into breast milk. However, this medicine has not been reported to cause problems in nursing babies.

Older adults—Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of testolactone in the elderly with use in other age groups.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems—The presence of other medical problems may affect the use of testolactone. Make sure you tell your doctor if you have any other medical problems, especially:

• Heart or kidney disease

Proper Use of This Medicine

Use this medicine only as directed by your doctor . Do not use more or less of it, and do not use it more often than your doctor ordered. The exact amount of medicine you need has been carefully worked out. Taking too much may increase the chance of side effects, while taking too little may not improve your condition.

Testolactone sometimes causes nausea and vomiting. However, it may have to be taken for several weeks or months to be effective. Even if you begin to feel ill, do not stop using this medicine without first checking with your doctor . Ask your health care professional for ways to lessen these effects.

If you vomit shortly after taking a dose of testolactone, check with your doctor. You will be told whether to take the dose again or to wait until the next scheduled dose.

Dosing—The dose of testolactone will be different for different patients. The dose that is used may depend on a number of things, including what the medicine is being used for and whether or not other medicines are also being taken. If you are taking testolactone at home, follow your doctor"s orders or the directions on the label . If you have any questions about the proper dose of testolactone, ask your doctor.

Missed dose—If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you miss two or more doses in a row, check with your doctor.

Storage—To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Revised: 09/30/1997

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