Pepcid Solution

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Pepcid Solution


Generic Name: Famotidine InjectionSolution (fa-MOE-tih-deen)
Brand Name: Pepcid

Pepcid Solution is used for:

Treating and preventing ulcers of the stomach and upper small intestine; conditions that cause increased acid secretion (eg, Zollinger-Ellison syndrome); gastroesophageal reflux disease (GERD, or the bubbling of stomach contents into the food pipe, which causes heartburn); and esophagitis, or inflammation of the food pipe due to acid reflux. It may also be used for certain conditions as determined by your doctor, which may not be listed in the professional package insert.

Pepcid Solution is an H2 (histamine) blocker. It works by reducing stomach acid by blocking one of the chemicals (histamine) that stimulates the release of acid into the stomach.

Do NOT use Pepcid Solution if:

  • you are allergic to any ingredient in Pepcid Solution or other acid reducers (H2 blockers).

Contact your doctor or health care provider right away if any of these apply to you.

Before using Pepcid Solution:

Some medical conditions may interact with Pepcid Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines or other substances
  • if you will be administering Pepcid Solution to a newborn
  • if you have kidney or liver disease

Some MEDICINES MAY INTERACT with Pepcid Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Cephalosporins (eg, cephalexin), itraconazole, or ketoconazole because the effectiveness may be decreased by Pepcid Solution

This may not be a complete list of all interactions that may occur. Ask your health care provider if Pepcid Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Pepcid Solution:

Use Pepcid Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Pepcid Solution is usually administered as an injection at your doctor"s office, hospital, or clinic. If you are using Pepcid Solution at home, a health care professional will provide detailed instructions for its appropriate use. Ask any questions that you may have about Pepcid Solution or giving injections.
  • If Pepcid Solution contains particles, is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Keep this product, as well as syringes and needles, out of the reach of children. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for proper disposal.
  • You may take antacids with Pepcid Solution unless directed otherwise by our doctor.
  • Continue to use Pepcid Solution even if you feel well. Do not miss any doses.
  • If you miss a dose of Pepcid Solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Pepcid Solution.

Important safety information:

  • Pepcid Solution may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Pepcid Solution. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Never self-diagnose or self-treat ulcers with this or any other medicine.
  • Notify your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds.
  • You may need to make significant diet and lifestyle changes to help treat and prevent ulcers and other digestive problems, including stress-reduction programs, exercise, and diet changes.
  • LAB TESTS, including liver function, kidney function, and complete blood count, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Pepcid Solution with caution in the ELDERLY because they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Pepcid Solution during pregnancy. Pepcid Solution is excreted in breast milk. Do not breast-feed while using Pepcid Solution.

Possible side effects of Pepcid Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; headache.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions (seizures).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Pepcid Solution:

Store the injection that is NOT already mixed in the refrigerator at 36 to 46 degrees F (2 to 8 degrees C). Store the premixed injection at room temperature, 77 degrees F (25 degrees C). Avoid exposure of the premixed product to excessive heat. If the injection is not used immediately after preparation, refrigerate the diluted solutions and use within 48 hours. Keep Pepcid Solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Pepcid Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when it is full.
  • Pepcid Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • Do not use Pepcid Solution for other health conditions.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Pepcid Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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