nitisinone
 Nitisinone

drug-information.ru

Orfadin, |nitisinone Nitisinone

Drugs search, click the first letter of a drug name:


| A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 1 | 2 | 3 | 4 | 5 | 6 | 8 | 9  Home

nitisinone

Generic Name: nitisinone (ni TIZ i none)
Brand Names: Orfadin

What is nitisinone?

Nitisinone is used to treat a rare genetic condition called hereditary tyrosinemia type 1 (HT-1). HT-1 is a metabolic disorder that occurs when the body does not produce enough of an enzyme that breaks down proteins from certain foods. This condition occurs most often in young babies. The symptoms of HT-1 include unusual bleeding and signs of liver failure, such as dark urine, jaundice (yellowing of the skin or eyes), sudden stomach pain, nausea, vomiting, diarrhea, and fatigue.

Nitisinone works by preventing the body from breaking down an amino acid called tyrosine and by keeping other toxic substances from building up and causing harm to your liver or kidneys.

What is the most important information I should know about nitisinone?

Nitisinone is only part of a complete program of treatment that also includes a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you must avoid to help control your condition.

You may experience side effects that are caused by nitisinone. Similar side effects may also be caused by your diet. Call your doctor immediately if you have jaundice (yellowing of the skin or eyes), unusual bleeding, vision changes, or eye redness, pain, burning, or sensitivity to light.

What should I discuss with my health care provider before taking nitisinone?

Before taking nitisinone, tell your doctor if you have eye pain, redness, or swelling, or if your eyes are more sensitive to light than usual. You may need to have an eye examination.

While you are taking nitisinone, your doctor may recommend regular visits to check your liver with blood tests and ultrasounds or CT scans.

Some side effects may result from not properly following your diet plan and consuming restricted foods or beverages. Call your doctor if you develop eye redness, pain, burning, or sensitivity to light; painful overgrowth of skin on the palms of your hands or the soles of your feet; changes in behavior; or delayed developmental milestones in a baby such as walking, talking, sitting up, or rolling over. Nitisinone is in the FDA pregnancy category C. This means that it is not known whether nitisinone will be harmful to an unborn baby. Although it is unlikely that a child taking nitisinone would become pregnant, the medicine may also be used in women of child-bearing age. Do not take nitisinone without telling your doctor if you are pregnant. It is not known whether nitisinone passes into breast milk. Do not use nitisinone without telling your doctor if you are breast-feeding a baby.

How should I take nitisinone?

Take your dose of nitisinone on an empty stomach, at least one hour before a meal.

To make it easier to swallow the medicine, you may open a capsule and sprinkle the contents into a small amount of water, infant formula, or applesauce. Use this mixture right away and do not keep it for later use.

Store this medication in the refrigerator and do not allow it to freeze.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next regularly scheduled dose, skip the missed dose and take your next dose as directed.. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have taken too much of this medicine.

Symptoms of a nitisinone overdose may include skin rash, jaundice (yellowing of the skin or eyes), unusual bleeding, or problems with your eyes or vision.

What should I avoid while taking nitisinone?

Nitisinone is only part of a complete program of treatment that also includes a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You will need to avoid or restrict foods that contain tyrosine or phenylalanine.

Some of the foods that contain tyrosine include cheese, milk, sour cream, beer, wine, distilled liquor, chicken, beef, liver, fish, processed meats (bologna, hot dogs, pepperoni, hard sausages), meat tenderizer, herring or other dried fish, avocados, bananas, carrots, potatoes, oatmeal, brown rice, soy sauce, spinach, tomatoes, bean curd, raisins, red plums, garbanzo beans, soy beans, and almonds.

Foods that contain phenylalanine include diet sodas, beef, poultry, pork, fish, milk, yougurt, eggs, cheese, soybeans, soy protein, tofu, and certain nuts or seeds.

A major source of phenylalanine is the artificial sweetener aspartame (NutraSweet), which is contained in many diet or sugar-free drinks and food products. Before consuming any packaged food or beverage, carefully read the nutrition label to be sure the product does not contain phenylalanine or have a warning about phenylketonuria.

There are other foods that may contain tyrosine or phenylalanine. Be sure you are familiar with the list of foods you must avoid or restrict to help control your condition.

Nitisinone side effects

Stop using nitisinone and get emergency medical help if you have any of these serious side side effects. Some of these side effects can be caused by the medication or by your diet:
  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

  • jaundice (yellowing of the skin or eyes);

  • eye redness, pain, burning, or sensitivity to light;

  • vision changes;

  • bloody or black stools; or

  • unusual bruising or bleeding.

Other, less serious side effects may be more likely to occur. Continue using nitisinone and talk with your doctor if you have any of these side effects:

  • fever, sore throat, cough, muscle aches;

  • itching or peeling of your skin;

  • diarrhea, nausea, or constipation;

  • nervousness, trouble sleeping;

  • thirst; or

  • mild stomach pain or diarrhea.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect nitisinone?

There may be other drugs that can affect nitisinone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist has additional information about nitisinone written for health professionals that you may read.

What does my medication look like?

Nitisinone is available with a prescription under the brand name Orafidin. Other brand and generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Orafidin 2 mg--white capsule

  • Orafidin 5 mg--white capsule

  • Orafidin 10 mg--white capsule

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.02. Revision Date: 12/22/05 9:43:52 AM.



