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Kayexalate, Kionex, |Kayexalate Kayexalate

Kayexalate

Generic Name: sodium polystyrene sulfonate (SEW dee um paw lee STEER een SULL foe nate)
Brand Names: Kayexalate, Kionex

What is sodium polystyrene sulfonate?

Sodium polystyrene sulfonate is an ion-exchange resin. It loses a sodium ion, that is replaced by a potassium ion. This reduces potassium in the blood.

Sodium polystyrene sulfonate is used to treat hyperkalemia (high levels of potassium in the blood).

Sodium polystyrene sulfonate may also be used for purposes other than those listed here.

What is the most important information I should know about sodium polystyrene sulfonate?

What should I discuss with my health care provider before taking sodium polystyrene sulfonate?

Before taking sodium polystyrene sulfonate, talk to your doctor if you have

• congestive heart failure;

• high blood pressure;

• swelling;

• a low level of calcium or potassium in the blood; or

• are on a salt restricted diet or are taking a potassium supplement or a potassium-sparing diuretic such as K-Dur, Klor-Con, and others;

You may not be able to take sodium polystyrene sulfonate or you may require a dosage adjustment or special monitoring during treatment.

How should I take sodium polystyrene sulfonate?

Take polystyrene sulfonate exactly as directed by your doctor. If you do not understand these instructions, ask your doctor, nurse, or pharmacist to explain them to you.

Sodium polystyrene sulfonate is usually administered by a healthcare professional.

Take the oral suspension by mouth as directed by your doctor. Shake the suspension well before measuring a dose. To ensure you get the correct dose, use a dose measuring spoon or cup to measure a dose, not a regular table spoon.

Sodium polystyrene sulfonate can also be given as an enema (into the rectum). Follow your doctor"s instructions.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next regularly scheduled dose as directed. Do not take a double dose of this medication.

What happens if I overdose?

Symptoms of a sodium polystyrene sulfonate overdose are not known.

What should I avoid while taking sodium polystyrene sulfonate?

Sodium polystyrene sulfonate side effects

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

• chest pain;

• irregular heartbeats or changes in heartbeat;

• irritability or depression;

• increased thirst or urination;

• muscle spasms;

• rectal or lower abdominal pain; or

• unusual swelling or weakness.

Other, less serious side effects may be more likely to occur. Talk to your doctor if you experience

• diarrhea or constipation;

• nausea or vomiting; or

• decreased appetite.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect sodium polystyrene sulfonate?

Before taking an ACE inhibitor, tell your doctor if you are taking any of the following drugs:

• a heart medicine, especially digoxin (Lanoxin);

• a potassium-sparing diuretic (water pill) such as triamterene (Dyrenium, Maxzide, Dyazide), spironolactone (Aldactone), or amiloride (Midamor);

• a potassium supplement such as K-Dur, Klor-Con, and others;

• a salt substitute that contains potassium; or

• a calcium supplement.

You may not be able to take sodium polystyrene sulfonate, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Antacids that contain calcium, aluminum, or magnesium such as Tums, Rolaids, Maalox and others may decrease the effects of sodium polystyrene sulfonate. Do not take an antacid without first talking to your doctor during treatment with sodium polystyrene sulfonate.

Drugs other than those listed here may also interact with sodium polystyrene sulfonate or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

• Your pharmacist has additional information about sodium polystyrene sulfonate written for health professionals that you may read.

What does my medication look like?

Sodium polystyrene sulfonate is available with a prescription under the brand names Kayexalate and Kionex. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.