Rifaximin

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Rifaximin


Generic Name: Rifaximin (riff-AX-ih-min)
Brand Name: Xifaxan

Rifaximin is used for:

Treating travelers" diarrhea caused by certain strains of bacteria in patients 12 years of age and older. It may be used for other conditions as determined by your doctor.

Rifaximin is an antibiotic. It works by slowing down the bacteria"s ability to reproduce, allowing the body to fight the infection more effectively.

Do NOT use Rifaximin if:

  • you are allergic to any ingredient in Rifaximin
  • you have diarrhea with a fever or blood in the stool

Contact your doctor or health care provider right away if any of these apply to you.

Before using Rifaximin :

Some medical conditions may interact with Rifaximin . Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines or other substances
  • if you have inflammation of the bowel (pseudomembranous colitis)
  • if you have a fever or blood in the stool

Some MEDICINES MAY INTERACT with Rifaximin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Delavirdine, gefitinib, and lamotrigine because their effectiveness may be decreased by Rifaximin

This may not be a complete list of all interactions that may occur. Ask your health care provider if Rifaximin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Rifaximin :

Use Rifaximin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Rifaximin comes with an additional patient leaflet. Read it carefully.
  • Rifaximin may be taken with or without food.
  • Rifaximin works best if it is taken at the same time each day.
  • To clear up your infection completely, continue taking Rifaximin for the full course of treatment even if you feel better in a few days.
  • If you miss a dose of Rifaximin , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Rifaximin .

Important safety information:

  • Contact your health care provider at once if diarrhea symptoms get worse or persist for more than 24 to 48 hours.
  • Dehydration from diarrhea may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous.
  • Long-term, repeated, or improper use of Rifaximin may cause a second infection. You may need to stop taking Rifaximin and start another medicine to treat the second infection. Contact your health care provider if signs of a second infection occur.
  • If severe diarrhea, stomach cramps/pain, or bloody stools occur, contact your health care provider at once. This could be a symptom of a serious side effect that needs immediate medical attention. Do not treat diarrhea without consulting your health care provider.
  • It is important use Rifaximin for the full course of treatment. Failure to do so may decrease the effectiveness of this treatment and may increase the risk that the bacteria will no longer be sensitive to Rifaximin and it will not be able to be treated by this or certain other antibacterial medicines in the future.
  • Rifaximin is not recommended for use in CHILDREN younger than 12 years of age; safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you are pregnant or planning to become pregnant, discuss you"re your doctor the benefits and risks of using Rifaximin during pregnancy. It is unknown if Rifaximin is excreted in breast milk. Do not breast-feed while taking Rifaximin .

Possible side effects of Rifaximin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; fever; gas; headache; nausea; sensations of needing to empty the bowel; stomach pain; urgent bowel movements; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; chest pain; fainting; severe diarrhea.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Rifaximin :

Store Rifaximin at room temperature between 68 and 77 degrees F (20 and 25 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Brief excursions at temperatures between 59 and 86 degrees F (15 and 30 degrees C) are permitted. Keep Rifaximin out of the reach of children and away from pets.

General information:

  • If you have any questions about Rifaximin , please talk with your doctor, pharmacist, or other health care provider.
  • Rifaximin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Rifaximin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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