Requip

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Requip, |Requip

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Requip

Generic Name: ropinirole (oral) (ro PIN ih rol)
Brand Names: Requip

What is ropinirole?

Ropinirole has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson"s disease.

Ropinirole is used to treat symptoms of Parkinson"s disease, such as stiffness, tremors, muscle spasms, and poor muscle control. Ropinirole is also used to treat restless legs syndrome (RLS).

Ropinirole may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about ropinirole?

Some people taking ropinirole have fallen asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness. If you are unsure of how this medicine will affect you, be careful if you drive or do anything that requires you to be awake and alert.

Dizziness or drowsiness may be more likely to occur when you rise from a sitting or lying position. Rise slowly and use caution to prevent a fall.

Avoid using other medicines that make you sleepy (such as alcohol, cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by ropinirole.

Avoid drinking alcohol, which can increase some of the side effects of ropinirole.

Ropinirole may cause hallucinations (the sensation of hearing or seeing something that is not there), most commonly among elderly people. Call your doctor if you experience hallucinations.

Do not stop using ropinirole or change your dose without first talking to your doctor. You may have side effects such as fever, muscle stiffness, and confusion if you stop the medication suddenly or if you change doses.

What should I discuss with my healthcare provider before taking ropinirole?

Some people taking ropinirole have fallen asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness. If you are unsure of how this medicine will affect you, be careful if you drive or do anything that requires you to be awake and alert.

Before taking this medication, tell your doctor if you have heart disease, kidney disease, or liver disease. If you have any of these conditions, you may not be able to use ropinirole, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether ropinirole passes into breast milk or if it could harm a nursing baby. Ropinirole may reduce breast milk production. Do not take ropinirole without telling your doctor if you are breast-feeding a baby. Ropinirole may cause hallucinations (the sensation of hearing or seeing something that is not there), most commonly among elderly people. Call your doctor if you experience hallucinations.

How should I take ropinirole?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. The dose and timing of ropinirole in treating Parkinson"s diease is different from the dose and timing in treating RLS.

You may receive ropinirole in a starting kit that has each pill marked with the day you should take it. Do not mix these pills up because they each contain different amounts of ropinirole. The pills must be taken in order so that you gradually receive higher doses of the medication.

You may have a brief increase in side effects whenever your dose is changed.

Ropinirole can be taken with or without food. Nausea is a common side effect of ropinirole. Taking the medicine with food may lessen this effect.

It may be several weeks or months before you notice that this medicine working. Continue taking the medicine until your doctor recommends that you stop.

Do not stop using ropinirole or change your dose without first talking to your doctor. You may have side effects such as fever, muscle stiffness, and confusion if you stop the medication suddenly or if you change doses. Store ropinirole at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a ropinirole overdose may include nausea, vomiting, weakness, fainting, agitation, confusion, hallucinations, muscle twitching, tingly feeling, and chest pain.

What should I avoid while taking ropinirole?

Ropinirole can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid smoking, which can make ropinirole less effective.

Avoid using other medicines that make you sleepy (such as alcohol, cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by ropinirole.

Avoid drinking alcohol, which can increase some of the side effects of ropinirole.

Dizziness or drowsiness may be more likely to occur when you rise from a sitting or lying position. Rise slowly and use caution to prevent a fall.

Ropinirole side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
  • fever, muscle stiffness, feeling light-headed; or

  • slow heartbeat, fainting.

Call your doctor promptly if you fall asleep during a daily activity, if you faint, or if you have hallucinations (hearing or seeing something that is not there). Your doctor may want you to stop taking ropinirole, or take a lower dose.

Other, less serious side effects may be more likely to occur, such as:

  • mild nausea, vomiting, upset stomach, or loss of appetite;

  • worsened RLS symptoms early in the morning;

  • diarrhea or constipation;

  • dry mouth, sweating;

  • headache;

  • drowsiness or confusion;

  • sleep problems (insomnia); or

  • agitation or anxiety.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Some people using ropinirole have developed a gambling habit. It is not known whether ropinirole actually causes this effect. Talk with your doctor if you believe you have an unusual urge to gamble while you are taking ropinirole.

What other drugs will affect ropinirole?

Before taking ropinirole, tell your doctor if you are using any of the following drugs:

  • levodopa;

  • ciprofloxacin (Cipro);

  • a medication used to treat nausea and vomiting or mental illness, such as chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), thioridazine (Mellaril), promazine (Sparine), trifluoperazine (Stelazine), thiothixene (Navane), or haloperidol (Haldol); or
  • an estrogen such as Premarin, Prempro, Estratest, Ogen, Estraderm, Climara, Vivelle, estradiol, and others.

If you are using any of these drugs, you may not be able to use ropinirole, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect ropinirole. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist has more information about ropinirole written for health professionals that you may read.

What does my medication look like?

Ropinirole is available with a prescription under the brand name Requip. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Requip 0.25 mg--white tablets with beveled edges

  • Requip 0.5 mg--yellow tablets with beveled edges

  • Requip 1.0 mg--pale-green tablets with beveled edges

  • Requip 2.0 mg--pale, yellowish-pink tablets with beveled edges

  • Requip 5.0 mg--pale-blue tablets with beveled edges

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 6.01. Revision Date: 5/9/06 3:50:16 PM.



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