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|Quinine

Quinine

Quinine is used for:

Treating malaria. It is usually used with other anti-malarial medicines. It may also be used for other conditions as determined by your doctor.

Quinine is an antimalarial. It works by killing the malaria parasite.

Do NOT use Quinine if:

• you are allergic to any ingredient in Quinine
• you have a history of a low platelet count (thrombocytopenia) or bleeding problems caused by using Quinine in the past
• you have glucose-6-phosphate dehydrogenase (G-6-PD) deficiency, ringing in the ears, inflammation of the optic (eye) nerve, or a history of certain blood problems (eg, blackwater fever, intravascular hemolysis)
• you are taking cisapride, dofetilide, terfenadine, or astemizole

Contact your doctor or health care provider right away if any of these apply to you.

Before using Quinine :

Some medical conditions may interact with Quinine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart problems (eg, irregular heartbeat), depression, low blood sugar, myasthenia gravis, seizures, or a family history of G-6-PD deficiency
• if you have vision problems, eye pain, or a bleeding disorder (eg, thrombocytopenic pupura)
• you are scheduled for surgery or anesthesia

Some MEDICINES MAY INTERACT with Quinine . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Acetazolamide, arsenic, astemizole, ketolide antibiotics (eg, telithromycin), macrolide antibiotics (eg, erythromycin), sodium bicarbonate, or terfenadine because the side effects of Quinine , including irregular heartbeat, may be increased
• Anticoagulants (eg, warfarin), cisapride, digoxin, or dofetilide because the risk of side effects, such as bleeding and irregular heartbeat, may be increased
• Rifampin because the effectiveness of Quinine may be decreased
• Anticholinesterase medicines (eg, neostigmine) because the effectiveness may be decreased by Quinine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Quinine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Quinine :

Use Quinine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Quinine may be taken with food if it upsets your stomach.
• Do not take aluminum-containing antacids within 1 hour before or 2 hours after taking Quinine .
• Avoid eating grapefruit or drinking grapefruit juice while taking Quinine .
• Continue taking Quinine for the full course of treatment even if you feel better in a few days.
• Do not miss any doses. If you miss a dose of Quinine , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Quinine .

Important safety information:

• Quinine may cause dizziness, lightheadedness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Quinine . Using Quinine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• If your symptoms do not improve within a few days or if they become worse, check with your doctor.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Quinine .
• PREGNANCY and BREAST-FEEDING: Do not use Quinine if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. Quinine is excreted in breast milk. If you are or will be breast-feeding while you are using Quinine , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Quinine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; nausea; nervousness; restlessness; stomach cramps; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision, double vision, light sensitivity, or other unusual vision changes; chest pain; confusion; dark urine; decreased amount of urine or trouble urinating; decreased hearing, hearing loss, or ringing in the ears; fainting; fast heartbeat; fatigue; fever, chills, or sore throat; flushing; loss of appetite; mood or mental problems; personality changes; severe dizziness or lightheadedness; severe stomach pain; sudden onset of cold sweat; unusual bleeding or bruising; unusual tiredness or weakness; weight loss; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include confusion; dilated pupils; loss of consciousness; nausea and vomiting; rash; ringing in the ears; seizures; severe dizziness; slow or irregular heartbeat; stomach cramping or pain; urine discoloration; vision loss.

Store Quinine between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Quinine out of the reach of children and away from pets.

General information:

• If you have any questions about Quinine , please talk with your doctor, pharmacist, or other health care provider.
• Quinine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Quinine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.