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Generic Name: Naloxone (nal-OX-one)
Brand Name: Narcan

Naloxone is used for:

Completely or partially reversing the effects of narcotics. It may also be used to diagnose overdose of narcotics. It may also be used for other conditions as determined by your doctor.

Naloxone is a narcotic antagonist. It works by blocking opiate receptor sites, which reverses or prevents toxic effects of narcotic (opioid) analgesics.

Do NOT use Naloxone if:

  • you are allergic to any ingredient in Naloxone

Contact your doctor or health care provider right away if any of these apply to you.

Before using Naloxone :

Some medical conditions may interact with Naloxone . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart disease or a history of substance abuse

Some MEDICINES MAY INTERACT with Naloxone . However, no specific interactions are known at this time.

Ask your health care provider if Naloxone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Naloxone :

Use Naloxone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Naloxone is usually given as an injection at your doctor"s office, hospital, or clinic.
  • Do not use Naloxone if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Naloxone , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Naloxone .

Important safety information:

  • Naloxone may cause dizziness, drowsiness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Naloxone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • If you experience a return of symptoms (such as drowsiness or difficulty breathing), contact your doctor immediately.
  • Naloxone should be used with extreme caution in NEWBORNS of women who may have had dependency on narcotics; opioid withdrawal may occur.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Naloxone while you are pregnant. It is not known if Naloxone is found in breast milk. If you are or will be breast-feeding while you use Naloxone , check with your doctor. Discuss any possible risks to your baby.

If you are addicted to narcotics and are given Naloxone , you may experience WITHDRAWAL symptoms, including abnormal skin sensations; anxiety; diarrhea; fever; goose bumps; nausea; pain; rapid heartbeat; rigid muscles; runny nose; seeing, hearing, or feeling things that are not there; shivering or tremors; sneezing; sweating; trouble sleeping; and vomiting.

Possible side effects of Naloxone :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Change in mood; increased sweating; nausea; nervousness; restlessness; trembling; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dizziness; fainting; fast or irregular pulse; flushing; headache; heart rhythm changes; seizures; sudden chest pain.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately.

Proper storage of Naloxone :

Naloxone is usually handled and stored by a health care provider. If you are using Naloxone at home, store Naloxone as directed by your pharmacist or health care provider. Keep Naloxone out of the reach of children and away from pets.

General information:

  • If you have any questions about Naloxone , please talk with your doctor, pharmacist, or other health care provider.
  • Naloxone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Naloxone . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

Where can I get more information about Naloxone ? We recommend to use

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