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Persantine, |Persantine

Persantine

Generic Name: dipyridamole (dye peer ID a mole)
Brand Names: Persantine

What is dipyridamole?

Dipyridamole stops platelets (substances in your blood necessary for blood clotting) from sticking together or attaching to prosthetic heart valve surfaces.

Dipyridamole is used to prevent the formation of blood clots following heart valve replacement surgery.

Dipyridamole may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about dipyridamole?

What should I discuss with my healthcare provider before taking dipyridamole?

Dipyridamole should be used cautiously if you have abnormally low blood pressure.

How should I take dipyridamole?

Take dipyridamole exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

For best results, take dipyridamole on an empty stomach. However, it can be taken with food if it upsets your stomach.

What happens if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication. A double dose could be dangerous.

What happens if I overdose?

Symptoms of a dipyridamole overdose include slurred speech, loss of balance, vomiting, diarrhea, and lethargy or decreased movement.

What should I avoid while taking dipyridamole?

Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, Nuprin, others), naproxen (Aleve, Naprosyn, Anaprox), or ketoprofen (Orudis, Orudis KT) during therapy with dipyridamole. The combination could lead to bleeding, especially in your stomach. Talk to your pharmacist or doctor before taking any over-the-counter or prescription medications for pain, inflammation (including arthritis), or fever.

Dipyridamole side effects

Other, less serious side effects may be more likely to occur. Continue to take dipyridamole and talk to your doctor if you experience

• dizziness;

• upset stomach, nausea, or vomiting;

• headache; or

• a rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect dipyridamole?

Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, Nuprin, others), naproxen (Aleve, Naprosyn, Anaprox), and ketoprofen (Orudis, Orudis KT) could lead to bleeding if taken during dipyridamole therapy. Talk to your pharmacist or doctor before taking any over-the-counter or prescription medications for pain, inflammation (including arthritis), or fever. Other commonly used NSAIDs include diclofenac (Voltaren, Cataflam), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), and tolmetin (Tolectin).

During therapy with dipyridamole, you may also be taking warfarin (Coumadin). This medicine interacts with many other drugs, so use caution and follow the instructions of your doctor and pharmacist.

Drugs other than those listed here may also interact with dipyridamole. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

• Your pharmacist has additional information about dipyridamole written for health professionals that you may read.

What does my medication look like?

Dipyridamole is available with a prescription under the brand name Persantine. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Persantine 25 mg--round, orange, sugar-coated tablets

• Persantine 50 mg--round, orange, sugar-coated tablets

• Persantine 75 mg--round, orange, sugar-coated tablets

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.