Prevacid NapraPac Delayed-Release Capsules

|Prevacid NapraPac Delayed-Release Capsules

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Prevacid NapraPac Delayed-Release Capsules

Generic Name: Lansoprazole Delayed-Release Capsules and Naproxen Tablets (lan-SOE-pra-zole/na-PROX-en)
Brand Name: Prevacid NapraPac

Prevacid NapraPac Delayed-Release Capsules is used for:

Treating the signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis in patients who have had a stomach ulcer condition in the past.

Prevacid NapraPac Delayed-Release Capsules is a combination nonsteroidal anti-inflammatory drug (NSAID) and proton pump inhibitor. It works by treating inflammation and reducing the amount of acid the stomach produces. It may also reduce the risk of new ulcers associated with naproxen use.

Do NOT use Prevacid NapraPac Delayed-Release Capsules if:

  • you are allergic to any ingredient in Prevacid NapraPac Delayed-Release Capsules
  • you have experienced asthma, hives, runny nose, nasal polyps, or an allergic reaction after taking similar medicines or aspirin
  • you are taking aspirin, another NSAID (eg, ibuprofen), another proton pump inhibitor (eg, omeprazole), another form of naproxen, an aminoglycoside (eg, gentamicin), an HIV protease inhibitor (eg, indinavir), or heparin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Prevacid NapraPac Delayed-Release Capsules:

Some medical conditions may interact with Prevacid NapraPac Delayed-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney or liver problems or heart problems
  • if you regularly consume large amounts of alcohol or if you smoke

Some MEDICINES MAY INTERACT with Prevacid NapraPac Delayed-Release Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), aminoglycosides (eg, gentamicin), cyclosporine, macrolide immunosuppressants (eg, tacrolimus), or triamterene because toxicity to the kidney cells or kidney failure may occur
  • Probenecid or voriconazole because the actions and side effects of Prevacid NapraPac Delayed-Release Capsules may be increased
  • Anticoagulants (eg, warfarin), heparin, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because side effects, including risk of bleeding, may be increased by Prevacid NapraPac Delayed-Release Capsules
  • Lithium, methotrexate, or quinolones (eg, ciprofloxacin) because the effects of these medicines may be increased
  • Aspirin, beta-blockers (eg, atenolol), HIV protease inhibitors (eg, indinavir), imidazole antifungals (eg, ketoconazole), loop diuretics (eg, furosemide), other NSAIDs (eg, ibuprofen), other proton pump inhibitors (eg, omeprazole), or thiazide diuretics (eg, hydrochlorothiazide) because the effectiveness of these medicines may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Prevacid NapraPac Delayed-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Prevacid NapraPac Delayed-Release Capsules:

Use Prevacid NapraPac Delayed-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Prevacid NapraPac Delayed-Release Capsules comes with an additional patient information sheet called a Medication Guide. Read it carefully and reread it each time you get Prevacid NapraPac Delayed-Release Capsules refilled.
  • If you take sucralfate, do not take it within 30 minutes of taking Prevacid NapraPac Delayed-Release Capsules.
  • Swallow lansoprazole capsules whole. Do not break, crush, or chew before swallowing.
  • Lansoprazole is taken once a day and naproxen is taken twice a day. Unless otherwise directed by your doctor, you should take the lansoprazole capsule and a naproxen tablet in the morning with a full glass of water before eating. You should take the second dose of naproxen in the evening with a full glass of water.
  • If you miss a dose of Prevacid NapraPac Delayed-Release Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Prevacid NapraPac Delayed-Release Capsules.

Important safety information:

  • Prevacid NapraPac Delayed-Release Capsules may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Prevacid NapraPac Delayed-Release Capsules. Using Prevacid NapraPac Delayed-Release Capsules alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Prevacid NapraPac Delayed-Release Capsules contains naproxen. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains naproxen. If it does or if you are uncertain, contact your doctor or pharmacist.
  • Naproxen is an NSAID. NSAIDs have been associated with serious, possibly fatal, heart and blood vessel risks such as heart attack and stroke. This risk increases with long-term use of NSAIDs or if you have heart problems. NSAIDs should not be used right before or after bypass heart surgery. Additionally, NSAIDs can cause serious, possibly fatal stomach ulcers and bleeding, which can occur without warning signs. The following factors increase the risk of serious stomach problems in patients being treated with NSAIDs: history of stomach bleeding or ulcer disease, long-term use of NSAIDs, smoking, use of alcohol, poor health, older age, use of certain medicines such as anticoagulants (eg, warfarin) or corticosteroids (eg, prednisone) while taking an NSAID. To reduce your risk of serious side effects, take Prevacid NapraPac Delayed-Release Capsules exactly as instructed, at the lowest dose possible, and for the shortest time needed.
  • Use Prevacid NapraPac Delayed-Release Capsules regularly in order to get the most benefit from it. To help you remember, use it at the same time(s) each day. Do not miss any doses.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Prevacid NapraPac Delayed-Release Capsules.
  • This medicine may alter certain lab test results. Make sure laboratory personnel and your doctors know that you use Prevacid NapraPac Delayed-Release Capsules.
  • LAB TESTS, such as blood clotting tests, may be performed to monitor your progress or to check for side effects. These tests are more likely to be necessary if you are taking Prevacid NapraPac Delayed-Release Capsules for a long period of time. Be sure to keep all doctor and lab appointments.
  • Use Prevacid NapraPac Delayed-Release Capsules with caution in the ELDERLY, especially at higher doses, because they may be more sensitive to its effects.
  • Prevacid NapraPac Delayed-Release Capsules is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: When Prevacid NapraPac Delayed-Release Capsules is used after the third month of pregnancy, it can cause injury or even death to the developing fetus. Stop taking Prevacid NapraPac Delayed-Release Capsules as soon as possible if you become pregnant. Naproxen is excreted in breast milk. It is unknown if lansoprazole is excreted in breast milk. Do not breast-feed while taking Prevacid NapraPac Delayed-Release Capsules.

Possible side effects of Prevacid NapraPac Delayed-Release Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; depression; diarrhea; dizziness; drowsiness; headache; heartburn; indigestion; lightheadedness; mouth irritation; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black stools; bleeding; bloating; change in the amount of urine; dark urine; easy bruising or bleeding; hearing changes; mental or mood changes; persistent sore throat or fever; persistent stomach or abdominal pain; pounding in the chest; ringing in the ears; severe headache; stomach pain; sudden or unexplained weight gain; swelling of the hands, legs, or feet; ulcers; unusual tiredness; very stiff neck; vision changes; vomit that looks like coffee grounds; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include extreme drowsiness; loss of consciousness; seizures; severe stomach pain; vomiting or vomit that looks like coffee grounds.

Proper storage of Prevacid NapraPac Delayed-Release Capsules:

Store Prevacid NapraPac Delayed-Release Capsules at 77 degrees F (25 degrees C) in the original container. Store away from heat, light, and moisture. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Keep Prevacid NapraPac Delayed-Release Capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about Prevacid NapraPac Delayed-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.
  • Prevacid NapraPac Delayed-Release Capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Prevacid NapraPac Delayed-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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