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|Protopam Chloride |
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In Canada—
Generic name product may be available in the U.S. Other commonly used names are 2-PAM and 2-PAM chloride . Category
DescriptionPralidoxime (pra-li-DOX-eem) is used together with another medicine called atropine to treat poisoning caused by organic phosphorus pesticides (e.g., diazinon, malathion, mevinphos, parathion, and sarin) and by organophosphate chemicals (“nerve gases”) used in chemical warfare. Pralidoxime is also used to treat overdose of medicines, such as ambenonium, neostigmine, and pyridostigmine, that are used to treat myasthenia gravis. Poisoning with these chemicals or medicines causes your muscles, including the muscles that help you breathe, to become weak. Pralidoxime is used to help you get back strength in your muscles. Pralidoxime is to be given only by or under the direct supervision of a doctor or trained military personnel. It is available in the following dosage form:
Before Using This MedicineIn deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For pralidoxime, the following should be considered: Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to pralidoxime. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes. Pregnancy—Studies on effects in pregnancy have not been done in either humans or animals. Breast-feeding—It is not known whether pralidoxime passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor. Children—Although there is no specific information comparing use of pralidoxime in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults. Older adults—Many medicines have not been studied specifically in older people. Therefore it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no information comparing use of pralidoxime in the elderly with use in other age groups. Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are using pralidoxime, it is especially important that your health care professional know if you are taking any of the following:
Other medical problems—The presence of other medical problems may affect the use of pralidoxime. Make sure you tell your doctor if you have any other medical problems, especially:
Proper Use of This MedicineFor patients using the pralidoxime auto-injector (automatic injection device):
Use this medicine only as directed. Do not use more of it and do not use it more often than your doctor or medic ordered . Do not use more than recommended on the label unless otherwise directed by your doctor or medic. Dosing—The dose of pralidoxime will be different for different patients. Follow your doctor"s or medic"s orders or the directions on the label . The following information includes only the average doses of pralidoxime.
Storage—To store this medicine:
Precautions While Using This MedicineThis medicine will add to the effects of CNS depressants (medicines that may make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine. Side Effects of This MedicineAlong with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor as soon as possible if any of the following side effects occur: More common Blurred or double vision; difficulty in focusing your eyes; difficulty in speaking; difficult or rapid breathing; dizziness; fast heartbeat; muscle stiffness or weakness; pain at the place of injection (after injection into a muscle) Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome: More common Drowsiness; headache; nausea Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor. Additional InformationOnce a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, pralidoxime has been used in some patients to treat poisoning caused by certain carbamate pesticides. Other than the above information, there is no additional information relating to proper use, precautions, or side effects for this use. Revised: 04/01/1996 The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products. Where can I get more information about Protopam Chloride ? 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