Opana ER
 Opana ER

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Opana, Opana ER, |Opana ER Opana ER

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Opana ER

Generic Name: oxymorphone (ox ee MOR fone)
Brand Names: Opana, Opana ER

What is oxymorphone?

Oxymorphone is a narcotic pain reliever.

Oxymorphone is used to treat moderate to severe pain.

Oxymorphone may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about oxymorphone?

Do not take oxymorphone with alcohol, other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result. You may have withdrawal symptoms when you stop using this medication after using it over a long period of time. Do not stop using oxymorphone suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely. Oxymorphone may be habit-forming and should be used only by the person it was prescribed for. Oxymorphone should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Keep track of how many tablets have been used from each new bottle of this medicine. Oxymorphone is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What should I discuss with my doctor before taking oxymorphone?

Do not take oxymorphone if you have severe liver disease, or if you have ever had an allergic reaction to codeine, morphine, or similar pain medicines.

Before taking oxymorphone, tell your doctor if you have:

  • asthma, COPD, sleep apnea, or other breathing disorders;

  • intestinal blockage;

  • liver disease;
  • kidney disease;
  • underactive thyroid;

  • curvature of the spine;

  • a history of head injury or brain tumor;

  • epilepsy or other seizure disorder;

  • low blood pressure;

  • gallbladder or pancreas disease;

  • Addison"s disease or other adrenal gland disorders;

  • enlarged prostate, urination problems;

  • mental illness; or

  • a history of drug or alcohol addiction.

If you have any of these conditions, you may not be able to use oxymorphone, or you may need a dosage adjustment or special tests during treatment.

Oxymorphone may be habit-forming and should be used only by the person it was prescribed for. Oxymorphone should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Keep track of how many tablets have been used from each new bottle of this medicine. Oxymorphone is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether oxymorphone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more sensitive to the effects of this medicine.

How should I take oxymorphone?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Too much oxymorphone could be very harmful. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Take oxymorphone on an empty stomach, at least 1 hour before or 2 hours after eating. Do not crush, chew, break, or dissolve an extended-release tablet (Opana ER). Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time, which could cause a life-threatening overdose. You may have withdrawal symptoms when you stop using this medication after using it over a long period of time. Do not stop using oxymorphone suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely. Drink 6 to 8 full glasses of water daily to help prevent constipation while you are taking oxymorphone. Ask your doctor about ways to increase the fiber in your diet. Do not use a stool softener (laxative) without first asking your doctor. Store this medication at room temperature, away from heat and moisture.

After you have stopped taking this medication, flush any unused pills down the toilet.

What happens if I miss a dose?

Since oxymorphone is sometimes used as needed, you may not be on a dosing schedule. If you are using the medication regularly, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of oxymorphone can be fatal.

Symptoms of an oxymorphone overdose may include extreme drowsiness, muscle weakness, confusion, cold and clammy skin, pinpoint pupils, shallow breathing, slow heart rate, blue lips or fingernails, fainting, or coma.

What should I avoid while using oxymorphone?

Do not drink alcohol while you are taking oxymorphone. Dangerous side effects or death can occur when alcohol is combined with oxymorphone. Check the label of any other medicines you take to be sure they do not contain alcohol.

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by oxymorphone, which could result in extreme drowsiness or coma.

Oxymorphone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Oxymorphone side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
  • shallow breathing;

  • seizure (convulsions);

  • cold, clammy skin;

  • confusion;

  • severe weakness or dizziness; or

  • feeling light-headed, fainting.

Other, less serious side effects may be more likely to occur, such as:

  • constipation;

  • drowsiness;

  • nausea, vomiting, diarrhea, loss of appetite;

  • dizziness, headache;

  • dry mouth;

  • sweating;

  • itching; or

  • sleep problems (insomnia).

If you stop taking oxymorphone suddenly after using it over a long period of time, you may have withdrawal symptoms, including: watery eyes, runny nose, chills, increased sweating, yawning, feeling restless or irritable, blurred vision, loss of appetite, nausea, vomiting, diarrhea, stomach pain, joint or muscle pain, fast heart rate, or trouble sleeping.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect oxymorphone?

Do not take oxymorphone with alcohol, other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.

Before taking oxymorphone, tell your doctor if you are using any of the following drugs:

  • narcotic pain medicines such as pentazocine (Talwin), nalbuphine (Nubain), butorphanol (Stadol), buprenorphine (Buprenex, Subutex);

  • atropine (Donnatal, and others);

  • belladonna;

  • clidinium (Quarzan);

  • dicyclomine (Bentyl);

  • glycopyrrolate (Robinul);

  • hyoscyamine (Anaspaz, Cystospaz, Levsin);

  • mepenzolate (Cantil);

  • methantheline (Provocholine);

  • methscopolamine (Pamine);

  • propantheline (Pro-Banthine); or

  • scopolamine (Transderm-Scop).

If you are using any of these drugs, you may not be able to use oxymorphone, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect oxymorphone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist has additional information about oxymorphone written for health professionals that you may read.

What does my medication look like?

Oxymorphone is available with a prescription under the brand name Opana. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Opana 5 mg--blue, round tablet

  • Opana 10 mg--red, round tablet

  • Opana ER 5 mg--pink, octagon film-coated tablet

  • Opana ER 10 mg--light orange, octagon film-coated tablet

  • Opana ER 20 mg--light green, octagon film-coated tablet

  • Opana ER 40 mg--yellow, octagon film-coated tablet

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 5.02. Revision Date: 7/12/06 4:26:54 PM.



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