Methylphenidate Solution

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|Methylphenidate Solution

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Methylphenidate Solution


Generic Name: Methylphenidate Oral Solution (meth-ill-FEN-ih-date)
Brand Name: Methylin

Methylphenidate should be given with caution to patients with a history of drug dependence or alcoholism. Chronic abusive use can lead to marked tolerance and psychological dependence with varying degrees of abnormal behavior. Frank psychotic episodes can occur, especially with abuse of injections. Careful supervision is required during withdrawal from abusive use because depression may occur. Withdrawal following chronic therapeutic use may unmask symptoms of the underlying disorder that may require follow-up.


Methylphenidate Solution is used for:

Treating attention deficit hyperactivity disorder (ADHD) and uncontrollable sleep attacks (narcolepsy). It may also be prescribed for other conditions as determined by your doctor.

Methylphenidate Solution is a central nervous system stimulant. It works by blocking 2 chemicals in the brain. The exact way Methylphenidate Solution works is unknown.

Do NOT use Methylphenidate Solution if:

  • you are allergic to any ingredient in Methylphenidate Solution
  • you have severe anxiety, agitation, or tension
  • you have glaucoma
  • you have motor tics, Tourette syndrome, or a family history of Tourette syndrome
  • you are currently taken or have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) in the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Methylphenidate Solution:

Some medical conditions may interact with Methylphenidate Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of bizarre behavior, mood swings, fatigue, agitation, anxiety, tension, depression, psychosis, or abnormal thoughts or visions
  • if you have a history of seizures, convulsions, or abnormal electroencephalograms (EEGs)
  • if you have high blood pressure, have had a recent heart attack, or have other heart problems
  • if you have high thyroid hormone levels or a history of substance abuse or alcoholism

Some MEDICINES MAY INTERACT with Methylphenidate Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Guanethidine because the effectiveness may be decreased by Methylphenidate Solution
  • MAO inhibitors (eg, phenelzine ) because the actions and side effects of Methylphenidate Solution may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Methylphenidate Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Methylphenidate Solution:

Use Methylphenidate Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Methylphenidate Solution comes with an additional patient leaflet. Read it carefully.
  • Methylphenidate Solution is usually taken once each day in the morning before breakfast, preferably 30 to 45 minutes before eating. If stomach upset occurs, it may be taken with food.
  • If medicine causes difficulty sleeping, take last dose before 6 pm.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure this dose.
  • If you miss a dose of Methylphenidate Solution and you take one dose daily, take the missed dose if you remember the same day. Skip the missed dose if you do not remember until the next day. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Methylphenidate Solution.

Important safety information:

  • Methylphenidate Solution may cause dizziness, blurred vision, or lightheadedness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Methylphenidate Solution. Using Methylphenidate Solution alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • Methylphenidate Solution should not be used to treat depression or prevent or treat normal tiredness.
  • Do not drink alcohol while taking Methylphenidate Solution.
  • There have been very rare reports of neuroleptic malignant syndrome (NMS). It is uncertain whether these cases were caused by Methylphenidate Solution alone or by some other combination factors. Notify your doctor if you experience fever, excessive sweating, shortness of breath, inability to control bladder, muscle rigidity, tremors, or unusual muscle movements.
  • LAB TESTS, such as complete blood cell counts and platelet counts, may be needed to monitor for side effects. Keep all doctor and laboratory appointments.
  • Methylphenidate Solution may reduce weight gain or growth in CHILDREN. Your health care provider will watch weight and height carefully. Your doctor may stop treatment if growing or gaining weight are not as your doctor expects. Contact your health care provider if you do not see improvement in symptoms within 1 month. Methylphenidate Solution is not recommended for use in CHILDREN younger than 6 years of age; safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you are pregnant or plan on becoming pregnant, discuss with your doctor the benefits and risks of using Methylphenidate Solution during pregnancy. It is unknown if Methylphenidate Solution is excreted in breast milk. If you are or will be breast-feeding while using Methylphenidate Solution, contact your doctor or pharmacist to discuss the risks to your baby.

When used for long periods of time or at high doses, Methylphenidate Solution may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Methylphenidate Solution stops working well. Do not take more than prescribed.

Abuse of Methylphenidate Solution can lead to DEPENDENCE. Tell your health care provider if you have ever abused or had dependence on alcohol or drugs, or if you are now abusing or dependent on alcohol or substances.

Possible side effects of Methylphenidate Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Decreased appetite (more severe in children); diarrhea; dizziness; drowsiness; dry mouth; fever; hair loss; headache; itching; joint pain; loss of appetite; nervousness; sleeplessness; stomach upset; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bruising; changes in heart rate (fast or slow); changes in mood or personality; chest pain or pounding in the chest; confusion; convulsions or seizures; depression; involuntary muscle movements; joint pain; psychosis (abnormal thinking or hallucinations, hearing abnormal sounds); seizures; sore throat and fever; vision changes or blurred vision; weight loss; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include dilated pupils; fast heartbeat; flushing; hallucinations; loss of consciousness; muscle twitching; nervousness; seizures; severe or persistent headache; sweating; tremors; twitching; vomiting.

Proper storage of Methylphenidate Solution:

Store Methylphenidate Solution between 68 and 77 degrees F (20 and 25 degrees C) in the original container away from heat, moisture, and light. Do not store in the bathroom. Keep Methylphenidate Solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Methylphenidate Solution, please talk with your doctor, pharmacist, or other health care provider.
  • Methylphenidate Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Methylphenidate Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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