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|Methscopolamine/Pseudoephedrine Extended-Release Tablets

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Methscopolamine/Pseudoephedrine Extended-Release Tablets

Generic Name: Methscopolamine/Pseudoephedrine Extended-Release Tablets (meth-skoe-POL-a-meen/soo-doe-e-FED-rin)
Brand Name: Examples include Amdry-D and Extendryl PSE

Methscopolamine/Pseudoephedrine Extended-Release Tablets is used for:

Relieving congestion due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Methscopolamine/Pseudoephedrine Extended-Release Tablets is a decongestant and anticholinergic combination. It works by relieving nasal congestion by shrinking the nasal mucous membranes, which promotes nasal drainage, and decreasing lung secretions, which dries the chest.

Do NOT use Methscopolamine/Pseudoephedrine Extended-Release Tablets if:

you are allergic to any ingredient in Methscopolamine/Pseudoephedrine Extended-Release Tablets or to similar medicines (eg, ephedrine)
you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
you have severe heart blood vessel disease; severe high blood pressure; severe heart problems; a rapid heartbeat; narrow-angle glaucoma; severe or uncontrolled bleeding; severe irritation of the esophagus or other serious problems with the esophagus (eg, esophageal achalasia); peptic ulcer; a blockage of your stomach, bowel, or bladder; bowel motility problems; severe bowel inflammation (eg, ulcerative colitis); or certain muscle problems (eg, myasthenia gravis)
you are unable to urinate or you are having an asthma attack

Contact your doctor or health care provider right away if any of these apply to you.

Before using Methscopolamine/Pseudoephedrine Extended-Release Tablets:

Some medical conditions may interact with Methscopolamine/Pseudoephedrine Extended-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of diabetes, an enlarged prostate or other prostate problems, bladder or kidney problems, severe bowel problems, high blood pressure, asthma, nerve problems, heart problems, blood vessel problems, blood clots, trouble urinating, a hiatal hernia, an adrenal gland tumor, glaucoma or increased eye pressure, breathing problems during sleep, stroke, seizures, or an overactive thyroid
if you have diarrhea

Some MEDICINES MAY INTERACT with Methscopolamine/Pseudoephedrine Extended-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine ), or methyldopa because the risk of severe high blood pressure, fever, fast heartbeat, and seizures may be increased
Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
Anticholinergic medicines (eg, benztropine, hyoscyamine, trihexyphenidyl), certain medicines for mental or mood disorders (eg, thioridazine), tricyclic antidepressants (eg, amitriptyline), or urinary alkalinizers (eg, sodium bicarbonate) because they may increase the risk of Methscopolamine/Pseudoephedrine Extended-Release Tablets"s side effects
Bromocriptine because the risk of its side effects may be increased by Methscopolamine/Pseudoephedrine Extended-Release Tablets
Guanadrel, guanethidine, mecamylamine, or reserpine because their effectiveness may be decreased by Methscopolamine/Pseudoephedrine Extended-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Methscopolamine/Pseudoephedrine Extended-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Methscopolamine/Pseudoephedrine Extended-Release Tablets:

Use Methscopolamine/Pseudoephedrine Extended-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Methscopolamine/Pseudoephedrine Extended-Release Tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
Swallow Methscopolamine/Pseudoephedrine Extended-Release Tablets whole. Do not break, crush, or chew before swallowing. Some brands of Methscopolamine/Pseudoephedrine Extended-Release Tablets may be broken in half before taking. If you have difficulty swallowing the whole tablet, ask your pharmacist if your brand of medicine may be broken in half.
If you miss a dose of Methscopolamine/Pseudoephedrine Extended-Release Tablets and you are taking it regularly, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Methscopolamine/Pseudoephedrine Extended-Release Tablets.

Important safety information:

Methscopolamine/Pseudoephedrine Extended-Release Tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Methscopolamine/Pseudoephedrine Extended-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
If your symptoms do not get better within 7 days or if they get worse, or if you develop a high fever or persistent headache, check with your doctor.
Methscopolamine/Pseudoephedrine Extended-Release Tablets may cause dry mouth. To relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.
Avoid large amounts of food or drink that have caffeine (eg, coffee, tea, cocoa, cola, chocolate).
Methscopolamine/Pseudoephedrine Extended-Release Tablets may make your eyes more sensitive to sunlight. It may help to wear sunglasses.
Methscopolamine/Pseudoephedrine Extended-Release Tablets may reduce sweating. Do not become overheated in hot weather or during exercise or other activities; heatstroke may occur.
Do not take diet or appetite control medicines while you are taking Methscopolamine/Pseudoephedrine Extended-Release Tablets without checking with your doctor first.
Methscopolamine/Pseudoephedrine Extended-Release Tablets has pseudoephedrine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
If you have trouble sleeping, ask your doctor or pharmacist about the best time of the day to take Methscopolamine/Pseudoephedrine Extended-Release Tablets.
Tell your doctor or dentist that you take Methscopolamine/Pseudoephedrine Extended-Release Tablets before you receive any medical or dental care, emergency care, or surgery.
Diabetes patients - Methscopolamine/Pseudoephedrine Extended-Release Tablets may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Methscopolamine/Pseudoephedrine Extended-Release Tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Methscopolamine/Pseudoephedrine Extended-Release Tablets.
Use Methscopolamine/Pseudoephedrine Extended-Release Tablets with caution in the ELDERLY; they may be more sensitive to its effects.
Methscopolamine/Pseudoephedrine Extended-Release Tablets should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: It is not known if Methscopolamine/Pseudoephedrine Extended-Release Tablets can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Methscopolamine/Pseudoephedrine Extended-Release Tablets while you are pregnant. Methscopolamine/Pseudoephedrine Extended-Release Tablets is found in breast milk. Do not breast-feed while taking Methscopolamine/Pseudoephedrine Extended-Release Tablets.

Possible side effects of Methscopolamine/Pseudoephedrine Extended-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; restlessness; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; mental or mood changes; seizures; severe dizziness, lightheadedness, or headache; tremor; vision changes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include deep sleep or loss of consciousness; hot or cool skin; irregular heartbeat; irritability, anxiety, or panic; large pupils; numbness or tingling in the arms or legs; seizures; slowed or shallow breathing.

Proper storage of Methscopolamine/Pseudoephedrine Extended-Release Tablets:

Store Methscopolamine/Pseudoephedrine Extended-Release Tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Methscopolamine/Pseudoephedrine Extended-Release Tablets out of the reach of children and away from pets.

General information:

If you have any questions about Methscopolamine/Pseudoephedrine Extended-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
Methscopolamine/Pseudoephedrine Extended-Release Tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about this medicine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006

Database Edition 06.4.1.002

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