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Prevpac, |Prevpac

Prevpac

Generic Name: amoxicillin, clarithromycin, and lansoprazole (a mox i SILL in, kla rith roe MYE sin, and lan SAW pra zol)
Brand Names: Prevpac

What are amoxicillin, clarithromycin, and lansoprazole?

Amoxicillin is an antibiotic in the class of drugs called penicillins. It fights bacteria in your body.

Clarithromycin is an antibiotic in a class of drugs called macrolides. Clarithromycin also fights bacteria in your body.

Lansoprazole decreases the amount of acid produced in your stomach.

The combination, amoxicillin, clarithromycin, and lansoprazole, is used to decrease the amount of acid in the stomach and to treat Helicobacter pylori, a bacterial infection involved in causing stomach ulcers.

Amoxicillin, clarithromycin, and lansoprazole may also be used for conditions other than those listed in this medication guide.

What is the most important information I should know about amoxicillin, clarithromycin, and lansoprazole?

What should I discuss with my healthcare provider before taking amoxicillin, clarithromycin, and lansoprazole?

• terfenadine (Seldane, Seldane-D),

• cisapride (Propulsid), or

• pimozide (Orap).

The medicines listed above may interact with clarithromycin, possibly resulting in a dangerous irregular heartbeat pattern.

Before taking this medication, tell your doctor if you have

• kidney disease,

• liver disease, or

• an allergy to penicillins or cephalosporins.

You may not be able to take amoxicillin, clarithromycin, and lansoprazole, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

How should I take amoxicillin, clarithromycin, and lansoprazole?

Take amoxicillin, clarithromycin, and lansoprazole exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Each four-pill dose consists of one pink-and-black lansoprazole (Prevacid) capsule, two maroon-and-pink amoxicillin (Trimox) capsules, and one yellow clarithromycin (Biaxin) tablet.

Amoxicillin, clarithromycin, and lansoprazole is usually taken twice a day (every 12 hours), before eating. Follow your doctor"s instructions.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Symptoms of an amoxicillin, clarithromycin, and lansoprazole overdose are not known but might include nausea, vomiting, diarrhea, abdominal discomfort, muscle spasms or weakness, pain or twitching, pain in the fingers or toes, loss of feeling in the fingers or toes, seizures, confusion, coma, and agitation.

What should I avoid while taking amoxicillin, clarithromycin, and lansoprazole?

There are no restrictions on food, beverages, or activity while you are taking amoxicillin, clarithromycin, and lansoprazole, unless your doctor directs otherwise.

What are the possible side effects of amoxicillin, clarithromycin, and lansoprazole?

Other, less serious side effects may be more likely to occur. Continue to take amoxicillin, clarithromycin, and lansoprazole and talk to your doctor if you experience

• changes in taste,

• headache,

• diarrhea or nausea,

• dark stools,

• dark tongue,

• dry mouth or increased thirst, or

• a yeast infection.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect amoxicillin, clarithromycin, and lansoprazole?

• terfenadine (Seldane, Seldane-D),

• cisapride (Propulsid), or

• pimozide (Orap).

The medicines listed above may interact with clarithromycin, possibly resulting in a dangerous irregular heartbeat pattern.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

• digoxin (Lanoxin, Lanoxicaps);

• theophylline (Theo-Dur, Theolair, Theochron, others);

• sucralfate (Carafate);

• triazolam (Halcion);

• astemizole (Hismanal);

• warfarin (Coumadin);

• ergotamine (Cafergot, Ercaf, Ergostat, Ergomar, others) or dihydroergotamine (D.H.E. 45);

• carbamazepine (Tegretol), phenytoin (Dilantin), or valproate (Depakote, Depakene);

• cyclosporine (Neoral, Sandimmune);

• tacrolimus (Prograf);

• lovastatin (Mevacor) or simvastatin (Zocor);

• disopyramide (Norpace);

• allopurinol (Zyloprim);

• probenecid (Benemid); or

• methotrexate (Rheumatrex).

You may not be able to take amoxicillin, clarithromycin, and lansoprazole, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with amoxicillin, clarithromycin, and lansoprazole. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

• Your pharmacist has additional information about amoxicillin, clarithromycin, and lansoprazole written for health professionals that you may read.

What does my medication look like?

Amoxicillin, clarithromycin, and lansoprazole is available with a prescription under the brand name Prevpac. Other brand and generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you. Prevpac contains 3 separate medications in 14 daily packets as follows:

• Prevacid 30 mg-pink and black capsules

• Trimox 500 mg--maroon and light-pink capsules

• Biaxin 500 mg-yellow, oval, film-coated tablets

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.