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Solage, |Solage Solag?

Solage

Generic Name: mequinol and tretinoin topical (MEH quih nall and TREH tih noyn)
Brand Names: Solage

What is mequinol and tretinoin topical?

Mequinol stops the action of chemicals in the skin that create pigmentation or darkening. Tretinoin is a topical form of vitamin A. It helps the skin to renew itself more quickly and also reduces pigmentation.

Mequinol and tretinoin topical is used to treat solar lentigines, also known as brown "age" or "liver" spots.

Mequinol and tretinoin topical may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about mequinol and tretinoin topical?

What should I discuss with my healthcare provider before using mequinol and tretinoin topical?

Before using mequinol and tretinoin topical, tell your doctor if you

• have a history, or a family history, of vitiligo (white patches of skin);

• have eczema;

• take prescription medications; or

• are using other topical products with a strong drying effect on the skin, products with high concentrations of alcohol, astringents, spices or lime, medicated soaps or shampoos, permanent wave solutions, electrolysis, hair removal products or waxes, or other preparations or processes that my dry or irritate your skin.

You may not be able to use mequinol and tretinoin topical, or you may need a dosage adjustment or special monitoring during treatment.

How should I use mequinol and tretinoin topical?

Use mequinol and tretinoin topical exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Apply mequinol and tretinoin topical using the applicator provided with the medication. Apply only enough to make the spot appear moist. Avoid applying so much medication that it runs or drips. Avoid getting the medication on the surrounding, normally colored skin. Do not shower or bathe the treated areas for at least 6 hours after application of mequinol and tretinoin topical.

Mequinol and tretinoin topical is usually applied twice daily, at least eight hours apart. Follow your doctor"s instructions.

Cosmetics may be applied 30 minutes after applying a dose of mequinol and tretinoin topical.

Mequinol and tretinoin topical is flammable. Keep it away from heat or open flame.

What happens if I miss a dose?

Skip the missed dose of mequinol and tretinoin topical. Do not try to make it up. Return to your normal application schedule as soon as you can.

What happens if I overdose?

An overdose of this medication is unlikely to be harmful. If you do suspect an overdose, or if mequinol and tretinoin topical has been ingested, call an emergency room or poison control center near you.

What should I avoid while using mequinol and tretinoin topical?

Avoid using other topical products on the same area at the same time unless directed to do so by your doctor. Use caution and talk to your doctor before using mequinol and tretinoin topical if you are also using other topical products with a strong drying effect on the skin, products with high concentrations of alcohol, astringents, spices or lime, medicated soaps or shampoos, permanent wave solutions, electrolysis, hair removal products or waxes, or other preparations or processes that my dry or irritate your skin.

Cosmetics may be applied 30 minutes after applying a dose of mequinol and tretinoin topical.

Mequinol and tretinoin topical side effects

Stop using mequinol and tretinoin topical and contact your doctor regarding continued treatment if the age spots you are treating become darker with treatment, or if they become the same color or lighter than your normally colored skin.

You may experience some burning, stinging, tingling, itching, redness, dryness, peeling, crusting, rash, irritation, or lightening of the skin surrounding the spot being treated while using mequinol and tretinoin topical. If these side effects are excessive, talk to your doctor. You may need a lower dose or less frequent applications of mequinol and tretinoin topical.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect mequinol and tretinoin topical?

• a diuretic (water pill) such as hydrochlorothiazide (HCTZ, HydroDiuril, Esidrix, Oretic, Microzide, others), chlorthalidone (Hygroton, Thalitone), chlorothiazide (Diuril), indapamide (Lozol), metolazone (Mykrox, Zaroxolyn), and others ;

• a tetracycline antibiotic such as tetracycline (Sumycin, Achromycin), minocycline (Minocin), doxycycline (Monodox, Doryx, Vibramycin, Vibra-Tabs), and others;

• a fluoroquinolone antibiotic such as enoxacin (Penetrex), lomefloxacin (Maxaquin), ciprofloxacin (Cipro), norfloxacin (Noroxin), and ofloxacin (Floxin);

• a sulfa drug (sulfonamide) such as sulfamethoxazole (Gantanol, others), sulfamethoxazole and trimethoprim (Bactrim, Cotrim, Septra, Septra DS, others), sulfisoxazole (Gantrisin), and others; or

• a phenothiazine including chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), thioridazine (Mellaril), and others.

The drugs listed above may make your skin more sensitive to sunlight. You may not be able to use mequinol and tretinoin topical, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Avoid using other topical products on the same area at the same time unless directed to do so by your doctor. Use caution and talk to your doctor before using mequinol and tretinoin topical if you are also using other topical products with a strong drying effect on the skin, products with high concentrations of alcohol, astringents, spices or lime, medicated soaps or shampoos, permanent wave solutions, electrolysis, hair removal products or waxes, or other preparations or processes that my dry or irritate your skin.

Drugs other than those listed here may also interact with mequinol and tretinoin topical. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

• Your pharmacist has additional information about mequinol and tretinoin topical written for health professionals that you may read.

What does my medication look like?

Mequinol and tretinoin topical is available with a prescription under the brand name Solage in a 2% mequinol and 0.01% tretinoin topical solution. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.