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Emsam, |selegiline transdermal Selegiline

selegiline

Generic Name: selegiline (transdermal) (se LE ji leen)
Brand Names: Emsam

What is selegiline transdermal?

Selegiline prevents the breakdown of chemicals in the brain that are often imbalanced in people with depression.

Selegiline transdermal is used to treat major depressive disorder.

Selegiline may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about selegiline transdermal?

There are many other medicines that can cause serious medical problems if you take them while using selegiline. Tell your doctor about all other prescription and over-the-counter medications you use, including vitamins, minerals, and herbal products.

You should become very familiar with the list of foods to avoid while you are using selegiline.

You may have suicidal thoughts or behavior when you first start using this medication, especially if you are under 18 years old. Watch for worsening symptoms of depression or suicidal thoughts. Your doctor should check you at regular visits during your treatment.

What should I discuss with my health care provider before using selegiline transdermal?

• carbamazepine (Tegretol) or oxcarbazepine (Trileptal);

• cyclobenzaprine (Flexeril);

• dextromethorphan (cough medicine);

• meperidine (Demerol), propoxyphene (Darvon, Darvocet), or tramadol (Ultram, Ultracet);

• methadone (Dolophine, Methadose);

• mirtazapine (Remeron);

• diet pills or cold medicines that contain dextromethorphan, ephedrine, pseudoephedrine, or phenylephrine;

• St. John"s wort;

• antidepressants such as amitriptyline (Elavil), amoxapine (Ascendin), bupropion (Wellbutrin, Zyban), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), protriptyline (Vivactil), sertraline (Zoloft), venlafaxine (Effexor), or trimipramine (Surmontil); or

• other MAO inhibitors such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or oral selegiline (Eldepryl).

After you stop using selegiline, you must wait at least 14 days before taking any of the medications listed above.

Tell your doctor if you are allergic to any drugs, or if you have:

• heart disease, high or low blood pressure;

• seizures or epilepsy; or

• a personal or family history of bipolar disorder (manic depression) or suicide attempt.

If you have any of these conditions, you may not be able to use selegiline, or you may need a dosage adjustment or special tests during treatment.

You may have suicidal thoughts or behavior when you first start using an antidepressant, especially if you are under 18 years old.

In addition to you watching for changes in your own symptoms, your family or caregivers should be alert to changes in your mood or symptoms.

How should I use selegiline transdermal?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use more of the skin patches or use them for longer than recommended. Follow the directions on your prescription label.

Foods that you MAY eat include:

• fresh meat, poultry, or fish (including lunch meat, hot dogs, breakfast sausage, and cooked sliced ham);

• any vegetables except broad bean pods (fava beans);

• processed cheese, mozzarella, ricotta, cottage cheese;

• pizza made with cheeses low in tyramine;

• soy milk, yogurt; or

• Brewer"s or baker"s yeast.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Before applying a skin patch, wash the skin with soap and water and dry completely. The patch can be worn on a dry, smooth, and hairless area of your back, upper arm, chest, or thigh. Do not apply the patch to a skin wound or irritated skin, or wear it under tight clothing.

Remove the patch after 24 hours, taking care not to touch the sticky side with your fingers. Fold the patch in half so that it sticks together. Throw the used patch away where children and pets cannot reach it.

Use only one patch at a time. While you are wearing the patch, do not expose it to sunlight or other sources of heat such as a heating pad, electric blanket, hot tub, or sauna.

What happens if I miss a dose?

Apply a skin patch as soon as you remember. If it is almost time to apply your next patch, skip the missed dose and apply a patch at your next regularly scheduled time. Do not use extra patches to make up the missed dose.

If a patch becomes loose, press it back in place. If a patch falls off, apply a new one and go back to your regular schedule for patch changes.

What happens if I overdose?

What should I avoid while using selegiline transdermal?

• air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring, and any spoiled or improperly stored beef, poultry, fish, or liver;

• beer from a tap, beer that has not been pasteurized;

• aged cheeses, including blue, boursault, brick, brie, camembert, cheddar, emmenthaler, gruyere, parmesan, romano, roquefort, stilton, and swiss;

• over-the-counter supplements or cough and cold medicines that contain tyramine;

• sauerkraut, soy beans, soy sauce, tofu, miso soup, bean curd, fava beans; or

• yeast extracts (such as Marmite).

Eating tyramine while you are using selegiline can raise your blood pressure to dangerous levels which could cause life-threatening side effects.

You should become very familiar with the list of foods to avoid while you are using selegiline.

Selegiline transdermal side effects

• sudden and severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, seizure (convulsions), and sudden numbness or weakness (especially on one side of the body);

• feeling light-headed, fainting;

• twitching muscle movements; or

• painful or difficult urination.

Continue using selegiline and talk with your doctor if you have any of these less serious side effects:

• constipation, gas, loss of appetite;

• swelling, numbness or tingling, easy bruising;

• muscle pain;

• dry mouth, sore throat, cough;

• redness or itching where the patch is worn; or

• impotence, loss of interest in sex, or trouble having an orgasm.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect selegiline transdermal?

Before using selegiline, tell your doctor if you have used any other type of antidepressant in the past 14 days, or if you are using buspirone (Buspar), or stimulants or amphetamines (such as ADHD medication).

There are many other medicines that can cause serious medical problems if you take them while using selegiline. Do not use selegiline before telling your doctor about all other prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Keep a list with you of all the medicines you use and show this list to any doctor, dentist, or other healthcare provider who treats you.

Where can I get more information?

• Your pharmacist has information about selegiline written for health professionals that you may read.

What does my medication look like?

Selegiline transdermal is available with a prescription under the brand name Emsam. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.