Septra Suspension

|Septra Suspension

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Septra Suspension

Generic Name: Sulfamethoxazole/Trimethoprim Suspension (sul-fa-meth-OX-a-zole/trye-METH-oh-prim)
Brand Name: Septra

Septra Suspension is used for:

Treating infections caused by certain bacteria.

Septra Suspension is an antibiotic combination containing a sulfonamide antibiotic. It works by killing sensitive bacteria.

Do NOT use Septra Suspension if:

  • you are allergic to any ingredient in Septra Suspension or to similar medicines
  • you had a severe allergic reaction to any other sulfonamide (sulfa) medicine (eg, glipizide, hydrochlorothiazide)
  • you are taking dofetilide
  • you have anemia caused by low levels of folate in the blood or urinary blockage
  • you are in week 38 of pregnancy or later (full-term) or you are breast-feeding
  • the patient is a child younger than 2 months old

Contact your doctor or health care provider right away if any of these apply to you.

Before using Septra Suspension:

Some medical conditions may interact with Septra Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription (especially seizure medications) or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver or kidney problems, blood problems (eg, anemia, porphyria), asthma, or AIDS
  • if you have severe allergies, glucose-6-phosphate dehydrogenase deficiency, or an enzyme deficiency
  • if you at risk for low levels of folate in the blood (eg, you have alcoholism, are elderly, you do not absorb nutrients from food properly, you are in a poor nutritional state, you are taking medicine for seizures)

Some MEDICINES MAY INTERACT with Septra Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Leucovorin because it may decrease Septra Suspension"s effectiveness
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, hydrochlorothiazide) because they may increase the risk of Septra Suspension"s side effects
  • Anticoagulants (eg, warfarin) because the risk of bleeding may be increased
  • Dofetilide because the risk of severe heart problems may be increased
  • Digoxin, methotrexate, phenytoin, sulfones (eg, dapsone), or sulfonylureas (eg, glipizide) because their actions and side effects may be increased
  • Cyclosporine because its effectiveness may be decreased and the risk of liver side effects may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Septra Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Septra Suspension:

Use Septra Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Septra Suspension by mouth with or without food.
  • Shake well before each use.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Septra Suspension works best if it is taken at the same time each day.
  • Take Septra Suspension with a full glass of water (8 oz/240 mL). Drink several extra glasses of water a day unless otherwise directed by your doctor.
  • To clear up your infection completely, take Septra Suspension for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you miss a dose of Septra Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Septra Suspension.

Important safety information:

  • Septra Suspension may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Septra Suspension. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Be sure to use Septra Suspension for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Septra Suspension only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Long-term or repeated use of Septra Suspension may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Diabetes patients - Septra Suspension may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Septra Suspension may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Septra Suspension.
  • Lab tests, including complete blood cell counts and kidney function tests, may be performed while you use Septra Suspension. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Septra Suspension with caution in the ELDERLY; they may be more sensitive to its effects, especially severe skin reactions, bone marrow suppression, or high blood potassium levels.
  • Use Septra Suspension with extreme caution in CHILDREN younger than 10 years old who have diarrhea or an infection of the stomach or bowel.
  • Septra Suspension should not be used in CHILDREN younger than 3 months old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Septra Suspension while you are pregnant. Do not use Septra Suspension if you are in week 38 of pregnancy or later (full-term). Septra Suspension is found in breast milk. Do not breast-feed while taking Septra Suspension.

Possible side effects of Septra Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Appetite loss; diarrhea; nausea; skin sensitivity to sunlight; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blistered, peeling, red, or swollen skin; bloody or black, tarry stools; chest pain; chills, fever, or sore throat; decreased urination; depression; hallucinations; irregular heartbeat; joint or muscle pain; painful or stiff neck; purple patches under the skin; seizures; severe diarrhea; severe or persistent cough; severe or persistent headache; severe or persistent nausea or vomiting; shortness of breath; stomach cramps/pain; unusual bruising or bleeding; unusual tiredness or weakness; unusually pale skin; vaginal irritation or discharge; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include blood in urine; confusion; depression; dizziness; drowsiness; loss of consciousness; severe nausea or vomiting; severe or prolonged headache; unusual bruising or bleeding.

Proper storage of Septra Suspension:

Store Septra Suspension at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Keep in a tight, light-resistant container. Do not store in the bathroom. Keep Septra Suspension out of the reach of children and away from pets.

General information:

  • If you have any questions about Septra Suspension, please talk with your doctor, pharmacist, or other health care provider.
  • Septra Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Septra Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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