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Some commonly used brand names are:
In the U.S.—
Lansoprazole (lan-SOE-pra-zole) is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat duodenal and gastric ulcers and gastroesophageal reflux disease (GERD), a condition in which the acid in the stomach washes back up into the esophagus. Sometimes lansoprazole is used in combination with antibiotics to treat ulcers associated with infection caused by the H. pylori bacteria (germ).
Lansoprazole is also used to treat Zollinger-Ellison disease, a condition in which the stomach produces too much acid.
Lansoprazole works by decreasing the amount of acid produced by the stomach.
This medicine is available only with your doctor"s prescription.
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For lansoprazole, the following should be considered:
Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to lansoprazole. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy—Studies have not been done in humans. However, studies in animals have not shown that lansoprazole causes harm to the fetus.
Breast-feeding—Lansoprazole may pass into the breast milk. Since this medicine has been shown to cause unwanted effects such as tumors in animals, it may be necessary for you to take another medicine or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor.
Children—There is no specific information comparing the use of oral lansoprazole in children less than 1 year of age with use in other age groups. It is safe to use oral lansoprazole to treat heartburn and erosive esophagitis in people between 1 and 17 years of age.
Studies on lansoprazole for injection have been done only in adult patients, and there is no specific information comparing use of lansoprazole for injection in children with use in other age groups.
Older adults—In studies done to date that have included older adults, lansoprazole did not cause different side effects or problems than it did in younger adults.
Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking lansoprazole, it is especially important that your health care professional know if you are taking any of the following:
Proper Use of This Medicine
Take oral lansoprazole before a meal, preferably in the morning .
For Delayed-Release Capsules: Swallow the capsule whole. Do not crush, break, or chew the capsule . If you cannot swallow the capsule whole, you may open it and sprinkle the granules contained in the capsule on one tablespoonful of applesauce and swallow it immediately; or you may mix the granules in some fruit or vegetable juice and drink it immediately. Juices you may use include apple, cranberry, grape, orange, pineapple, prune, tomato, and V-8 vegetable juice. Do not chew or crush the granules .
For Delayed-Release Oral Suspension: Empty the packet contents into a container containing 2 tablespoons of water. Stir well and drink immediately. If any of the content remains after drinking, add more water and drink immediately. If you have enteral administration tubes, do not take this medicine through them.
For Delayed-Release Orally Disintegrating Tablets: Do not chew . Place on tongue and allow to disintegrate, with or without water, until particles can be swallowed
Take this medicine for the full time of treatment, even if you begin to feel better . Also, keep your appointments with your doctor for check-ups so that your doctor will be better able to tell you when to stop taking this medicine.
Dosing—The dose of lansoprazole will be different for different patients. Follow your doctor"s orders or the directions on the label . The following information includes only the average doses of lansoprazole. If your dose is different, do not change it unless your doctor tells you to do so.
The number of doses you take each day and the length of time you take the medicine depend on the medical problem for which you are taking lansoprazole .
Missed dose—If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage—To store this medicine:
Precautions While Using This Medicine
It is important that your doctor check your progress at regular intervals . If your condition does not improve, or if it becomes worse, discuss this with your doctor.
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Diarrhea; skin rash or itching
Abdominal or stomach pain; increased or decreased appetite; joint pain; nausea; vomiting
Anxiety; cold or flu-like symptoms; constipation; increased cough; mental depression; muscle pain; rectal bleeding; unusual bleeding or bruising
Incidence not known
abdominal tenderness; back, leg, or stomach pains; bleeding gums; blistering, peeling, loosening of skin; bloating; bloody, black, or tarry stools; change in mental status; chest pain; chills; clay colored stools; constipation; cough or hoarseness; dark or bloody urine; difficulty breathing; difficulty speaking; difficulty swallowing; fast heartbeat; fatigue; fever; general body swelling; high fever; hives; indigestion; loss of appetite; lower back or side pain; nosebleeds; painful or difficult urination; pains in stomach, side, or abdomen, possibly radiating to the back; pale skin; puffiness or swelling of the eyelids or around the eyes, face, lips or tongue; red irritated eyes; pinpoint red spots on skin; red skin lesions, often with a purple center; seizures; shortness of breath; sore throat; sores, ulcers, or white spots on lips or in mouth; swelling of feet or lower legs; swollen or painful glands; tightness in chest; unusual tiredness or weakness; wheezing; yellowing of the eyes or skin
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at injection site; mild nausea
acid or sour stomach; bad, unusual or unpleasant (after)taste; belching; burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings; change in taste; feeling faint, dizzy, or light-headedness; feeling of warmth or heat; flushing or redness of skin, especially on face and neck; heartburn; indigestion; mild diarrhea; mild headache; mild vomiting; stomach discomfort, upset or pain; sweating
Incidence not known
difficulty in speaking; decrease in frequency of urination; decrease in urine volume; difficulty in passing urine [dribbling]
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.
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