Primatene Mist Aerosol

|Primatene Mist Aerosol

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Primatene Mist Aerosol

Generic Name: Epinephrine Inhalation Aerosol (ep-i-NEF-rin)
Brand Name: Examples include Asthmahaler and Primatene Mist

Primatene Mist Aerosol is used for:

Treating shortness of breath, chest tightness, and wheezing associated with asthma, emphysema, and other breathing problems. It may also be used for other conditions as determined by your doctor.

Primatene Mist Aerosol is an alpha- and beta-receptor stimulant. It works by widening the airway, which makes it easier to breathe.

Do NOT use Primatene Mist Aerosol if:

  • you are allergic to any ingredient in Primatene Mist Aerosol
  • you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Primatene Mist Aerosol:

Some medical conditions may interact with Primatene Mist Aerosol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have an overactive thyroid, urinary problems, an enlarged prostate, diabetes, high blood pressure, ischemic heart disease, irregular heartbeat, or other heart problems

Some MEDICINES MAY INTERACT with Primatene Mist Aerosol. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), droxidopa, or phenothiazines (eg, chlorpromazine) because the risk of high or low blood pressure and fast or slow heartbeat may be increased
  • Bromocriptine, furazolidone, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects, such as headache, high temperature, and high blood pressure, may be increased
  • Catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), digoxin, or medicines for irregular heartbeat (eg, quinidine) because the effects of Primatene Mist Aerosol may be increased
  • Guanethidine because its effectiveness may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Primatene Mist Aerosol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Primatene Mist Aerosol:

Use Primatene Mist Aerosol as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.

  • Primatene Mist Aerosol comes with an additional patient leaflet. Read it carefully and reread it each time you get Primatene Mist Aerosol refilled. Ask your doctor or pharmacist any questions that you may have about Primatene Mist Aerosol.
  • Before using Primatene Mist Aerosol, be sure that the canister is properly inserted into the inhaler unit and shake well. Exhale slowly and completely. Unless your doctor has told you otherwise, position the mouthpiece between your lips and try to rest your tongue flat. Your doctor may have told you to hold the inhaler 1 or 2 inches (2 or 3 centimeters) away from the open mouth or may have instructed you to use a special spacing device. As you start to take a slow deep breath, press the canister and mouthpiece together at exactly the same time to administer a dose of Primatene Mist Aerosol. Continue inhaling slowly and deeply and hold for as long as comfortable, then exhale slowly through pursed lips or through nose. If more than 1 inhalation is to be used, wait a few minutes and repeat the above process. Keep the spray away from your eyes.
  • If you miss a dose of Primatene Mist Aerosol, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Primatene Mist Aerosol.

Important safety information:

  • Do not increase your dose or use Primatene Mist Aerosol more often than prescribed without checking with your doctor.
  • If your symptoms do not improve or if they worsen, check with your doctor.
  • Primatene Mist Aerosol may cause dry mouth or an unpleasant taste in your mouth. Rinsing your mouth with water after each dose may help relieve these effects.
  • Primatene Mist Aerosol is not recommended for use in CHILDREN younger than 4 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while using Primatene Mist Aerosol, discuss with your doctor the benefits and risks of using Primatene Mist Aerosol during pregnancy. Primatene Mist Aerosol is excreted in breast milk. If you are or will be breast-feeding while you are using Primatene Mist Aerosol, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Primatene Mist Aerosol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Difficulty sleeping; fast heartbeat; headache; loss of appetite; nausea; nervousness; tremors.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); wheezing.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include headache; irregular heartbeat; nausea; tremor; vomiting; weakness.

Proper storage of Primatene Mist Aerosol:

Store Primatene Mist Aerosol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not puncture, break, or burn the canister even if it appears to be empty. Keep Primatene Mist Aerosol out of the reach of children and away from pets.

General information:

  • If you have any questions about Primatene Mist Aerosol, please talk with your doctor, pharmacist, or other health care provider.
  • Primatene Mist Aerosol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Primatene Mist Aerosol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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