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Generic Name: Gold Sodium Thiomalate (gold SO-dee-um thye-oh-MAH-late)
Brand Name: Myochrysine

Myochrysine has a risk of toxic reactions associated with its use ranging from severe to fatal. It is important to know the symptoms, which may include the following: blood in the urine, easy bruising or bleeding, itching, hives, rash, mouth sores, or persistent diarrhea. Be sure to discuss with your doctor what effects and symptoms to look for while taking Myochrysine . Lab tests will be required to monitor therapy.

Myochrysine is used for:

Treating rheumatoid arthritis as part of a complete program of therapy. It should not be used alone to treat arthritis. It may also be used for other conditions as determined by your doctor.

Myochrysine is an antirheumatic agent. It works by suppressing inflammation in the body.

Do NOT use Myochrysine if:

  • you are allergic to any ingredient in Myochrysine or have had a severe allergic reaction to previous exposure to gold or other heavy metals
  • you are severely debilitated or have systemic lupus erythematosus

Contact your doctor or health care provider right away if any of these apply to you.

Before using Myochrysine :

Some medical conditions may interact with Myochrysine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diabetes, congestive heart failure or other heart problems, circulation disorders, high blood pressure, Sjögren syndrome, liver or kidney problems, or recently had radiation therapy
  • if you have itching, dryness, peeling, or a skin rash (eg, eczema, hives)
  • if you have a history of blood disorders (eg, anemia) caused by medicine or you bleed easily

Some MEDICINES MAY INTERACT with Myochrysine . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Penicillamine because the risk of kidney problems and blood disorders may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Myochrysine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Myochrysine :

Use Myochrysine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Myochrysine is usually administered as an injection at your doctor"s office, hospital, or clinic. If you are using Myochrysine at home, carefully follow the injection procedures taught to you by your health care provider.
  • If Myochrysine contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of Myochrysine , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Myochrysine .

Important safety information:

  • After you receive an injection, you may experience flushing, dizziness, or sweating. These effects will usually disappear if you lie down for a few minutes.
  • Myochrysine may cause increased sensitivity to the sun and skin reactions such as itching, redness, or inflammation that may be worsened with exposure to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Myochrysine . Use a sunscreen or wear protective clothing if you must be outside for a prolonged period.
  • Myochrysine may reduce the number of clot-forming cells (platelets) in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.
  • Three to 6 months may pass before you feel the full effect of Myochrysine . Continue using injections during this time.
  • Joint pain may be worse for 1 or 2 days after your injection but it should end after the first few injections.
  • LAB TESTS, including complete blood cell counts and urine samples, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Myochrysine during pregnancy. Myochrysine is excreted in breast milk. Do not breast-feed while taking Myochrysine .

Possible side effects of Myochrysine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Stomach cramps.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; cough; dark urine; metallic taste; mouth sores; nausea; pain or numbness in the hands or feet; persistent diarrhea; purple blotches or other skin spots; seizures; shortness of breath; sore throat; thickening of the tongue; unusual bleeding or bruising; unusual weakness; vision problems; vomiting.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include blood in the urine; diarrhea; fever; hives; severe itching; vomiting.

Proper storage of Myochrysine :

Store Myochrysine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Myochrysine out of the reach of children and away from pets.

General information:

  • If you have any questions about Myochrysine , please talk with your doctor, pharmacist, or other health care provider.
  • Myochrysine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Myochrysine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.

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