Tenoretic

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Tenoretic


Generic Name: Atenolol/Chlorthalidone (ay-TEN-oh-lol/klor-THAL-i-done)
Brand Name: Tenoretic

Tenoretic is used for:

Treating high blood pressure.

Tenoretic is a beta-blocker and diuretic combination. It works by interfering with certain body chemicals that cause the heart to beat with less force and pump out less blood. This allows the heart to beat more slowly and regularly. By blocking these chemicals, blood vessels are relaxed and widened, allowing blood pressure to decrease. The diuretic works by causing the kidney to eliminate larger-than-normal amounts of water.

Do NOT use Tenoretic if:

  • you are allergic to any ingredient in Tenoretic or to any other sulfonamide, such as acetazolamide, celecoxib, hydrochlorothiazide, glyburide, probenecid, sulfamethoxazole, or zonisamide
  • you have congestive heart failure that has not been treated, a very slow heartbeat, heart block, or inability to urinate
  • you are currently taking mibefradil

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tenoretic :

Some medical conditions may interact with Tenoretic . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have an untreated adrenal gland tumor, diabetes, gout, liver problems, overactive thyroid, or systemic lupus erythematosus (SLE; lupus)
  • if you have a history of severe allergic reactions to allergens, asthma, chronic bronchitis, chronic obstructive pulmonary disease, emphysema, or other lung disease; congestive heart failure, slow heartbeat, heart rhythm problems, or narrowing of blood vessels of the legs, arms, stomach, or kidneys; kidney problems; or low blood potassium or low blood sodium
  • if you are scheduled to have surgery or to receive anesthesia

Some MEDICINES MAY INTERACT with Tenoretic . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Disopyramide, indomethacin, or stimulants (eg, pseudoephedrine) because they may decrease Tenoretic "s effectiveness
  • Antiarrhythmics (eg, amiodarone, lidocaine, quinidine), bupivacaine, calcium channel blockers (eg, verapamil), digitalis (eg, digoxin), flecainide, ketanserin, mefloquine, or mibefradil because potentially life-threatening toxic effects on the heart may occur
  • Alpha-blockers (eg, doxazosin), diazoxide, lithium, or reserpine because the risk of their side effects may be increased by Tenoretic
  • Clonidine because excessive increases in blood pressure may occur, especially when stopping clonidine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tenoretic may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tenoretic :

Use Tenoretic as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Tenoretic by mouth with or without food.
  • Taking Tenoretic at the same time each day will help you remember to take it.
  • Continue to use Tenoretic even if you feel well. Do not miss any doses.
  • Tenoretic may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
  • If you miss a dose of Tenoretic , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tenoretic .

Important safety information:

  • Tenoretic may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Tenoretic with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Tenoretic may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Tenoretic may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Tenoretic . Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal". Tell your doctor if you develop any new symptoms.
  • Diabetes patients-Tenoretic may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you more hungry. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Tell your doctor or dentist that you take Tenoretic before you receive any medical or dental care, emergency care, or surgery.
  • Your doctor may have also prescribed a potassium supplement for you. If so, follow the dosing carefully. Do not start taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor.
  • Do not suddenly stop taking Tenoretic . Sharp chest pain, irregular heartbeat, and sometimes heart attack may occur if you suddenly stop Tenoretic . The risk may be greater if you have certain types of heart disease. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. This should be done even if you only take Tenoretic for high blood pressure. Heart disease is common and you may not know you have it. Limit physical activity while you are lowering your dose. If new or worsened chest pain or other heart problems occur, contact your doctor right away. You may need to start taking Tenoretic again.
  • Lab tests, such as electrolyte and blood pressure monitoring, may be performed while you use Tenoretic . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Tenoretic should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Tenoretic has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tenoretic while you are pregnant. Tenoretic is found in breast milk. If you are or will be breast-feeding while you use Tenoretic , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tenoretic :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; feeling of a whirling motion; headache; lack of energy; lightheadedness; mild drowsiness; nausea; unusual tiredness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty breathing; drowsiness; dry mouth; infrequent urination; lethargy; low blood pressure; muscle pain or cramps; muscle tiredness; nausea; rapid or irregular heartbeat; restlessness; thirst; very slow heartbeat; vomiting; weakness.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include altered mental status, confusion, or coma; coughing; difficulty in breathing, especially when lying down; dizziness; fainting; lightheadedness, especially upon standing; muscle weakness; seizures (convulsions); shortness of breath; very slow heart rate; wheezing.

Proper storage of Tenoretic :

Store Tenoretic at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tenoretic out of the reach of children and away from pets.

General information:

  • If you have any questions about Tenoretic , please talk with your doctor, pharmacist, or other health care provider.
  • Tenoretic is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is summary only. It does not contain all information about Tenoretic . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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