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Analpram-HC, Enzone, Epifoam, Pramosone, Proctocream HC, Proctofoam HC, Rectocort HC, Zone-A, Zone-A Forte, |Pramosone

Pramosone

Generic Name: hydrocortisone and pramoxine topical (hye droe KOR tih sone and prah MOX een)
Brand Names: Analpram-HC, Enzone, Epifoam, Pramosone, Proctocream HC, Proctofoam HC, Rectocort HC, Zone-A, Zone-A Forte

What is hydrocortisone and pramoxine topical?

Hydrocortisone is a steroid medication. Hydrocortisone topical reduces or inhibits the actions of chemicals in the body that cause inflammation, redness, swelling, and itching.

Pramoxine is a topical anesthetic. Pramoxine causes a loss of feeling in the skin.

Together, hydrocortisone and pramoxine are used to treat minor skin irritations, anal itching, hemorrhoids, and pain from episiotomy.

Hydrocortisone and pramoxine topical may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about hydrocortisone and pramoxine topical?

Contact your healthcare provider if your symptoms worsen or do not improve within 7 days. Do not use hydrocortisone and pramoxine topical for longer than 14 days without first talking to your doctor.

What should I discuss with my healthcare provider before using hydrocortisone and pramoxine topical?

Before using hydrocortisone and pramoxine topical, talk to your doctor if you have

• chickenpox, herpes, or tuberculosis infection;

• diabetes;

• thinning of the skin; or

• infection near the site of use.

You may not be able to use hydrocortisone and pramoxine topical, or you may require a dosage adjustment or special monitoring during use.

How should I use hydrocortisone and pramoxine topical?

Hydrocortisone and pramoxine topical is intended for topical use on the skin or in the rectum. Do not take the medication by mouth. Do not get this medication if the eyes. Wash your hands before and after application of the medication.

Using the fingers or a tissue, apply a thin film of the cream, ointment, or lotion to the affected area and rub in gently.

To apply the foam externally, shake the container vigorously for 5 to 10 seconds before each use. Press down on the top several times until foam appears. Dispense the foam onto a tissue or cloth and gently rub into the affected area. The fingers should not be used to apply the foam. Rinse the container and cap after each use.

To apply the foam into the rectum using the rectal applicator:

• Hold the container upright and gently place the tip of the applicator onto the nose of the container cap.

• Pull the applicator plunger past the fill line on the applicator barrel.

• Hold the container and applicator at eye level. Place your index and middle fingers on the arms of the container cap and the thumb beneath container. Support the applicator with your other hand. Prime the container by pressing down firmly on the arms of the cap and then release. It usually requires 1 or 2 pumps for foam to appear. The first time you prime the pump a burst of air may come out of the container.

• To fill the applicator, press down firmly on cap flanges, hold for 1 to 2 seconds, and release. Wait 5 to 10 seconds to allow foam to expand in the applicator. Repeat until the foam reaches the fill line. It may take 3 or 4 pumps to reach the fill line. Remove the applicator from the container cap.

• Hold the applicator firmly. Place your index finger over the plunger. Gently insert the tip of the applicator into the anus. Once in place, push plunger to expel foam, then withdraw applicator. Apply to the anus only with the applicator provided with the foam.

• The applicator parts and container and cap should be pulled apart and rinsed with warm water after each use.

Use care to avoid inhaling the vapors when using hydrocortisone and pramoxine topical foam.

Contact your healthcare provider if your symptoms worsen or do not improve within 7 days. Do not use hydrocortisone and pramoxine topical for longer than 14 days without first talking to your doctor.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and apply the next regularly scheduled dose. Do not use a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

An overdose of hydrocortisone and pramoxine topical is not likely to threaten life.

If the medication has been ingested, or if a large amount is used over a large area and side effects are being experienced, call an emergency room or a poison control center for advice.

What should I avoid while using hydrocortisone and pramoxine topical?

Use care to avoid inhaling the vapors when using hydrocortisone and pramoxine topical foam.

Do not use other topical medications on the affected area during treatment with hydrocortisone and pramoxine topical without first talking to your doctor.

Hydrocortisone and pramoxine topical side effects

No serious systemic side effects are expected from the use of hydrocortisone and pramoxine topical unless a large amount of the medication is used for a long period of time. If the drug is being absorbed into the system, you may experience blurred vision, halos around lights, an irregular heartbeat, insomnia, mood changes, weight gain, or fatigue. If you experience any unusual side effects, notify your doctor.

Less serious side effects are more likely to occur. You may experience some redness, burning, itching, or irritation at the application site. Continue to use hydrocortisone and pramoxine topical and talk to your doctor about any side effects you experience.

Long-term treatment with hydrocortisone and pramoxine topical may cause decreased wound healing, thinning of the skin, increased skin irritation, or skin infection.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect hydrocortisone and pramoxine topical?

Do not use other topical medications on the affected area during treatment with hydrocortisone and pramoxine topical without first talking to your doctor.

Drugs other than those listed here may also interact with hydrocortisone and pramoxine topical. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

• Your pharmacist has additional information about hydrocortisone and pramoxine written for health professionals that you may read.

What does my medication look like?

Hydrocortisone and pramoxine topical is available with a prescription and over-the-counter under several brand names. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.