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Altarussin CF, Ambenyl-D, Ambifed-G DM, Anatuss DM, Benylin Multi-Symptom Cough, Daytime Liquicap, Dimacol, Dorcol Childrens Cough, Guaifenex DM RX, Multi Symptom Cough and Cold, Novahistine DMX, PanMist-DM, Profen Forte DM, Profen II DM, Profen II DM Liquid, Protuss DM, Relacon-DM NR, Rhinosyn-X, Robitussin CF, Robitussin Cold and Cough, Robitussin Pediatric Cough and Decongestant, Ru-Tuss Expectorant, S-Pak DM, Suda-Tussin DM, Sudafed Cough, Sudafed Cough Syrup, Syn-Rx DM, Touro CC, Touro CC-LD, Tussafed-LA, Tussin Cough and Cold, |Rhinosyn-X

Rhinosyn-X

Generic Name: dextromethorphan, guaifenesin, and pseudoephedrine (dex troe meth OR fan, gwye FEN e sin, soo doe e FED rin)
Brand Names: Altarussin CF, Ambenyl-D, Ambifed-G DM, Anatuss DM, Benylin Multi-Symptom Cough, Daytime Liquicap, Dimacol, Dorcol Childrens Cough, Guaifenex DM RX, Multi Symptom Cough and Cold, Novahistine DMX, PanMist-DM, Profen Forte DM, Profen II DM, Profen II DM Liquid, Protuss DM, Relacon-DM NR, Rhinosyn-X, Robitussin CF, Robitussin Cold and Cough, Robitussin Pediatric Cough and Decongestant, Ru-Tuss Expectorant, S-Pak DM, Suda-Tussin DM, Sudafed Cough, Sudafed Cough Syrup, Syn-Rx DM, Touro CC, Touro CC-LD, Tussafed-LA, Tussin Cough and Cold

What is dextromethorphan, guaifenesin, and pseudoephedrine?

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of dextromethorphan, guaifenesin, and pseudoephedrine is used to treat stuffy nose, sinus congestion, cough, and chest congestion caused by the common cold or flu.

Dextromethorphan, guaifenesin, and pseudoephedrine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about dextromethorphan, guaifenesin, and pseudoephedrine?

What should I discuss with my healthcare provider before using dextromethorphan, guaifenesin, and pseudoephedrine?

Before taking this medicine, tell your doctor if you are allergic to any drugs or if you have emphysema or chronic bronchitis. You may not be able to use this medication, or you may need a dosage adjustment or special tests during treatment.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take dextromethorphan, guaifenesin, and pseudoephedrine?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Symptoms of an overdose may include feeling restless or nervous.

What should I avoid while taking dextromethorphan, guaifenesin, and pseudoephedrine?

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor"s advice. Taking a stimulant together with cough or cold medicine can increase your risk of unpleasant side effects.

What are the possible side effects of dextromethorphan, guaifenesin, and pseudoephedrine?

• severe dizziness, anxiety, restless feeling, or nervousness;

• confusion, hallucinations; or

• slow, shallow breathing.

Keep using the medication and talk with your doctor if you have any of these less serious side effects:

• dizziness or headache,

• a rash, or

• nausea, vomiting, or stomach upset.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect dextromethorphan, guaifenesin, and pseudoephedrine?

Before taking dextromethorphan, guaifenesin, and pseudoephedrine, tell your doctor if you are using any of the following drugs:

• celecoxib (Celebrex);

• cinacalcet (Sensipar);

• darifenacin (Enablex);

• imatinib (Gleevec);

• quinidine (Quinaglute, Quinidex);

• ranolazine (Ranexa)

• ritonavir (Norvir);

• sibutramine (Meridia);

• terbinafine (Lamisil);

• medicines to treat high blood pressure; or

• antidepressant medications such as amitriptyline (Elavil, Etrafon), bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), paroxetine (Paxil), sertraline (Zoloft), and others.

If you are using any of these drugs, you may not be able to use dextromethorphan, guaifenesin, and pseudoephedrine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect dextromethorphan, guaifenesin, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist has information about dextromethorphan, guaifenesin, and pseudoephedrine written for health professionals that you may read.

What does my medication look like?

Dextromethorphan, guaifenesin, and pseudoephedrine is available with a prescription under many different brand and generic names. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.