Papain/Urea Ointment

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Papain/Urea Ointment


Generic Name: Papain/Urea Ointment (pap-ANE/you-REE-ah)
Brand Name: Examples include Accuzyme and Ethezyme

Papain/Urea Ointment is used for:

Removing dead tissue and thinning the pus in lesions such as ulcers, burns, wounds, and carbuncles.

Papain/Urea Ointment is a debriding agent. It works by helping the breakdown of dead skin and pus, which helps improve the recovery time of open wounds.

Do NOT use Papain/Urea Ointment if:

  • you are allergic to any ingredient in Papain/Urea Ointment

Contact your doctor or health care provider right away if any of these apply to you.

Before using Papain/Urea Ointment:

Some medical conditions may interact with Papain/Urea Ointment. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Papain/Urea Ointment. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Medicine containing silver, lead, or mercury because the effectiveness of Papain/Urea Ointment may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Papain/Urea Ointment may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Papain/Urea Ointment:

Use Papain/Urea Ointment as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Papain/Urea Ointment is for external use only.
  • Before each use of Papain/Urea Ointment, clean the affected area with saline or another mild wound cleansing solution. Do not use hydrogen peroxide.
  • Apply Papain/Urea Ointment directly to the lesion, cover with appropriate dressing (eg, bandages), and secure into place. Wash the lesion each time the dressing is changed.
  • Change wound dressings according to the schedule set by your doctor.
  • If irritation occurs, talk with your doctor about changing the dressings more often.
  • If you miss a dose of Papain/Urea Ointment, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Papain/Urea Ointment.

Important safety information:

  • Papain/Urea Ointment is for external use only. Do not get it in the eyes or mouth. If you get Papain/Urea Ointment in the eyes, rinse them immediately with a generous amount of cool water.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Papain/Urea Ointment, discuss with your doctor the benefits and risks of using Papain/Urea Ointment during pregnancy. It is unknown if Papain/Urea Ointment is excreted in breast milk. If you are or will be breast-feeding while you are using Papain/Urea Ointment, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Papain/Urea Ointment:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild skin irritation; temporary burning sensation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Papain/Urea Ointment:

Store Papain/Urea Ointment in a cool place, between 46 and 59 degrees F (8 and 15 degrees C). Do not refrigerate. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Papain/Urea Ointment out of the reach of children and away from pets.

General information:

  • If you have any questions about Papain/Urea Ointment, please talk with your doctor, pharmacist, or other health care provider.
  • Papain/Urea Ointment is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Papain/Urea Ointment. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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