Rifampin Capsules

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Rifampin Capsules


Generic Name: Rifampin Capsules (rif-am-pin)
Brand Name: Rifadin

Rifampin Capsules is used for:

The treatment of all forms of tuberculosis and the treatment of some people who have meningitis. It may also be used to treat other conditions as determined by your doctor.

Rifampin Capsules is an antituberculosis agent. It works by killing or stopping the growth of tuberculosis bacteria.

Do NOT use Rifampin Capsules if:

  • you are allergic to any ingredient in Rifampin Capsules
  • you have porphyria
  • you are taking HIV protease inhibitors (eg, ritonavir) or voriconazole

Contact your doctor or health care provider right away if any of these apply to you.

Before using Rifampin Capsules:

Some medical conditions may interact with Rifampin Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you are alcohol dependent or have alcohol withdrawal syndrome
  • if you have jaundice, cirrhosis, other liver disease, or inflammation or obstruction of the bile ducts

Some MEDICINES MAY INTERACT with Rifampin Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Many prescription and nonprescription medicines (eg, used for infections, blood thinners, high cholesterol, birth control, heart problems, HIV infection, mental or mood problems, seizures, diabetes) and herbs found in multivitamin products, herbal teas, and dietary supplements (eg, garlic, St. John"s wort) may interact with Rifampin Capsules and may increase the risk of side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Rifampin Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Rifampin Capsules:

Use Rifampin Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take this medication either 1 hour before or 2 hours after a meal with a full glass of water.
  • You should take this medication at least 1 hour before taking antacids.
  • To clear up your infection completely, continue using Rifampin Capsules for the full course of treatment even if you feel better in a few days
  • Rifampin Capsules works best if it is taken at the same time every day.
  • Separate doses by 8 to 12 hours if taking oral aminosalicylic acid.
  • Separate doses of rifampin and antacids. Take rifampin at least 1 hour before antacids.
  • If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your doctor. If more than one dose is missed, contact your doctor or pharmacist.

Ask your health care provider any questions you may have about how to use Rifampin Capsules.

Important safety information:

  • Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Rifampin Capsules.
  • Using Rifampin Capsules alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Rifampin Capsules may produce a reddish coloration of your urine, sweat, saliva, and tears. Rifampin Capsules may also permanently stain soft contact lenses.
  • Additional monitoring of your dose or condition might be necessary if you are taking isoniazid or itraconazole.
  • If you are using oral contraceptives for birth control, it is recommended that you use an additional form of birth control while taking Rifampin Capsules.
  • LAB TESTS, such as complete blood counts, may be needed to monitor your condition.
  • PREGNANCY and BREAST-FEEDING: If you are pregnant or planning on becoming pregnant, discuss with your doctor the benefits and risks of using Rifampin Capsules during pregnancy. Rifampin Capsules is excreted in breast milk. Do not breast-feed while taking Rifampin Capsules.

Possible side effects of Rifampin Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cramps; diarrhea; dizziness; drowsiness; gas; headache; heartburn; joint pain; loss of appetite; menstrual changes; nausea; stomach pain or bloating; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine; severe stomach pain; yellowing of eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include abdominal pain; headache; increasing lethargy; itching; nausea; vomiting. Unconsciousness may occur in severe liver disease. Liver enlargement and yellowing of eyes and skin may develop rapidly. Lowered blood pressure, heart abnormalities, and seizures may develop.

Proper storage of Rifampin Capsules:

Keep container tightly closed. Store in a dry place. Avoid excessive heat. Keep Rifampin Capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about Rifampin Capsules, please talk with your doctor, pharmacist, or other health care provider.
  • Rifampin Capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • If using Rifampin Capsules for an extended period of time, obtain refills before your supply runs out.

This information is a summary only. It does not contain all information about Rifampin Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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