Oseltamivir phosphate
 Oseltamivir Phosphate

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|Oseltamivir phosphate Oseltamivir Phosphate

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Oseltamivir phosphate

Generic name: Oseltamivir phosphate
Brand names: Tamiflu

Why is Oseltamivir phosphate prescribed?

Oseltamivir phosphate speeds recovery from the flu. When started during the first 2 days of the illness, it hastens improvement by at least a day. It also can prevent the flu if treatment is started within 2 days after exposure to a flu victim. Oseltamivir phosphate is one of a new class of antiviral drugs called neuraminidase inhibitors.

As the flu virus takes hold in the body, it forms new copies of itself and spreads from cell to cell. Neuraminidase inhibitors fight the virus by preventing the release of new copies from infected cells. The other drug in this class, Relenza, is taken by inhalation. Oseltamivir phosphate is taken in liquid or capsule form.

Most important fact about Oseltamivir phosphate

Oseltamivir phosphate can prevent the flu as long as you continue taking Oseltamivir phosphate, but getting a yearly flu shot is still the best way of avoiding the disease entirely. For older adults, those in high-risk situations such as health-care work, and people with an immune deficiency or respiratory disease, vaccination remains a must.

How should you take Oseltamivir phosphate?

To provide any benefit, Oseltamivir phosphate must be started within two days of the onset of symptoms, or exposure to the flu. If you have the flu, continue taking it twice daily for 5 days, even if you start to feel better. To prevent the flu, take it once a day for at least 7 days. Protection lasts as long as you take the drug.

If Oseltamivir phosphate upsets your stomach, try taking it with food. Shake the liquid suspension before each use.

--If you miss a dose...

Take it as soon as possible. If it is within two hours of your next dose, skip the missed dose and go back to your regular schedule.

--Storage instructions...

Store at room temperature. Keep the blister package dry. Use the liquid suspension within 10 days. It should be refrigerated, but do not freeze.

What side effects may occur?

Most problems noted during tests of Oseltamivir phosphate were indistinguishable from the symptoms of flu. Here are the reactions that showed up more frequently in patients taking the drug.

  • More common side effects may include:
    Abdominal pain, asthma, bronchitis, cough, diarrhea, ear infection, fatigue, headache, insomnia, nausea, nosebleed, vertigo, vomiting

Why should Oseltamivir phosphate not be prescribed?

If Oseltamivir phosphate gives you an allergic reaction, avoid it in the future.

Special warnings about Oseltamivir phosphate

If you have kidney disease, the doctor may have to cut your daily dose of Oseltamivir phosphate in half.

The effectiveness of Oseltamivir phosphate has not been established for people with weakened immune systems. The drug has not been studied in people with liver disease.

Oseltamivir phosphate works only on the flu virus. It won"t stop bacterial infections that may have flu-like symptoms or bacterial infections that may develop while you have the flu. If your symptoms persist, check with your doctor.

Possible food and drug interactions when taking Oseltamivir phosphate

No interactions have been reported.

Special information if you are pregnant or breastfeeding

It is not known whether Oseltamivir phosphate is completely safe during pregnancy. If you are pregnant or plan to become pregnant, inform your doctor before taking Oseltamivir phosphate. Oseltamivir phosphate may appear in breast milk and could affect a nursing infant. Taking it while breastfeeding is usually not recommended.

Recommended dosage

ADULTS AND CHILDREN 13 AND OLDER

Treatment of Influenza

The usual dosage is 75 milligrams taken twice daily (morning and evening) for 5 days. If you have kidney disease, take a 75-milligram dose once a day.

Prevention of Influenza

The usual dosage is 75 milligrams taken once a day for at least 7 days. If there is a general outbreak of the flu in your community, your doctor may recommend that you continue taking Oseltamivir phosphate for up to 6 weeks. If you have kidney disease, take a 75-milligram capsule every other day, or 30 milligrams of liquid once a day.

CHILDREN 1 TO 12

Treatment of Influenza

Doses should be given twice daily for 5 days using the dispenser that comes with the liquid suspension. Each dose is determined by the child"s weight:

Under 33 pounds: 30 milligrams
33 to 55 pounds: 45 milligrams
51 to 88 pounds: 60 milligrams
Over 88 pounds: 75 milligrams
Oseltamivir phosphate should not be used to treat the flu in children under 1 year old.

Prevention of Influenza

Oseltamivir phosphate"s ability to prevent the flu in children under age 13 has not been established.

Overdosage

High doses of Oseltamivir phosphate can cause nausea and vomiting. As with any medication, if you suspect an overdose, seek emergency medical treatment immediately.





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