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TROSPIUM (Systemic)

Some commonly used brand names are:

In the U.S.—

  • Sanctura

Not commercially available in Canada.


  • Antispasmodic (urinary bladder)


Trospium (TROSE-pee-um) is used to treat bladder problems such as frequent need to urinate or loss of control of urinary function.

This medicine is available only with your doctor"s prescription, in the following dosage forms:

  • Oral
  • Tablets (U.S.)

Before Using This Medicine

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For trospium, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to trospium. Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—Trospium has not been studied in pregnant women. However, studies in animals have shown that trospium may cause unwanted effects in the fetus. Before taking this medicine, make sure your doctor knows if you are pregnant or if you become pregnant.

Breast-feeding—It is not known whether trospium passes into breast milk. However, trospium does pass into the milk of animals. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.

Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of trospium in children with use in other age groups.

Older adults—This medicine has been tested and has not been shown to cause different side effects or problems in older people than is does in younger adults. However, elderly patients are more likely to be sensitive to anticholinergic agents and may require a lower dose.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems—The presence of other medical problems may affect the use of trospium. Make sure you tell your doctor if you have any other medical problems, especially:

  • Glaucoma or
  • Stomach problems or
  • Urinary retention—Trospium may make these conditions worse.
  • Kidney problems or
  • Liver problems—A lower dose of trospium may be necessary.

Proper Use of This Medicine

Dosing—The dose of trospium will be different for different patients. Follow your doctor"s orders or the directions on the label . The following information includes only the average doses of trospium. If your dose is different, do not change it unless your doctor tells you to do so.

  • For oral dosage form (tablets):
    • To treat bladder problems:
      • Adults—20 milligrams (mg) one or two times a day 1 hour before meal.
      • Children—Use and dose must be determined by your doctor.

Missed dose—If you miss a dose of this medicine, take 1 hour before next meal. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage—To store this medicine:

  • Keep out of the reach of children.
  • Do not store in the bathroom, near the kitchen sink, or in other damp places. heat or moisture may cause the medicine to break down.
  • Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

This medicine may cause some people to have vision problems. Make sure your vision is clear before you drive or do anything else that could be dangerous if you are not able to see well.

This medicine, especially in high doses, may cause some people to become dizzy or drowsy. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

Avoid use of alcohol. Alcohol may increase your risk of drowsiness.

Use caution during exercise or hot weather. Overheating may result in heat stroke.

This medicine may cause dryness of the mouth, nose, and throat. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Frequency not determined—Observed during clinical practice

Blistering, peeling, loosening of skin; changes in vision; chills; clammy skin; confusion as to time, place, or person; cough; dark-colored urine; diarrhea; difficulty swallowing; dizziness; enlarged pupils; fast or slow heartbeat; fever; hallucinations; hives; holding false beliefs that cannot be changed by fact; increased sensitivity of eyes to light; increased sweating, possibly with fever or cold; itching; joint or muscle pain; muscle cramps or spasms; muscle pain or stiffness; puffiness or swelling of the eyelids or around the eyes, face, lips or tongue; red irritated eyes; red skin lesions, often with a purple center; seeing, hearing, or feeling things that are not there; severe chest pain; severe headache; shortness of breath; skin rash; sore throat; sores, ulcers, or white spots in mouth or on lips; stiff or sore neck; tightness in chest; unusual excitement, nervousness, or restlessness; unusual tiredness or weakness; wheezing

Symptoms of Overdose

Get emergency help immediately if any of the following symptoms of overdose occur

Bigger, dilated, or enlarged pupils [black part of eye]; blurred vision; confusion; constipation; delirium; difficult urination; dizziness; drowsiness; dry eyes, mouth, nose, or throat; eye pain; fast, pounding, or irregular heartbeat or pulse; flushing or redness of face; hallucinations; increased sensitivity of eyes to light; nausea; troubled breathing; vomiting

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.

More Common

Difficulty having a bowel movement (stool); dry mouth

Less common

Acid or sour stomach; belching; bloated full feeling; dry eyes; excess air or gas in stomach or intestines; headache; heartburn; indigestion; passing gas; stomach discomfort upset or pain; trouble in urinating; unable to have a bowel movement; upper stomach pain

Incidence unknown

Change in taste; dry skin; dry throat; loss of taste; swelling of abdominal or stomach area; vision blurred; vomiting

Frequency not determined—Observed during clinical practice

Burning feeling in chest or stomach; fainting; indigestion; tenderness in stomach area

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Developed: 09/02/2004

The information contained in the Thomson Healthcare (Micromedex) products as delivered by is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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Where can I get more information about Sanctura ? We recommend to use

Typical mistypes for Sanctura
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