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M-M-R II, |M-M-R II

M-M-R II

Generic Name: measles, mumps, and rubella (MMR) vaccines (MEE zulls, MUMPS, and rue BEH la)
Brand Names: M-M-R II

What are measles, mumps, and rubella vaccines?

Measles, mumps, and rubella are serious diseases caused by viruses. They are spread from person to person through the air. Vaccines for these diseases expose the individual to a small amount of the virus (or to a protein from the virus) and cause the body to develop immunity to the disease.

Measles virus causes a rash, cough, runny nose, eye irritation, and fever. It can lead to ear infection, pneumonia, seizures (jerking and staring), brain damage, and death.

Mumps virus causes fever, headche, and swollen glands. It can lead to deafness, meningitis (infection of the brain and spinal cord covering), painful swelling of the testicles or ovaries, and rarely, death.

Rubella (German Measles) virus causes rash, mild fever, and arthritis (mostly in women). If a woman gets rubella while she is pregnant , she could have a miscarriage or her baby could be born with serious birth defects.

Measles, mumps, and rubella vaccine (MMR) can help prevent these diseases. Most people who are vaccinated with MMR will not get these diseases. Many more people would get these diseases if vaccination did not occur.

What is the most important information I should know about measles, mumps, and rubella vaccines?

If you have a minor illnesses, such as a cold, you can still receive MMR vaccine. If you are moderately or severely ill, it is generally recommended that you wait until you have recovered before getting MMR vaccine.

What should I discuss with my healthcare provider before receiving measles, mumps, and rubella vaccines?

• gelatin,

• the antibiotic neomycin, or

• a previous dose of MMR.

Before receiving MMR vaccine, talk to your doctor if you

• have HIV or AIDS or another disease that affects the immune system;

• are taking a medication that affects the immune system (e.g. steroids, anti-rejection medications);

• have cancer;

• are receiving cancer treatment with x-rays, radiation, or medication;

• have ever had a low platelet count (a blood disorder); or

• have recently had a blood transfusion or been given other blood products.

You may not be able to receive MMR vaccine at this time or you may require special monitoring.

If you have a minor illnesses, such as a cold, you can still receive MMR vaccine. If you are moderately or severely ill, it is generally recommended that you wait until you have recovered before getting MMR vaccine.

How are measles, mumps, and rubella vaccines administered?

Your doctor, nurse, or other healthcare provider will administer measles, mumps, and rubella vaccine as an injection.

Children should get 2 doses of MMR vaccine, the first at 12-15 months of age and the second at 4 -6 years of age. These are the recommended ages. Children can get the second dose at any age, as long as it is at least 28 days after the first dose.

Some adults should also get MMR vaccine. Generally, anyone 18 years of age or older, who was born after 1956, should get at least one dose of MMR vaccine, unless they can show that they have had either the vaccines or the diseases.

MMR may be given at the same time as other vaccines.

Your doctor may recommend reducing fever and pain by taking an aspirin-free pain reliever such as acetaminophen (Tylenol, Tempra, others) or ibuprofen (Motrin, Advil, others) when the shot is given and for the next 24-48 hours. Your healthcare provider can tell you the appropriate dosages of these medications.

What happens if I miss a dose?

Contact your doctor if a dose of MMR vaccine is missed.

What happens if I overdose?

An overdose of MMR vaccine is unlikely to occur.

What should I avoid before or after getting measles, mumps, and rubella vaccines?

There are no restrictions on food, beverages, or activity before or after receiving the MMR vaccine.

Measles, mumps, and rubella vaccines side effects

Getting measles, mumps, or rubella disease is much riskier than getting MMR vaccine. However, a vaccine, like any medicine, is capable of causing serious problems, such as severe allergic reactions. The risk of MMR vaccine causing serious harm, or death, is extremely small.

• a serious allergic reaction including swelling of the lips, tongue, or face; difficulty breathing; closing of the throat; hives; paleness; weakness; dizziness; or a fast heart beat; (less than 1 out of 1 million doses);

• deafness (very rare);

• long-term seizures, coma, or lowered consciousness (very rare);

• permanent brain damage (very rare);

• seizures (jerking or staring) caused by fever (about 1 out of 3,000 doses); or

• temporary low platelet count, which can cause a bleeding disorder (about 1 out of 30,000 doses).

Signs of a serious allergic reaction would occur within a few minutes to a few hours after the shot. High fever or seizures related to MMR vaccine would occur 1 to 2 weeks after the shot.

Other less serious side effects may be more likely to occur. Talk to your doctor if your child experiences:

• fever (up to 1 person out of 6);

• mild rash (about 1 person out of 20);

• swelling of glands in teh cheeks or neck (rare);

• temporary stiffness and pain in the joints, mostly in teenage or adult women (up to 1 out of 4).

If fever, rash, or swollen glands occur, it is usually within 7-12 days after the shot. They occur less often after the second dose of MMR vaccine.

Your doctor may recommend reducing fever and pain by taking an aspirin-free pain reliever such as acetaminophen (Tylenol, Tempra, others) or ibuprofen (Motrin, Advil, others) when the shot is given and for the next 24-48 hours. Your healthcare provider can tell you the appropriate dosages of these medications.

Side effects other than those listed here may also occur. Contact your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect measles, mumps, and rubella vaccines?

• an oral or injectable steroid medication such as betamethasone (Celestone), cortisone (Cortone), dexamethasone (Decadron, Dexone), hydrocortisone (Cortef, Hydrocortone), methylprednisolone (Medrol), prednisolone (Prelone, Pediapred), prednisone (Orasone, Deltasone, others), or triamcinolone (Aristocort);

• an inhaled or nasal steroid such as beclomethasone (Qvar, Beclovent, Beconase, Vanceril, Vancenase), budesonide (Pulmicort, Rhinocort), flunisolide (Aerobid, Nasalide, Nasarel), fluticasone (Flovent, Flonase), mometasone (Nasonex), or triamcinolone (Azmacort, Nasacort);

• treatment for cancer with chemotherapy (medication), radiation, or x-rays;

• azathioprine (Imuran);

• basiliximab (Simulect);

• cyclosporine (Sandimmune, Neoral, Gengraf);

• etanercept (Enbrel);

• leflunomide (Arava);

• muromonab-CD3 (Orthoclone);

• mycophenolate mofetil (CellCept);

• sirolimus (Rapamune); or

• tacrolimus (Prograf).

Measles, mumps, and rubella vaccines can be given at the same time as other vaccinations.

Where can I get more information?

• Your doctor or pharmacist may have additional information or suggest additional resources regarding MMR vaccines.

• Remember, keep this and all other medicines out of the reach of children, never share medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.