Monopril

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Monopril


Generic Name: Fosinopril (foe-SIN-oh-pril)
Brand Name: Monopril

DO NOT take Monopril if you are pregnant. Monopril can cause injury and possibly death to the developing fetus when used after the third month of pregnancy. Talk with your doctor at once if you suspect that you are pregnant.


Monopril is used for:

Treating high blood pressure. It may be used alone or with other blood pressure medicines. It may also be used with other medicines for the treatment of congestive heart failure and certain other conditions as determined by your doctor that may not be listed in the professional package insert.

Monopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by decreasing a chemical that tightens blood vessels. This causes blood vessels to relax (dilate), which lowers blood pressure and decreases the workload on the heart.

Do NOT use Monopril if:

  • you are allergic to any ingredient in Monopril or any other ACE inhibitor (eg, enalapril)
  • you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Monopril :

Some medical conditions may interact with Monopril . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have or have ever had liver or kidney problems, kidney transplantation, or kidney dialysis
  • if you have bone marrow suppression, low blood counts, low blood pressure, low blood sodium, high blood potassium, narrowing or hardening of the arteries of the brain, dehydration, diabetes, systemic lupus erythematosus (SLE or lupus), scleroderma, or a collagen vascular disease (ask your doctor if you are not sure)
  • if you are scheduled to have surgery or receive anesthesia

Some MEDICINES MAY INTERACT with Monopril . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Dextran sulfate, thiazide diuretics (eg, hydrochlorothiazide) because the risk of serious damage to the kidney (eg, decreased urine output, weight gain) may be increased
  • Nonsteroidal anti-inflammatory medicines (eg, aspirin, ibuprofen, indomethacin, naproxen, celecoxib) because the effectiveness of Monopril may be decreased
  • Potassium supplements or potassium-sparing diuretics (eg, amiloride) because they may cause high blood potassium levels, resulting in listlessness, confusion, abnormal skin sensations in the arms and legs, heaviness of limbs, slowed heart rate, irregular heart rhythm, or stopping of the heart when used with Monopril
  • Lithium, sulfonylureas (eg, glyburide), or thiopurines (eg, azathioprine) because the risk of side effects may be increased by Monopril

This may not be a complete list of all interactions that may occur. Ask your health care provider if Monopril may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Monopril :

Use Monopril as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Monopril may be taken with or without food.
  • Taking Monopril at the same time each day will help you to remember to take it.
  • Do not take antacids containing aluminum, magnesium, or simethicone within 2 hours before or 2 hours after taking Monopril .
  • Drink plenty of fluids while taking Monopril . Not drinking enough fluids, as well as excessive sweating, diarrhea, or vomiting, can lead to lightheadedness or fainting.
  • If you miss a dose of Monopril , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Monopril .

Important safety information:

  • Monopril may cause dizziness or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Monopril . Using Monopril alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Monopril may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.
  • Patients being treated for high blood pressure often feel tired or run down for a few weeks after beginning therapy. Continue taking your medication even though you may not feel quite "normal." Contact your doctor or pharmacist about any new symptoms.
  • Monopril may cause a dry, unproductive cough. This symptom usually stops after treatment with Monopril is stopped.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are taking Monopril .
  • Do not use salt substitutes containing potassium without first talking with your doctor.
  • Black patients are at higher risk for certain side effects and may not respond as well to Monopril as patients of other races. If you are a black patient and your symptoms do not improve or worsen while you are taking Monopril , contact your doctor.
  • Diabetes patients - Monopril may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
  • LAB TESTS, including liver function, kidney function, blood counts, and blood pressure, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Monopril with caution in CHILDREN younger than 6 years of age. Safety and effectiveness in this age group have not been confirmed
  • PREGNANCY and BREAST-FEEDING: When Monopril is used after the third month of pregnancy, it can cause injury or even death to the developing fetus. Stop taking Monopril as soon as possible if you become pregnant. Monopril is excreted in breast milk. Do not breast-feed while taking Monopril .

Possible side effects of Monopril :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness or lightheadedness when sitting up or standing; dry cough; fatigue; fever; headache; irregular or slow heartbeat; muscle pain; nausea; persistent, nonproductive cough; shortness of breath; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; itching; dizziness; hives; difficulty swallowing or breathing; tightness in the throat; swelling of the hands, face, mouth, lips, eyes, throat, or tongue); chest pain; fainting; fever; hoarseness; unusual stomach pain; upper respiratory tract infection; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include dizziness; lightheadedness, especially upon standing; weakness.

Proper storage of Monopril :

Store Monopril at 77 degrees F (25 degrees C); excursions permitted to 59 to 86 degrees F (15 to 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Monopril out of the reach of children and away from pets.

General information:

  • If you have any questions about Monopril , please talk with your doctor, pharmacist, or other health care provider.
  • Monopril is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Monopril . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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