Methylergonovine

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|Methylergonovine

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Methylergonovine


Generic Name: Methylergonovine Tablets (meth-ill-er-goe-NOE-veen)
Brand Name: Methergine

Methylergonovine is used for:

Preventing and treating bleeding after delivery of a baby. It may also be used for other conditions as determined by your doctor.

Methylergonovine is a uterine stimulant. It works by increasing uterine contractions, which helps reduce blood loss after the baby is delivered.

Do NOT use Methylergonovine if:

  • you are allergic to any ingredient in Methylergonovine
  • you are pregnant
  • you have high blood pressure or blood poisoning
  • you are taking an azole antifungal (eg, itraconazole, ketoconazole, voriconazole), certain protease inhibitors (eg, delavirdine, indinavir, nelfinavir, ritonavir), efavirenz, a ketolide antibiotic (eg, telithromycin), a macrolide antibiotic (eg, clarithromycin, erythromycin), or sumatriptan

Contact your doctor or health care provider right away if any of these apply to you.

Before using Methylergonovine :

Some medical conditions may interact with Methylergonovine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a blood infection or a history of blood vessel problems, stroke, liver problems, kidney problems, or heart disease
  • if you have eclampsia or preeclampsia

Some MEDICINES MAY INTERACT with Methylergonovine . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Clotrimazole, ergot alkaloids (eg, ergotamine), fluconazole, fluoxetine, fluvoxamine, grapefruit juice, nefazodone, saquinavir, or zileuton because they may increase the risk of Methylergonovine "s side effects
  • Azole antifungals (eg, itraconazole, ketoconazole, voriconazole), certain protease inhibitors (eg, delavirdine, indinavir, nelfinavir, ritonavir), efavirenz, ketolide antibiotics (eg, telithromycin ), macrolide antibiotics (eg, erythromycin, clarithromycin), or sumatriptan because the risk of severe blood vessel constriction and decreased oxygen to the brain and other tissues may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Methylergonovine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Methylergonovine :

Use Methylergonovine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Methylergonovine by mouth with or without food.
  • Grapefruit and grapefruit juice may increase the risk of side effects from Methylergonovine . Talk to your doctor before including grapefruit or grapefruit juice in your diet while taking Methylergonovine .
  • Do not use Methylergonovine for more than 1 week unless instructed by your doctor.
  • If you miss a dose of Methylergonovine , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Methylergonovine .

Important safety information:

  • Methylergonovine may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Methylergonovine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Use Methylergonovine with caution in the ELDERLY; they may be more sensitive to its effects.
  • Use Methylergonovine with extreme caution in CHILDREN; safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Do not use Methylergonovine if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. Methylergonovine is found in breast milk. If you are or will be breast-feeding while you use Methylergonovine , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Methylergonovine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness or lightheadedness; cramping of the uterus; headache; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; chest pain or tightness; hallucinations; irregular heartbeat; leg cramps; ringing in the ears; seizure; severe headache; shortness of breath.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include abdominal pain; coma; difficulty breathing; nausea; numbness; seizures; severe headache or dizziness; tingling of the extremities; vomiting.

Proper storage of Methylergonovine :

Store Methylergonovine below 77 degrees F (20 degrees C) in a tight, light-resistant container. Keep Methylergonovine out of the reach of children and away from pets.

General information:

  • If you have any questions about Methylergonovine , please talk with your doctor, pharmacist, or other health care provider.
  • Methylergonovine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Methylergonovine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition 06.4.1.002
Copyright © 2006 Wolters Kluwer Health, Inc.




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