Where can I get more information about nitisinone Nitisinone ? We recommend to use www.Drugs.com

Typical mistypes for nitisinone Nitisinone
bitisinone nitisinone, mitisinone nitisinone, jitisinone nitisinone, hitisinone nitisinone, nutisinone nitisinone, njtisinone nitisinone, nktisinone nitisinone, notisinone nitisinone, n9tisinone nitisinone, n8tisinone nitisinone, nirisinone nitisinone, nifisinone nitisinone, nigisinone nitisinone, niyisinone nitisinone, ni6isinone nitisinone, ni5isinone nitisinone, nitusinone nitisinone, nitjsinone nitisinone, nitksinone nitisinone, nitosinone nitisinone, nit9sinone nitisinone, nit8sinone nitisinone, nitiainone nitisinone, nitizinone nitisinone, nitixinone nitisinone, nitidinone nitisinone, nitieinone nitisinone, nitiwinone nitisinone, nitisunone nitisinone, nitisjnone nitisinone, nitisknone nitisinone, nitisonone nitisinone, nitis9none nitisinone, nitis8none nitisinone, nitisibone nitisinone, nitisimone nitisinone, nitisijone nitisinone, nitisihone nitisinone, nitisinine nitisinone, nitisinkne nitisinone, nitisinlne nitisinone, nitisinpne nitisinone, nitisin0ne nitisinone, nitisin9ne nitisinone, nitisinobe nitisinone, nitisinome nitisinone, nitisinoje nitisinone, nitisinohe nitisinone, nitisinonw nitisinone, nitisinons nitisinone, nitisinond nitisinone, nitisinonr nitisinone, nitisinon4 nitisinone, nitisinon3 nitisinone, nitisinone bitisinone, nitisinone mitisinone, nitisinone jitisinone, nitisinone hitisinone, nitisinone nutisinone, nitisinone njtisinone, nitisinone nktisinone, nitisinone notisinone, nitisinone n9tisinone, nitisinone n8tisinone, nitisinone nirisinone, nitisinone nifisinone, nitisinone nigisinone, nitisinone niyisinone, nitisinone ni6isinone, nitisinone ni5isinone, nitisinone nitusinone, nitisinone nitjsinone, nitisinone nitksinone, nitisinone nitosinone, nitisinone nit9sinone, nitisinone nit8sinone, nitisinone nitiainone, nitisinone nitizinone, nitisinone nitixinone, nitisinone nitidinone, nitisinone nitieinone, nitisinone nitiwinone, nitisinone nitisunone, nitisinone nitisjnone, nitisinone nitisknone, nitisinone nitisonone, nitisinone nitis9none, nitisinone nitis8none, nitisinone nitisibone, nitisinone nitisimone, nitisinone nitisijone, nitisinone nitisihone, nitisinone nitisinine, nitisinone nitisinkne, nitisinone nitisinlne, nitisinone nitisinpne, nitisinone nitisin0ne, nitisinone nitisin9ne, nitisinone nitisinobe, nitisinone nitisinome, nitisinone nitisinoje, nitisinone nitisinohe, nitisinone nitisinonw, nitisinone nitisinons, nitisinone nitisinond, nitisinone nitisinonr, nitisinone nitisinon4, nitisinone nitisinon3, itisinone nitisinone, ntisinone nitisinone, niisinone nitisinone, nitsinone nitisinone, nitiinone nitisinone, nitisnone nitisinone, nitisione nitisinone, nitisinne nitisinone, nitisinoe nitisinone, nitisinon nitisinone, nitisinone nitisinone, nitisinone nitisinone, nitisinone itisinone, nitisinone ntisinone, nitisinone niisinone, nitisinone nitsinone, nitisinone nitiinone, nitisinone nitisnone, nitisinone nitisione, nitisinone nitisinne, nitisinone nitisinoe, nitisinone nitisinon, intisinone nitisinone, ntiisinone nitisinone, niitsinone nitisinone, nitsiinone nitisinone, nitiisnone nitisinone, nitisnione nitisinone, nitisionne nitisinone, nitisinnoe nitisinone, nitisinoen nitisinone, nitisinon e nitisinone, nitisinone nitisinone, nitisinone n itisinone, nitisinone intisinone, nitisinone ntiisinone, nitisinone niitsinone, nitisinone nitsiinone, nitisinone nitiisnone, nitisinone nitisnione, nitisinone nitisionne, nitisinone nitisinnoe, nitisinone nitisinoen, nnitisinone nitisinone, niitisinone nitisinone, nittisinone nitisinone, nitiisinone nitisinone, nitissinone nitisinone, nitisiinone nitisinone, nitisinnone nitisinone, nitisinoone nitisinone, nitisinonne nitisinone, nitisinonee nitisinone, nitisinone nitisinone, nitisinone nitisinone, nitisinone nnitisinone, nitisinone niitisinone, nitisinone nittisinone, nitisinone nitiisinone, nitisinone nitissinone, nitisinone nitisiinone, nitisinone nitisinnone, nitisinone nitisinoone, nitisinone nitisinonne, nitisinone nitisinonee, etc.



© Copyright by drug-information.ru 2001-2019. All rights reserved