Pimecrolimus

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Pimecrolimus


Generic Name: Pimecrolimus (pim-e-KROE-li-mus)
Brand Name: Elidel

The long-term safety of Pimecrolimus has not been determined. Because rare cases of cancer (eg, lymphoma, skin cancer) have been reported, continuous long-term use should be avoided and the application of Pimecrolimus should be limited to the affected areas. Pimecrolimus should not be used in children younger than 2 years old.


Pimecrolimus is used for:

Treating atopic dermatitis, also known as eczema, in patients who cannot take or whose symptoms do not respond to other treatments.

Pimecrolimus is a topical immunomodulator, which means it modulates or "changes" the body"s immune system in some way. In eczema, it works by preventing the activation of certain immune cells and blocks the release of certain chemicals that cause inflammation, redness, and itching of the skin.

Do NOT use Pimecrolimus if:

  • you are allergic to any ingredient in Pimecrolimus

Contact your doctor or health care provider right away if any of these apply to you.

Before using Pimecrolimus :

Some medical conditions may interact with Pimecrolimus . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have Netheron syndrome
  • if you have any bacterial (impetigo) or viral skin infections, such as chickenpox, shingles, herpes, cold sores, or warts
  • if you are receiving any form of light therapy (phototherapy, UVA, UVB) on your skin
  • if you are using any other type of skin product

Some MEDICINES MAY INTERACT with Pimecrolimus . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Macrolide antibiotics (eg, erythromycin), azole antifungals (eg, ketoconazole), or calcium channel blockers (eg, diltiazem) because they may increase the risk of Pimecrolimus "s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Pimecrolimus may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Pimecrolimus :

Use Pimecrolimus as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Pimecrolimus comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Pimecrolimus refilled.
  • Wash your hands before using Pimecrolimus .
  • Use Pimecrolimus only on your skin. Apply a thin layer to the affected skin twice daily as directed by your health care provider. You can apply it on affected areas on all skin surfaces, including your face, head, and neck. Avoid contact with your eyes.
  • If your doctor recommends using moisturizers, apply them after using Pimecrolimus .
  • Unless you are treating your hands, wash your hands with soap and water after applying Pimecrolimus to remove any cream left on the hands.
  • Do not cover the skin being treated with bandages, dressings, or wraps. However, you can wear normal clothing.
  • Do not bathe, shower, or swim right after applying Pimecrolimus . This could wash off the cream.
  • Do not apply Pimecrolimus to open wounds or infected areas.
  • Do not use more medicine than prescribed unless advised to do so by your doctor.
  • If you miss a dose of Pimecrolimus , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Pimecrolimus .

Important safety information:

  • Pimecrolimus is for external use only. Do not get it in your eyes, nose, or mouth. If you get it in your eyes, rinse at once with cool tap water.
  • Contact your doctor if your condition worsens, does not improve after 6 weeks of using Pimecrolimus , or if a feeling of warmth or a burning sensation at the application site is severe or persists for more than 1 week.
  • Pimecrolimus may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Pimecrolimus . Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Pimecrolimus may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
  • Pimecrolimus should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pimecrolimus while you are pregnant. It is not known if Pimecrolimus is found in breast milk. Do not breast-feed while you are using Pimecrolimus .

Possible side effects of Pimecrolimus :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cough; flu syndrome; headache; irritation, feeling of warmth, itching, or burning sensation at the application site; skin infection (increased redness or swelling, fever); skin sensitivity to sunlight; sore throat; upper abdominal pain; upper respiratory tract infection; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever; swollen lymph nodes (glands); warts, sores, or other new growths on the skin, including herpes skin infections (eg, cold sores, chickenpox, shingles); worsening of condition.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Pimecrolimus :

Store Pimecrolimus at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not freeze. Do not leave Pimecrolimus in your car in cold or hot weather. Make sure the cap on the tube is tightly closed. Keep Pimecrolimus out of the reach of children and away from pets.

General information:

  • If you have any questions about Pimecrolimus , please talk with your doctor, pharmacist, or other health care provider.
  • Pimecrolimus is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Pimecrolimus . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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