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Generic Name: Metoclopramide Tablets (meht-oh-KLOE-pra-mide)
Brand Name: Reglan
Reglan is used for:
Treating symptoms of gastroesophageal reflux disease (GERD) (heartburn)
in patients who do not respond to other treatment. It is also used to treat symptoms associated with a certain digestive problem in diabetic patients
(diabetic gastroparesis). It may also be used for other conditions as determined by your doctor.
Reglan is a gastrointestinal stimulant and anti-nauseant. It works by increasing the movement of the stomach and intestines to help move food and acid out of the stomach more quickly. It also works in certain areas in the brain to decrease nausea.
Do NOT use Reglan if:
- you are allergic to any ingredient in Reglan
- you have seizures (eg, epilepsy); bleeding, blockage, or perforation in your stomach or intestines; or tumors
on your adrenal gland (pheochromocytoma)
- you are taking cabergoline or pergolide
- you are taking medicines, such as phenothiazines (eg, chlorpromazine), that may cause extrapyramidal reactions (abnormal, involuntary muscle movements of the head, neck, or limbs)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Reglan :
Some medical conditions may interact with Reglan . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have depression, asthma, heart failure, high blood pressure, diabetes,
Parkinson disease, blood problems (eg, porphyria), kidney problems, or low levels of an enzyme called methemoglobin reductase
Some MEDICINES MAY INTERACT with Reglan . Tell your health care provider if you are taking any other medicines, especially any of the following:
- Cisapride or droperidol because side effects, such as muscle rigidity, increased heart rate, and altered mental abilities, may occur
- Anticholinergic medicine (eg, hyoscyamine), certain antihistamines (eg, diphenhydramine), or narcotic pain medicines (eg, codeine) because they may decrease Reglan "s effectiveness
- Acetaminophen, alcohol, levodopa, phenothiazines (eg, chlorpromazine), sedatives (eg, zolpidem), selective serotonin reuptake inhibitors (SSRIs)
(eg, fluoxetine), succinylcholine, or tetracycline because the risk of their side effects may be increased
- Monoamine oxidase inhibitors (eg, phenelzine) because the risk of serious side effects (eg, high blood pressure, seizures) may be increased
- Cabergoline, digoxin, or pergolide because their effectiveness may be decreased by Reglan
This may not be a complete list of all interactions that may occur. Ask your health care provider if Reglan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Reglan :
Use Reglan as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Reglan by mouth 30 minutes before meals unless directed otherwise by your doctor.
- It may take several days to weeks for Reglan to work. Do not stop taking Reglan without checking with
- If you miss a dose of Reglan , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Reglan .
Important safety information:
- Reglan may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Reglan with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Reglan without first checking with your doctor; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Diabetes patients - Reglan may affect your
blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Reglan . Symptoms may include fever; stiff muscles;
confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.
- Lab tests, including liver and kidney function tests, may be performed while you use Reglan . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Reglan should not be used in CHILDREN younger than 15 years old;
safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Reglan while you are pregnant. This
medicine is found in breast milk. If you are or will be breast-feeding while you use Reglan , check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Reglan :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Agitation; anxiety; breast growth; changes in menstrual flow; confusion; diarrhea; dizziness; drowsiness;
foot tapping; frequent urination; headache; inability to sit still; jitteriness;
lack of energy; loss of bladder control; nausea; pacing; restlessness; sleeplessness; spontaneous flow of breast milk; tiredness.
Severe allergic reactions (rash; hives; itching; difficulty breathing;
tightness in the chest; swelling of the mouth, face, lips, or tongue); altered mental abilities, including lack of response to
surroundings; breathing problems;
depression with thoughts of suicide; fever; fluid retention; hallucinations;
hives; impotence; increased body heat;
increased heart rate; involuntary movements of tongue, face, mouth or jaw
(eg, sticking out of the tongue, puffing of cheeks, puckering of mouth, chewing movements), sometimes with involuntary movements of the arms and legs; irregular heart rhythm; irregular pulse and blood pressure; mood changes; muscle rigidness;
muscle twitching; rash; seizures; slow movements with tremor; sweating; swelling in the throat area; tightness in the lungs; unusual or unexplained vision changes; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088
(1-800-332-1088) or at
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include agitation; confusion;
drowsiness; muscle restlessness; unusual movement of eyes, face, or limbs.
Proper storage of Reglan :
Store Reglan at room temperature, between 68 and 77 degrees F
(20 and 25 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Reglan out of the reach of children and away from pets.
- If you have any questions about Reglan , please talk with your doctor, pharmacist, or other health care provider.
- Reglan is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Reglan . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.
Where can I get more information about Reglan ? We recommend to use www.Drugs.com
Typical mistypes for Reglan
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