Pediarix

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Pediarix, |Pediarix

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Pediarix

Generic Name: diphtheria, hepatitis B, pertussis (acellular), polio, and tetanus vaccine (dif THEER ee a, hep a TYE tis B, per TUS iss, POE lee oh, and TET nus)
Brand Names: Pediarix

What is diphtheria, hepatitis B, pertussis acellular, polio, and tetanus vaccine?

Diphtheria, pertussis, and tetanus are serious diseases caused by bacteria.

Diphtheria causes a thick coating in the nose, throat, and airways. It can lead to breathing problems, paralysis, heart failure, or death.

Pertussis (whooping cough) causes coughing so severe that it interferes with eating, drinking, or breathing. These spells can last for weeks and can lead to pneumonia, seizures (convulsions), brain damage, and death.

Tetanus (lockjaw) causes painful tightening of the muscles, usually all over the body. It can lead to "locking" of the jaw so the victim cannot open the mouth or swallow. Tetanus leads to death in about 1 out of 10 cases.

Hepatitis B and polio are serious diseases caused by virus.

Hepatitis B is a disease of the liver that is spread through blood or bodily fluids, sexual contact or sharing IV drug needles with an infected person, or during childbirth when the mother is infected. Hepatitis causes inflammation of the liver, vomiting, and jaundice (yellowing of the skin or eyes). Hepatitis can lead to liver cancer, cirrhosis, or death.

Polio affects the central nervous system and spinal cord. It can cause muscle weakness and paralysis. Polio is a life-threatening condition because it can paralyze the muscles that help you breathe.

Diphtheria, hepatitis B, pertussis, and polio are spread from person to person. Tetanus enters the body through a cut or wound. Vaccines for these diseases contain a small amount of the bacteria or virus, which helps the body develop immunity to the disease.

The diphtheria, hepatitis B, pertussis acellular, polio, and tetanus vaccine is used to help prevent these diseases in children.

What is the most important information I should know about diphtheria, hepatitis B, pertussis acellular, polio, and tetanus vaccine?

This vaccine is given in a series of 3 shots. The first shot is usually given when the child is 2 months old. The booster shots are then given at 4 months and 6 months of age. Your child"s individual booster schedule may be different from these guidelines. Follow your doctor"s instructions.

Your child can still receive a vaccine if he or she has a cold or fever. However, in the case of moderate or severe illness, wait until the child recovers before getting this vaccine.

Your child should not receive a booster vaccine if he or she had a life-threatening allergic reaction after the first shot.

Keep track of any and all side effects your child has after receiving this vaccine. When the child receives a booster dose, you will need to tell the doctor if the previous shots caused any side effects. Getting diphtheria, hepatitis, pertussis, polio, or tetanus disease is much more dangerous to your child"s health than receiving this vaccine. However, like any medicine, this vaccine can cause side effects. The risk of serious side effects is extremely low.

What should I discuss with my healthcare provider before receiving diphtheria, hepatitis B, pertussis acellular, polio, and tetanus vaccine?

Your child should not receive this vaccine if the child is allergic to yeast, neomycin, or polymyxin B, or if the child has:
  • a disorder or disease affecting the brain;

  • uncontrolled epilepsy or other seizure disorder; or

  • a neurologic disorder.

Your child should not receive this vaccine if he or she has ever received a previous diphtheria, hepatitis B, pertussis, polio, or tetanus vaccine that caused any of the following:
  • a very high fever;

  • excessive crying for 3 hours or longer;

  • fainting or going into shock;

  • Guillian-Barre syndrome (within 6 weeks after receiving a tetanus shot);

  • seizure (convulsions); or

  • a severe skin reaction.

If your child has had any of these conditions after receiving a previous diphtheria, hepatitis B, pertussis, polio, or tetanus vaccine separately, he or she may not be able to receive this combination vaccine.

Before receiving this vaccine, tell the doctor if your child has:

  • a bleeding or blood clotting disorder such as hemophilia or easy bruising;

  • a history of seizures;

  • an allergy to latex rubber;

  • a weak immune system caused by disease or by taking certain medicines or receiving cancer treatments;

  • if the child is taking a blood thinner such as warfarin (Coumadin); or

  • if it has been less than 6 weeks since the child last received a vaccine.

Your child can still receive a vaccine if he or she has a cold or fever. However, in the case of moderate or severe illness, wait until the child recovers before getting this vaccine.

How is the diphtheria, hepatitis B, pertussis acellular, polio, and tetanus vaccine given?

This vaccine is given as an injection into a muscle. Your child will receive this injection in a doctor"s office or other clinic setting.

This vaccine is given in a series of 3 shots. The first shot is usually given when the child is 2 months old. The booster shots are then given at 4 months and 6 months of age. Your child"s individual booster schedule may be different from these guidelines. Follow your doctor"s instructions.

Your doctor may recommend reducing fever and pain by giving the child an aspirin-free pain reliever such as acetaminophen (Tylenol) or ibuprofen (Motrin, Advil, and others) when the shot is given and for the next 24 hours. Follow your doctor"s instructions about how much of this medicine you should give. It is especially important to prevent fever from occurring in a child who has a seizure disorder such as epilepsy.

What happens if I miss a dose?

Contact your doctor if you miss a scheduled booster vaccine.

What happens if I overdose?

An overdose of this vaccine is unlikely to occur.

What should I avoid before or after getting diphtheria, hepatitis B, pertussis acellular, polio, and tetanus vaccine?

There are no restrictions on food, beverages, or activity before or after receiving this vaccine unless your doctor has told you otherwise.

What are the possible side effects of diphtheria, tetanus, and pertussis acellular, and tetanus vaccine?

Your child should not receive a booster vaccine if he or she had a life-threatening allergic reaction after the first shot.

Keep track of any and all side effects your child has after receiving this vaccine. When the child receives a booster dose, you will need to tell the doctor if the previous shots caused any side effects. Getting diphtheria, hepatitis, pertussis, polio, or tetanus disease is much more dangerous to your child"s health than receiving this vaccine. However, like any medicine, this vaccine can cause side effects. The risk of serious side effects is extremely low.

Get emergency medical help if your child has any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if the child has any of the following serious side effects:

  • extreme drowsiness, fainting;

  • fussiness, irritability, crying for an hour or longer;

  • seizure (black-out or convulsions); or

  • high fever (can occur for up to 4 days after the vaccine).

Other less serious side effects are more likely to occur, such as:

  • redness, pain, tenderness, or swelling where the shot was given;

  • mild fever;

  • mild fussiness or crying;

  • joint pain, body aches;

  • drowsiness; or

  • vomiting.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome to the child.

What other drugs will affect diphtheria, hepatitis B, pertussis acellular, polio, and tetanus vaccine?

Before receiving this vaccine, tell the doctor about all other vaccines your child has received.

There may be other drugs that can affect this vaccine. Tell your doctor about all the prescription and over-the-counter medications your child has received. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your doctor or pharmacist may have information about this vaccine written for health professionals that you may read. You may also find additional information from your local health department or the Centers for Disease Control and Prevention.

  • Remember, keep this and all other medicines out of the reach of children, never share medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.05. Revision Date: 2/22/07 11:22:24 AM.



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